Once you have integrated buprenorphine into your practice, consider whether you can facilitate your patients' engagement with psychosocial supports. Your role can be as basic as providing patients with a referral list, although a process that involves collaboration with the other service providers is more likely to result in connections that improve outcomes. For more whole-person care, you could ensure your patient connects with the appropriate support, and coordinate care with that professional (as appropriate).
Not all patients who receive medications for OUD will need or be willing to engage with psychosocial supports. The SAMHSA Treatment Improvement Protocol (TIP) 63 expert panel notes that “counseling and other services should target patients' needs, not be arbitrarily required as a condition for receiving OUD medication.” However, over 60% of people with OUD have had a mental illness in the past year, with 27%58 having a serious mental illness.2 Common mental health disorders co-morbid with OUD include depression, anxiety, post-traumatic stress disorder, and attention-deficit/hyperactivity disorder (ADHD).3 In addition, people with OUD are also more likely to die by Suicide: OUD and injection drug use are associated with a 13-fold increased risk of suicide relative to the general population.4
Practices ensure that patients who are willing and in need engage in some form of mental health services or other psychosocial supports. Ongoing communication, information sharing, and care coordination take place between medical and mental health providers.
As described in Screening and Diagnosis, screen patients for co-occurring psychiatric disorders common among people with OUD (or re-screen them if time has passed since the initial screening). Screening for anxiety and depression is recommended by the U.S. Preventive Services Taskforce,5 and can be more informative than simply asking the patient. Common co-occurring disorders with SUD with screening tools are as follows:
- Depression:
- Data Element: Patient Health Questionnaire 9 item (PHQ-9) total score [Reported] (2001) - 9-item questionnaire with a suicide risk screening, or
- Form: Patient Health Questionnaire-2 (PHQ-2) (2015) - 2-item questionnaire without a suicide risk screening;
- Anxiety: Generalized Anxiety Disorder 2-item (GAD-2) - Mental Health Screening - National HIV Curriculum, or Generalized Anxiety Disorder 7-item (GAD-7) scale; and
- Post-Traumatic Stress Disorder (PTSD): Primary Care PTSD Screen for DSM-5 (PC-PTSD-5) - PTSD: National Center for PTSD (2015).
For patients who screen positive for mental health symptoms, consider referring for counseling and other psychosocial supports and, if indicated, prescribing psychiatric medications. Even if a patient does not meet criteria for a psychiatric disorder, they may benefit from counseling and other supports.
In addition, ask your patients whether they have current problems or concerns that they think counseling or extra support might help.25 If they indicate an interest or willingness to engage in mental health services or other supports, refer the patient based on their unique needs, preferences, challenges,156 affordability, and availability of services. If your practice has made progress toward integrating behavioral health services you may already have relevant professionals as part of the care team, either internally or through well-established collaboration. Note also that there are digital therapeutics available that have been found to be effective in symptom reduction, either on their own or in combination with in-person or virtual therapies.8 Not every patient will need intensive mental health services, but such services may help address the underlying causes of the addiction and promote positive behavior change, particularly among those struggling to meet their treatment goals.
One patient with OUD shared,
"My only regret with buprenorphine] is that I didn't try it sooner. My advice to anyone that is struggling with an addiction is to give it a try. I also believe that therapy is a very important part of recovery."9
Common categories of support include:
- Mental health therapy or counseling, which can include individual, group, or family sessions;
- Substance use counseling, which can also include individual, group, or family sessions;
- Peer support services and self-help groups, such as Alcoholics Anonymous, SMART Recovery, and Narcotics Anonymous (These meetings are typically free or request an optional, discretionary contribution. Prescreening is suggested as some programs staunchly disapprove of the use of medications for OUD, so they would not be appropriate. Note that virtual self-help groups are also becoming more widely available); and
- Case or care management, which is particularly helpful for patients with health-related social needs such as safe housing, food assistance, education/employment, transportation, childcare, and so forth.
- Motivational Interviewing (MI): This evidence-based series of techniques or brief intervention aims to help individuals resolve ambivalence toward making behavior changes. MI requires providers to be supportive and empathic to help patients build confidence and optimism in their ability to change. To learn more, see Resources.
- Cognitive Behavioral Therapy (CBT): This method is one of the most used evidence-based approaches in mental health treatment. CBT helps patients identify their problem behaviors and triggers for substance misuse and teaches them skills and coping strategies to manage cravings and high-risk situations.
- Contingency Management (CM): This evidence-based approach involves programs providing patients with rewards (e.g., cash voucher or prize) to reinforce positive behaviors such as abstinence and treatment engagement.
- Family Therapy: Support from and healthy relationships with family members as well as a safe, stable living environment can be key to an individual's recovery. Family therapy can help address not only the individual's substance use, but also other underlying issues with co-occurring mental health disorders; family conflict; and other health-related social needs such as employment and housing. Family-based approaches can also be particularly important when treating adolescents.
- Mobile Apps: Internet-based or mobile apps, such as Reset-O, DynamiCare, WEconnect, and OARS incorporate CM and CBT strategies to support recovery. Other apps, such as CHESS Health, have a more comprehensive array of supports such as CBT, coaching, peer groups, and education. See the Integration Academy Topic Brief on Behavioral Health Apps in Primary Care for a discussion of the use of apps, including pros and cons. Note that there is some recent evidence that these tools can improve treatment outcomes.10
- Recovery Supports: People with OUD are more likely to have experienced a trauma, with rates exceeding 80%.11 Sex differences have been observed in the types of traumas experienced, response to trauma, rates of PTSD, and treatment response.12,13 Patients' experience with trauma may affect how they engage in care. See the Integrate Trauma-informed Care section for more information. There has been a growing use of peer recovery specialists, who can play a crucial role in treatment for OUD by providing support and guidance based on their own lived experiences with recovery. They offer emotional support and mentorship, serving as positive role models and sharing their recovery journeys to inspire hope and demonstrate that recovery is possible.14 Additionally, they educate individuals about medications for OUD, dispelling myths and misconceptions, and advocate for patients' needs within the healthcare system.15 While there is a need for additional research on the impact peer recovery specialists on medication adherence for OUD, incorporating peer support services into primary care treatment is an accessible and increasingly utilized way to engage and retain patients in recovery support.16,17
How Others Are Doing It
Help patients identify what types of services and supports would be most helpful to them at this time.
Identify Programs and Providers: As you begin providing medications for OUD, develop and maintain a list of resources for external mental health, substance use, community,58 and telehealth supports. Include opioid treatment programs (OTPs) and other programs across levels of care and treatment settings. If possible, establish collaborative working relationships with external providers, a relationship that specifically addresses areas such as communication, information sharing, and care coordination. Refer here for more information on Creating a Memorandum of Agreement | SAMHSA.
It is also important to identify locally available community-based services and recovery supports. Some patients may hesitate to follow up on working with external substance use treatment counselors but may be open to peer recovery support groups such as Alcoholics Anonymous, Narcotics Anonymous, or Self-Management and Recovery Training.1 Learn more about Community-Based and Recovery Supports. It is important to be aware that some recovery support groups may have negative attitudes toward medications for OUD, and patients may want to avoid those groups.
Some communities, particularly in rural areas, may have a shortage of mental health providers or recovery support groups. In these situations, explore telehealth options or phone or web-based apps.
Connect Patients to External Providers: A whole-person approach to connecting a patient to an external mental health clinician includes1:
- Obtaining patient consent to share information;
- Considering patient needs and preferences (e.g., program availability, eligibility, and affordability);
- Actively connecting patients with external providers (e.g., calling the program on behalf of the patient to make a connection as opposed to providing a phone number to follow up with); and
- Following up to determine if the patient connected with and worked with the external provider and what the outcomes were.
Ongoing care coordination can facilitate successful patient outcomes when working with external mental health providers.18 Create processes to work with external providers to coordinate care. Upon referring a patient, reach out to the external provider for an initial conversation about the patient's needs and progress with treatment, including medications for OUD and any other treatment they receive. This step can go a long way to help build a relationship with the external provider. Ideally, rather than relying on written progress notes or shared records, the whole care team of internal and external providers will have direct communication, or even meetings or "huddles" if feasible, to discuss the appropriateness of the treatment plan and adjust as needed.
See the Care Coordination and Patient Referral Sources section for more information.
Understand the limits on sharing information and records with external providers as well as requirements for patient consent. Establish ground rules about information sharing and care coordination and share them with the patient to retain trust. See General Operations.
Connect Patients to Internal Providers: If your practice has taken steps to integrate behavioral health and primary care, you may have behavioral health providers as part of the care team. Develop or adapt a process to connect patients receiving medications for OUD to mental health services. Establish clear workflows for communications, information sharing, and care coordination. Documentation in the common medical record is key to integrating and coordinating care.
Whenever possible, do a warm handoff between medical and behavior health staff, in which one provider directly introduces the patient to the other provider. Warm handoffs can help facilitate communication between providers, build relationships, and ensure referrals are not lost to follow-up. Relationships are fundamental to quality care. The goal is for the patient to see mental health services as one integrated dimension of their overall care for OUD, not as a separate and parallel health problem or treatment regimen.
Mental health services may be integrated into primary care through a variety of models. Examples include:
- Collaborative Care: In this model, primary care treatment for patients with comorbid mental health disorders is enhanced by adding care management to monitor patients between visits and regular review of patient progress by a mental health clinician. Care management and consulting psychiatry can be provided either onsite or remotely. Extensive evidence shows the effectiveness of this model, and it can be very cost-effective as it stretches scarce mental health staffing resources.19
- Mental Health Consultant: This model, sometimes also called the Primary Care Behavioral Health (PCBH) model, includes a licensed clinician, typically onsite, who works as part of the care team with the medical staff and is available for warm handoffs and huddles.20
Note that the consulting psychiatrist or mental health clinician may not have the expertise to consult on issues related to opioid and other SUDs. You may need to supplement with additional addictions expertise or develop in-house expertise. Finally, capacity issues can surface when expanding a service model's scope. Consider where the practice and its internal service capacity fits along the continuum of OUD care to determine which patients to refer elsewhere.
- Don't withhold medication if a patient is not ready to engage in counseling or recovery supports. (Similarly, don't withhold counseling or therapy if a patient is not ready to start MOUD.)
- Don't use a “one-size fits all” approach to evidence-based mental health counseling techniques. Adapt your strategies to the patient's needs and preferences.
- Don't assume that mental health services should only be provided by dedicated mental health providers. Strategies to help patients achieve behavior change, like motivational interviewing, are useful across provider types and disciplines.
- Don't assume every person with OUD will benefit from or want mental health services; don't require them for recovery.
FindTreatment.gov: Home
Medications for Opioid Use Disorder Treatment Protocol TIP 63 (updated 2021)
TAP 21: Addiction Counseling Competencies
Opioid ECHO
Penn State Project ECHO Current Topics
Project ECHO Trainings and Support
Motivational Interviewing Strategies and Techniques: Rationales and Examples
Describes the key principles of motivational interviewing and provides examples for how to use these techniques.
Motivational Interviewing: Talking with Someone Struggling with Opioid Use Disorder
Advisory: Using Motivational Interviewing in Substance Use Disorder Treatment
1. Substance Abuse and Mental Health Services Administration. TIP 63: Medications for Opioid Use Disorder. SAMHSA; 2021. Accessed April 7, 2025. https://library.samhsa.gov/product/tip-63-medications-opioid-use-disorder/pep21-02-01-002
2. Jones CM, McCance-Katz EF. Co-occurring substance use and mental disorders among adults with opioid use disorder. Drug and Alcohol Dependence. 2019;197:78-82. doi:10.1016/j.drugalcdep.2018.12.030
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7. Substance Abuse and Mental Health Services Administration. TIP 63: Medications for Opioid Use Disorder. SAMHSA Library. 2021. Accessed April 7, 2025. https://library.samhsa.gov/product/tip-63-medications-opioid-use-disorder/pep21-02-01-002
8. Peterson Health Technology Institute. Virtual Solutions for Mental Health Improve Symptoms and Expand Access, but Some Tools Come with High Costs. 2025. Accessed June 3, 2025. https://phti.org/announcement/virtual-solutions-for-mental-health-improve-symptoms-and-expand-access-but-some-tools-come-with-high-costs/
9. Tesani R de L. How Stigma Affects Patients Seeking Help for Drug Addiction. World Journal of Nursing Research. Published online 2025:31-46. doi:10.31586/wjnr.2025.1272
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12. Brown S. A Whole-Person Approach to Harm Reduction for Women. J Law Med Ethics. 2024;52(1):45-51. doi:10.1017/jme.2024.58
13. Substance Abuse and Mental Health Services Administration. Addressing the Specific Needs of Women for Treatment of Substance Use Disorders. SAMHSA; 2021. Accessed April 28, 2025. https://library.samhsa.gov/sites/default/files/pep20-06-04-002.pdf
14. Mercer F, Miler JA, Pauly B, et al. Peer Support and Overdose Prevention Responses: A Systematic “State-of-the-Art” Review. Int J Environ Res Public Health. 2021;18(22). doi:10.3390/ijerph182212073
15. Moffitt T, Fallin-Bennett A, Fanucchi L, et al. The development of a recovery coaching training curriculum to facilitate linkage to and increase retention on medications for opioid use disorder. Front Public Health. 2024;12:1334850. doi:10.3389/fpubh.2024.1334850
16. Gormley MA, Pericot-Valverde I, Diaz L, et al. Effectiveness of peer recovery support services on stages of the opioid use disorder treatment cascade: A systematic review. Drug Alcohol Depend. 2021;229(Pt B):109123. doi:10.1016/j.drugalcdep.2021.109123
17. Giraldo A, Shah P, Zerbo E, Nyaku AN. The role of recovery peer navigators in retention in outpatient buprenorphine treatment: a retrospective cohort study. Ann Med. 2024;56(1):2355566. doi:10.1080/07853890.2024.2355566
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20. American Psychological Association. Behavioral Health Integration Fact Sheet. Published online 2022. Accessed June 5, 2025. https://www.apa.org/health/behavioral-health-factsheet.pdf