Literature Collection

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Opioids & SU

The Literature Collection contains over 10,000 references for published and grey literature on the integration of behavioral health and primary care. Learn More

Use the Search feature below to find references for your terms across the entire Literature Collection, or limit your searches by Authors, Keywords, or Titles and by Year, Type, or Topic. View your search results as displayed, or use the options to: Show more references per page; Sort references by Title or Date; and Refine your search criteria. Expand an individual reference to View Details. Full-text access to the literature may be available through a link to PubMed, a DOI, or a URL. References may also be exported for use in bibliographic software (e.g., EndNote, RefWorks, Zotero).

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5721
Maintenance agonist treatments for opiate-dependent pregnant women
Type: Journal Article
Authors: S. Minozzi, L. Amato, S. Jahanfar, C. Bellisario, M. Ferri, M. Davoli
Year: 2020
Publication Place: England
Topic(s):
Healthcare Disparities See topic collection
,
Measures See topic collection
,
Opioids & Substance Use See topic collection
5722
Maintenance medication for opiate addiction: The foundation of recovery
Type: Journal Article
Authors: G. Bart
Year: 2012
Publication Place: England
Abstract: Illicit use of opiates is the fastest growing substance use problem in the United States, and the main reason for seeking addiction treatment services for illicit drug use throughout the world. It is associated with significant morbidity and mortality related to human immunodeficiency virus, hepatitis C, and overdose. Treatment for opiate addiction requires long-term management. Behavioral interventions alone have extremely poor outcomes, with more than 80% of patients returning to drug use. Similarly poor results are seen with medication-assisted detoxification. This article provides a topical review of the three medications approved by the Food and Drug Administration for long-term treatment of opiate dependence: the opioid-agonist methadone, the partial opioid-agonist buprenorphine, and the opioid-antagonist naltrexone. Basic mechanisms of action and treatment outcomes are described for each medication. Results indicate that maintenance medication provides the best opportunity for patients to achieve recovery from opiate addiction. Extensive literature and systematic reviews show that maintenance treatment with either methadone or buprenorphine is associated with retention in treatment, reduction in illicit opiate use, decreased craving, and improved social function. Oral naltrexone is ineffective in treating opiate addiction, but recent studies using extended-release naltrexone injections have shown promise. Although no direct comparisons between extended-release naltrexone injections and either methadone or buprenorphine exist, indirect comparison of retention shows inferior outcome compared with methadone and buprenorphine. Further work is needed to directly compare each medication and determine individual factors that can assist in medication selection. Until such time, selection of medication should be based on informed choice following a discussion of outcomes, risks, and benefits of each medication.
Topic(s):
Opioids & Substance Use See topic collection
,
Healthcare Policy See topic collection
5723
Major depression in primary care: making the diagnosis
Type: Journal Article
Authors: C. W. Ng, C. H. How, Y. P. Ng
Year: 2016
Publication Place: Singapore
Topic(s):
Medically Unexplained Symptoms See topic collection
5724
Major depression, depression treatment and quality of primary medical care
Type: Journal Article
Authors: B. G. Druss, K. Rask, W. J. Katon
Year: 2008
Publication Place: United States
Abstract: OBJECTIVE: This study investigated the association between diagnosis of major depression, treatment for major depression and receipt of appropriate primary medical care. METHOD: As part of the 1999 National Health Interview Survey, a nationally representative sample of 30,801 adults was administered the Composite International Diagnostic Interview - Short Form. Multivariate analyses examined the association between 12-month major depression and each of the four cardinal features of primary care (access, comprehensiveness, coordination and continuity) stratified by whether depressed individuals received care for depression in primary care, specialty mental health care or no treatment. RESULTS: Overall, persons with depression had statistically significant problems in all four domains of primary care (8/10 indicators in total). However, patterns differed substantially based on depression treatment status. Persons with untreated depression had difficulties in access to (3/3 measures) and comprehensiveness of (5/5 measures) care, but not with coordination (0/1 measure) and continuity (0/1 measure). In contrast, persons with depression who received specialty treatment had more difficulties in coordination (1/1 measure) and continuity (1/1 measure) of primary care. Persons treated for depression in primary care reported the least difficulties in any of the four domains of primary care (0/10 measures). CONCLUSIONS: Major depression was associated with significant challenges in receipt of primary care; however, these problems varied based on whether and where depression treatment is received.
Topic(s):
Education & Workforce See topic collection
5726
Major depressive disorder, somatic pain, and health care costs in an urban primary care practice
Type: Journal Article
Authors: M. J. Gameroff, M. Olfson
Year: 2006
Publication Place: United States
Abstract: OBJECTIVE: To evaluate the extent to which pain severity contributes to the increased medical care costs associated with depression in primary care. METHOD: A systematic sample of primary care patients (N = 1028) from an urban practice were assessed between April 1, 2002, and January 16, 2003, with the DSM-IV Primary Care Evaluation of Mental Disorders Patient Health Questionnaire, the Sheehan Disability Scale, a medical illness checklist, and the Medical Outcomes Study 12-Item Short Form Health Survey, which includes a measure of pain interference with daily activities. Medical charges for inpatient, outpatient, and emergency department services were assessed for the 6-month periods preceding and following the index medical visit. Patients with and without major depressive disorder (MDD) were first compared with respect to clinical characteristics and median medical charges. Mean predicted medical care charges were then compared among 4 patient groups: (1) No MDD/ Low Pain Interference, (2) No MDD/High Pain Interference, (3) MDD/Low Pain Interference, and (4) MDD/High Pain Interference. RESULTS: As compared to patients without MDD (N = 821), those with MDD (N = 207) had significantly higher predicted mean medical care charges (19,838 dollars vs. 6268 dollars; t = 3.3, p = .001) after controlling for age and gender and were significantly more likely to report at least moderate pain-related interference in daily activities (MDD: 69.1% vs. no MDD: 38.6%; chi 2 = 61.3, df = 1, p < .0001). Mean predicted medical care charges of patients with MDD and at least moderate pain-related interference were on average 2.33 times (95% CI = 1.34 to 4.05) as high as those for patients with MDD and little or no pain-related interference. Among patients with at least moderate pain-related interference, MDD was associated with significantly greater mean predicted charges (mean = 28,598 dollars/ year with MDD vs. 11,031 dollars/year without MDD). However, among patients with lower levels of pain-related interference, MDD was not associated with greater mean predicted medical charges (mean = 2306 dollars/year with MDD vs. 3560 dollars/year without MDD). CONCLUSION: In this urban primary care practice, major depressive disorder is associated with increased health care costs, but only among patients with moderate to extreme pain-related interference in daily activities.
Topic(s):
Financing & Sustainability See topic collection
5727
Making community pharmacies psychologically informed environments (PIE): a feasibility study to improve engagement with people using drug services in Scotland
Type: Journal Article
Authors: C. Matheson, C. Hunter, J. Schofield, K. O'Sullivan, J. Hunter, A. Munro, T. Parkes
Year: 2023
Abstract:

AIM: This developmental study tested the feasibility of training pharmacy staff on the psychologically informed environments (PIE) approach to improve the delivery of care. BACKGROUND: Community pharmacies provide key services to people who use drugs (PWUD) through needle exchange services, medication-assisted treatment and naloxone distribution. PWUD often have trauma backgrounds, and an approach that has been demonstrated to work well in the homeless sector is PIEs. METHODS: Bespoke training was provided by clinical psychologists and assessed by questionnaire. Staff interviews explored changes made following PIE training to adapt the delivery of care. Changes in attitude of staff following training were assessed by questionnaire. Peer researchers interviewed patient/client on observed changes and experiences in participating pharmacies. Staff interviews were conducted six months after training to determine what changes, if any, staff had implemented. Normalisation process theory (NPT) provided a framework for assessing change. FINDINGS: Three pharmacies (16 staff) participated. Training evaluation was positive; all participants rated training structure and delivery as 'very good' or 'excellent'. There was no statistically significant change in attitudes. COVID-19 lockdowns restricted follow-up data collection. Staff interviews revealed training had encouraged staff to reflect on their practice and communication and consider potentially discriminatory practice. PIE informed communication skills were applied to manage COVID-19 changes. Staff across pharmacies noted mental health challenges for patients. Five patients were interviewed but COVID-19 delays in data collection meant changes in delivery of care were difficult to recall. However, they did reflect on interactions with pharmacy staff generally. Across staff and patient interviews, there was possible conflation of practice changes due to COVID-19 and the training. However, the study found that training pharmacy teams in PIE was feasible, well received, and further development is recommended. There was evidence of the four NPT domains to support change (coherence, cognitive participation, collective action and reflexive monitoring).

Topic(s):
Education & Workforce See topic collection
,
Opioids & Substance Use See topic collection
,
Healthcare Disparities See topic collection
5728
Making Harm Reduction More Accessible: Fentanyl Test Strip Awareness and Attitudes among Emergency Department Patients Who Use Drugs
Type: Journal Article
Authors: M. K. Reed, A. Siegler, Esteves Camacho, K. London, K. Schaeffer, K. L. Rising
Year: 2024
Abstract:

BACKGROUND: Fentanyl test strips (FTS) are a harm reduction method for people to test their drugs for fentanyl. Ideal points for FTS distribution have not been identified. Many people who use drugs have frequent contact with the Emergency Department (ED). We piloted FTS distribution in two urban hospital EDs. METHODS: Between June-December 2021 in Philadelphia, PA, patients with past 30-day drug use completed a survey about drug use, fentanyl attitudes, and FTS; then offered FTS and a brief training. Survey data were analyzed using SPSS for bivariate statistics. RESULTS: Patients (n = 135) were primarily White (68.1%) and male (72.6%). Participants regularly interacted with substance use (57.8%) and benefits coordination (49.6%) services. The most common drugs used were heroin/fentanyl (68.9%), crack cocaine (45.2%) and cannabis (40.0%). Most (98.5%) had heard of fentanyl though few (18.5%) had ever used FTS. Across most drug types, participants were concerned about fentanyl. All accepted FTS training and distribution. Few (9.6%) were somewhat or very concerned about having FTS if stopped by police and this number varied by race (7.6% of White people were somewhat or very concerned, compared to 12.8% of Black people). Most participants were already engaged in risk reduction practices. DISCUSSION: FTS are a widely desired harm reduction tool to facilitate informed decision-making, and non-harm reduction locations are potentially feasible and acceptable distribution sites. Given regular contact with EDs and social services across the sample, FTS should be offered at non-harm reduction locations that come into frequent contact with people who use drugs.

Topic(s):
Opioids & Substance Use See topic collection
,
Education & Workforce See topic collection
5729
Making measurement‐based care for addictions a reality in primary care
Type: Journal Article
Authors: Katharine A. Bradley, Ryan M. Caldeiro, Kevin A. Hallgren, Daniel R. Kivlahan
Year: 2019
Publication Place: Malden, Massachusetts
Topic(s):
Education & Workforce See topic collection
,
Opioids & Substance Use See topic collection
5730
Making room for mental health in the medical home
Type: Journal Article
Authors: M. F. Hogan, L. I. Sederer, T. E. Smith, I. R. Nossel
Year: 2010
Publication Place: United States
Abstract: Discussions of health care reform emphasize the need for coordinated care, and evidence supports the effectiveness of medical home and integrated delivery system models. However, mental health often is left out of the discussion. Early intervention approaches for children and adolescents in primary care are important given the increased rates of detection of mental illness in youth. Most adults also receive treatment for mental illness from nonspecialists, underscoring the role for mental health in medical home models. Flexible models for coordinated care are needed for people with serious mental illness, who have high rates of comorbid medical problems. Programs implemented in the New York State public mental health system are examples of efforts to better coordinate medical and mental health services.
Topic(s):
Key & Foundational See topic collection
,
Medical Home See topic collection
,
Healthcare Policy See topic collection
5731
Making sense of meaningful use stage 2: second wave or tsunami?
Type: Journal Article
Authors: J. Mitchell, S. E. Waldren
Year: 2014
Publication Place: United States
Topic(s):
HIT & Telehealth See topic collection
5732
Making the Case for Primary Care and Mandated Suicide Prevention Education
Type: Journal Article
Authors: Jennifer Stuber, Paul Quinnett
Year: 2013
Topic(s):
Education & Workforce See topic collection
5733
Malmo Treatment Referral and Intervention Study (MATRIS) -- effective referral from syringe exchange to treatment for heroin dependence: A pilot randomized controlled trial.
Type: Journal Article
Authors: Martin Braback, Suzan Nilsson, Pernilla Isendahl, Katja Troberg, Louise Bradvik, Anders Hakansson
Year: 2016
Topic(s):
Opioids & Substance Use See topic collection
5734
Managed behavioral health care: Lessons from Massachusetts
Type: Journal Article
Authors: Donald S. Shepard, Marilyn C. Daley, Richard H. Beinecke, Clare L. Hurley
Year: 2005
Publication Place: Germany: Springer
Topic(s):
Financing & Sustainability See topic collection
5735
Managed care and children's behavioral health services in Massachusetts
Type: Journal Article
Authors: B. Dickey, S. L. Normand, E. C. Norton, A. Rupp, H. Azeni
Year: 2001
Publication Place: United States
Abstract: OBJECTIVE: The authors investigated changes in treatment patterns and costs of care for children after the implementation of the Massachusetts Medicaid carve-out managed care plan. METHODS: The authors hypothesized that after the introduction of managed care, per-child expenditures would be reduced, continuity of care would not improve, and per-child mental health expenditures would undergo larger reductions for disabled children, compared with children enrolled in the Aid to Families With Dependent Children program. Using data from Medicaid and the Massachusetts Department of Mental Health, the authors studied 16,664 Massachusetts Medicaid beneficiaries aged one to 17 years for whom reimbursement claims were submitted for psychiatric or substance use disorder treatment at least once during the two years before the introduction of managed care (1991 to 1992) or during the two years afterward (1994 to 1995). Multivariate analysis was used to estimate changes in probability of admission, and, among patients admitted, to identify factors accounting for variation in length of stay. To assess the variation in expenditures, we regressed the same variables, using the natural logarithm function to transform total mental health expenditures data and inpatient expenditures data to reduce skewness. RESULTS: After the introduction of managed care, per-child expenditures were lower, especially for disabled children, and the Department of Mental Health was used as a safety net for the most seriously ill children without increasing state expenditures. Continuity of care appeared to decline for disabled children. CONCLUSIONS: It is likely that a combination of factors related to the reported changes in patterns of care and expenditures were responsible for the overall per-child expenditures.
Topic(s):
Financing & Sustainability See topic collection
,
Healthcare Policy See topic collection
5736
Managed care, access to mental health specialists, and outcomes among primary care patients with depressive symptoms
Type: Journal Article
Authors: David E. Grembowski, Diane Martin, Donald L. Patrick, Paula Diehr, Wayne Katon, Barbara Williams, Ruth Engelberg, Louise Novak, Deborah Dickstein, Richard Deyo, Harold I. Goldberg
Year: 2002
Publication Place: United Kingdom: Blackwell Publishing
Topic(s):
Financing & Sustainability See topic collection
5737
Management and monitoring of opioid use in pregnancy
Type: Journal Article
Authors: N. L. K. Rausgaard, I. O. Ibsen, J. S. Jørgensen, R. F. Lamont, P. Ravn
Year: 2020
Publication Place: United States
Topic(s):
Healthcare Disparities See topic collection
,
Opioids & Substance Use See topic collection
5738
Management of Acute Postpartum Pain in Patients Maintained on Methadone or Buprenorphine During Pregnancy
Type: Journal Article
Authors: Hendree E. Jones, Kevin O'Grady, Jennifer Dahne, Rolley Johnson, Laetitia Lemoine, Lorriane Milio, Alice Ordean, Peter Selby
Year: 2009
Topic(s):
Opioids & Substance Use See topic collection
5739
Management of comorbid mental and somatic disorders in stepped care approaches in primary care: a systematic review
Type: Journal Article
Authors: K. Maehder, B. Lowe, M. Harter, D. Heddaeus, M. Scherer, A. Weigel
Year: 2019
Publication Place: England
Abstract: Background: Stepped care models comprise a graded treatment intensity and a systematic monitoring. For an effective implementation, stepped care models have to account for the high rates of mental and somatic comorbidity in primary care. Objectives: The aim of the systematic review was to take stock of whether present stepped care models take comorbidities into consideration. A further aim was to give an overview on treatment components and involved health care professionals. Methods: A systematic literature search was performed using the databases PubMed, PsycINFO, Cochrane Library and Web of Science. Selection criteria were a randomized controlled trial of a primary-care-based stepped care intervention, adult samples, publication between 2000 and 2017 and English or German language. Results: Of 1009 search results, 39 studies were eligible. One-third of the trials were conceived for depressive disorders only, one-third for depression and further somatic and/or mental comorbidity and one-third for conditions other than depression. In 39% of the studies comorbidities were explicitly integrated in treatment, mainly via transdiagnostic self-management support, interprofessional collaboration and digital approaches for treatment, monitoring and communication. Most care teams were composed of a primary care physician, a care manager and a psychiatrist and/or psychologist. Due to the heterogeneity of the addressed disorders, no meta-analysis was performed. Conclusions: Several stepped care models in primary care already account for comorbidities, with depression being the predominant target disorder. To determine their efficacy, the identified strategies to account for comorbidities should be investigated within stepped care models for a broader range of disorders.
Topic(s):
Medically Unexplained Symptoms See topic collection
5740
Management of depression for people with cancer (SMaRT oncology 1):
Type: Journal Article
Authors: V. Strong, R. Waters, C. Hibberd, G. Murray, L. Wall, J. Walker, G. McHugh, A. Walker, M. Sharpe
Year: 2008
Abstract: Abstract. BACKGROUND: Major depressive disorder severely impairs the quality of life of patients with medical disorders such as cancer, but evidence to guide its management is scarce. We aimed to assess the efficacy and cost of a nurse-delivered complex intervention that was designed to treat major depressive disorder in patients who have cancer. METHODS: We did a randomised trial in a regional cancer centre in Scotland, UK. 200 outpatients who had cancer with a prognosis of greater than 6 months and major depressive disorder (identified by screening) were eligible and agreed to take part. Their mean age was 56.6 (SD 11.9) years, and 141 (71%) were women. We randomly assigned 99 of these participants to usual care, and 101 to usual care plus the intervention, with minimisation for sex, age, diagnosis, and extent of disease. The intervention was delivered by a cancer nurse at the centre over an average of seven sessions. The primary outcome was the difference in mean score on the self-reported Symptom Checklist-20 depression scale (range 0 to 4) at 3 months after randomisation. Analysis was by intention to treat. This trial is registered as ISRCTN84767225. FINDINGS: Primary outcome data were missing for four patients. For 196 patients for whom we had data at 3 months, the adjusted difference in mean Symptom Checklist-20 depression score, between those who received the intervention and those who did not, was 0.34 (95% CI 0.13-0.55). This treatment effect was sustained at 6 and 12 months. The intervention also improved anxiety and fatigue but not pain or physical functioning. It cost an additional pound sterling 5278 (US$10 556) per quality-adjusted life-year gained. INTERPRETATION: The intervention-Depression Care for People with Cancer-offers a model for the management of major depressive disorder in patients with cancer and other medical disorders who are attending specialist medical services that is feasible, acceptable, and potentially cost effective.
Topic(s):
Financing & Sustainability See topic collection