Clinicwide Orientation to Treating Patients with OUD

The Pre-Implementation Planning Team should hold initial training to orient all practice or clinic staff, including nonclinical staff, to the nature of OUD and to MOUD as a form of treatment. The goal of this training is to help improve staff's basic understanding of the patients they will serve and the treatment and recovery process. The following items should be key components of this training:

• Explain how addiction affects brain chemistry: Understanding that OUD leads to fundamental changes in the brain can help reinforce that it is a chronic disease, like diabetes. Build an understanding of risk and protective factors and of the kinds of behaviors and challenges common among people living with OUD. Increase the understanding of withdrawal symptoms, compassion for the real discomfort of opioid withdrawal, and how avoiding withdrawal is a key driver to reducing opioid use.

Descriptions from people who were using illicitly-made fentanyl when they started buprenorphine treatment:²

• Teach how to spot the signs and symptoms of OUD: All staff should have a basic understanding of behaviors, side effects, and complications of OUD that patients may present with. They should know and understand the reasons for practice policies and expectations for patient behavior while in treatment.
• Describe the medications for OUD and how they work: Educate staff about MOUD as the first step to a low-threshold, person-centered treatment approach; that MOUD is the standard of care so primary care should plan to provide it. Describe each of the three FDA approved medications—methadone, buprenorphine, and naltrexone—and how and where they are used. Explain why buprenorphine is the preferred medication option in primary care settings. Highlight the value of providing medication as soon as possible after a patient is identified as having an OUD. Explain that it is essential to continue providing care to patients even when they continue to use substances. Emphasize that although a "whole-person" approach with psychosocial supports is ideal, MOUD is associated with greater treatment retention and decreased mortality among people with OUD even if no other services are available.^3,4
• Explain how buprenorphine is used to treat OUD: Describe the effect of buprenorphine on the mu opioid receptors in the brain, known as their mechanisms of action. Describe the various forms of buprenorphine, including the longer-acting injectable forms, and how the oral forms are often combined with naloxone. Note that higher dosages of buprenorphine may be required for those who have been using high potency synthetic opioids like fentanyl. Use visual aids and handouts to reinforce these concepts.
• Explain how naloxone can reverse overdose: Stress that naloxone should be provided along with any prescription for opioids and with buprenorphine for patients with OUD. If possible, also provide naloxone to family and close friends. It is preferable to physically give them the medication since prescriptions often go unfilled. For more information see Mitigating Overdose Risk.
• Highlight the effectiveness of MOUD: Teach staff about the positive impact MOUD can have on patient's lives. Show them the research demonstrating that MOUD can decrease mortality, reduce opioid use, and increase retention in treatment. Acknowledge that no one approach works for everyone and that it is critical to adapt the approach to the individual patient's needs and preferences. Also, emphasize that, while recovery is an achievable goal, it will take time. As with any chronic disease, recurrence of use is common and is not a sign of failure but rather the need to adjust the patient's treatment plan.

• Highlight the local context: Gather local county and state data to help contextualize the opioid epidemic in your community. Use these data in training with all staff to start a discussion about the importance of offering medications for OUD.
• Prepare staff to speak to patients and families about medications to treat OUD: Front desk staff and other providers may receive questions or field concerns from other patients or members of the community about MOUD. Provide tips and talking points for staff so they know how to discuss the medications and describe your practice's approach to treatment. This approach can help create a common understanding about what you are and are not doing as a practice, while dispelling some myths about medications for OUD and individuals with SUDs. (Of note, talking about myths can reinforce the myths instead of combatting them.)^6-8

Hear a family physician who treats OUD in his small primary care practice: Prescribe with Confidence | FDA.

Stigma against people with OUD and against treating OUD with medications is a treatment barrier both within the community and the healthcare system.^9,10 This stigma can discourage individuals from seeking treatment for fear it may jeopardize their employment or harm their social relationships.¹¹ The criminalization of drug use further reinforces negative perceptions of people with OUD.¹² Finally, individuals who belong to marginalized groups (e.g., based on race/ethnicity, socioeconomic status, or mental health conditions), may experience the stigma even more strongly.¹³

Stigma is common among healthcare providers as well, to the detriment of patients with SUD. The medical viewpoint of substance use disorders as a chronic disease has been a part of clinical guidelines for more than a decade,¹⁴ yet some providers hold onto negative and judgmental stereotypes. Consider the following:

• Misconceptions about the use and effectiveness of medications for OUD can make some providers reluctant to prescribe it.¹⁵
• One survey of primary care physicians found that one-third did not perceive OUD medication treatment to be more effective than non-medication (i.e., drug-free) treatment or safe for long-term use.¹⁶
• Provider stigma can negatively affect patient care and outcomes. For example, primary care providers who hold greater stigmatizing attitudes were less likely to prescribe medications for OUD or support policies to increase access to these medications.¹⁷

To mitigate these barriers, it is crucial to educate all staff about the science of addiction, OUD, and medications for OUD, even those who will not be working directly with patients who are receiving the medications. Stigma is often driven by fear or misunderstanding. Education should focus on facts and compassion and should not be used to embarrass staff.

Trainings to reduce stigma among healthcare providers can contribute to improving the quality of care for patients with SUDs. These trainings often include educational components that address the root causes of stigma, such as misconceptions about addiction and biases against people who use substances.¹⁸ The following strategies may help convince staff:

• Testimonials and Interaction: Interactive elements, such as role-playing and direct interactions with individuals who have lived experience with substance use, are also effective in reducing stigma.¹⁹ Sharing personal experiences and real-world success stories can be a powerful tool to humanize individuals with OUD and show that recovery is possible. Exposure to and stories about people in recovery can help overcome these inaccurate negative beliefs. Invite individuals in recovery who have received medications for OUD or their families to speak with practice staff. Your staff may also be willing to speak about their own personal or professional experience with OUD. If you are interested in hearing more success stories and examples, visit PCSS to learn how primary care providers are making a difference with MOUD treatment. For example, one nurse said,

  "Buprenorphine treatment for individuals, who want recovery, means freedom from the enslaving clutches of addiction. Ask anyone who has been there. Addiction is a full time [sic] job. My patients describe it as a vicious cycle of getting money to get drugs, to avoid the agony of withdrawal. Anyone who wants to get their life back should be able to find hope from those of us who have dedicated our professional lives to saving the lives of others."⁵

  Two patients have said,²⁰

  "Not only has [buprenorphine] given me another chance at life, it has given my kids their daddy back!"

  "After 2 days of being on Suboxone® I laughed. I could not believe that I had laughed and meant it. I felt it, I was living again. I began feeling all sorts of feelings. I felt like I was myself again."

• Facts and Figures: It may be necessary to explain to staff the importance of treating people with MOUD. For some staff, presenting information will help convince them of the need. Presenting state- and county-level statistics about the opioid epidemic can help contextualize and localize the issue. Highlighting the treatment gap and the lack of providers of medications for OUD may help encourage some to treat people with medications for OUD. Others who are skeptical of medications for OUD may need to understand that medications for OUD is an evidence-based practice that has been shown to improve patient outcomes.²¹

Multi-component interventions that combine education, training, and structural changes within healthcare settings have shown to be particularly effective.²² Other interventions that combined education, training, and in-person contact with people in recovery have been shown to enhance provider-client interaction.²³ These trainings not only improve provider attitudes but also enhance patient outcomes by fostering a more supportive and non-judgmental healthcare environment.^24-27

Your ability to engage patients in treatment and keep them involved in care depends on providing a welcoming environment. Positive staff interactions with patients can help create a supportive practice environment and promote engagement and retention in treatment, reducing the risk of continued substance use, overdose, and death.²⁸ Engaging patients in prevention, diagnosis, and treatment (including medications) for OUD are the first steps. All aspects of whole-person care, including psychosocial support and additional services, can be realized once those are in place.

Train all staff, including front office staff, on how to interact with patients in a respectful and positive manner, as many patients are sensitive to being stigmatized for using drugs. During these trainings, ask staff how they would respond to hypothetical scenarios or use role play to demonstrate appropriate responses. Allow staff to ask any questions they may have and to share their concerns.^29,30

As described in the previous section, Confront Stigma as a Barrier to Care, patients can quickly perceive judgmental attitudes or behaviors from staff, even if they are unintentional. Individuals with OUD often experience intense guilt or shame, so staff should be careful not to reinforce these feelings.

Incorporating motivational interviewing^31,32 techniques can help providers develop more empathetic communication skills.¹⁹ Free or low-cost training in motivational interviewing and basic behavior change techniques can help you conduct more successful medication management visits. Motivational interviewing helps providers and staff understand what really matters to the patients, why they are in treatment, and how they define success.

In practices with a more comprehensive array of services for people with OUD, staff should be trained on how to assess patient needs and enhance patient motivation. Customer service techniques can embed motivational interviewing principles, such as:³³

• Treating patients with OUD with the same respect as you treat other patients;
• Asking open-ended questions to discuss the situation with the patient;
• Focusing on the patient's reasons for seeking treatment;
• Expressing empathy and compassion;
• Using reflective listening to summarize what you have just heard;
• Asking patients their preferences for in-person vs. telehealth visits and any anticipated issues with maintaining scheduled appointments; and
• Giving patients an opportunity to ask questions.

Training to Support Medication Management Visits: Motivational interviewing techniques can be used during initial clinical assessments and ongoing medication management visits to develop a treatment plan that meets patients' needs. To encourage retention in treatment, ask patients what might lead them to discontinue treatment and what you can do to help ensure they attend their scheduled visits. To learn more, see Resources.

You can prescribe buprenorphine and treat patients with OUD even if mental health services are not available.

The primary focus of low-threshold treatment is stabilizing patients with medication first, with the goal of keeping them alive. Some patients may engage in supportive services as they progress in their recovery.³⁴ In addition, not all patients require intensive counseling or psychosocial supports to meet treatment goals and work toward recovery.

Over 60% of people with OUD have had some form of mental illness in the past year, including 27% who have a serious mental illness.³⁵ Depending on whether and how your practice has integrated mental health services, you may need to rely on external collaborators to address mental health needs. Familiarize staff with your referral partners, keeping in mind that some of these services may be provided through telehealth or smart phone-based apps as well as in the local community as described in Counseling and Other Psychosocial Supports. Just giving the patient a list of resources is unlikely to result in solutions to the problems they face. It is best if you can develop an ongoing collaboration with these service organizations, with closed loop referrals and ongoing communication about patient progress, with appropriate patient consent. Discuss the types of supports that are available such as:

• Drug and alcohol counseling;
• Mental health counseling and therapy;
• Support groups such as Alcoholics Anonymous, Narcotics Anonymous, and Self-Management and Recovery Training [SMART] Recovery. (Know that some of these recovery groups may have a strong bias toward medication-free recovery and will not be appropriate for patients receiving MOUD, as they will not support this treatment approach);
• Peer providers such as certified peer specialists, peer support specialists, and recovery coaches. (As with support groups, peer providers should be vetted first for whether they support MOUD); and
• Help with health-related social needs, such as safe housing, employment, transportation, and childcare. (These may need to be addressed to maximize their chance of recovery.³⁶ FindHelp.org is a national resource that lists organizations that can assist with food, housing, transportation, childcare, etc).

To successfully support their patients with OUD and respond to patient needs, care teams need to be attuned to the lifestyle and social factors that may affect treatment outcomes. They should be familiar with the available services and supports and trained on how to assess patients' needs and be prepared to respond to them.

Addressing challenging behaviors: As with any patient, staff may encounter patients with OUD that present challenging behaviors, so staff should be prepared to respond. Try to discuss this topic without reinforcing stigma. Dr. Nora Volkow, Director of the National Institute on Drug Abuse (NIDA), talks about the way opioids "hijack the brain" and can lead to harmful and socially unacceptable behaviors.³⁷ Recognizing this phenomenon, develop and train staff on approaches that reward positive behaviors and discourage problematic behaviors. (See Challenging Patient Behaviors and Concerns). Train staff on these policies and use role play scenarios to help them practice their responses.

Train staff on procedures to detect and Reduce Risks of Diversion. Diversion is when patients give or sell their medication (buprenorphine, in this case) to another individual. This is an issue that has been controversial and that has been studied extensively. Some researchers have found that sharing buprenorphine may even have positive public health effects by reducing overdoses for people with OUD who are not yet in treatment. The availability of LAI buprenorphine can also essentially eliminate the risk of diversion.³⁸

After determining your practice's approach to treating OUD, train staff on new or revised procedures and workflows before they are implemented. Emphasize how these changes affect staff roles and responsibilities. Diagrams or flowcharts can help staff visualize these changes.

Give staff time to digest and understand these changes on their own and then provide an opportunity for staff to share their questions or concerns in a group setting. Demonstrate the new activity, and have staff practice it themselves. Staff who feel comfortable after being trained on the new workflows can help teach or support others in the practice. The section General Operations provides information on what will need to be developed.