TY - JOUR KW - Adult KW - Analgesics, Opioid/administration & dosage/adverse effects KW - Drug Overdose/prevention & control/psychology KW - Female KW - Harm Reduction KW - Health Education/methods KW - Health Knowledge, Attitudes, Practice KW - Humans KW - Interviews as Topic KW - Male KW - Multivariate Analysis KW - Naloxone/administration & dosage KW - Narcotic Antagonists/administration & dosage KW - Opioid-Related Disorders/prevention & control KW - Program Evaluation KW - Regression Analysis KW - Risk Factors KW - Spain AU - Albert Espelt AU - Marina Bosque-Prous AU - Cinta Folch AU - Ana Sarasa-Renedo AU - Xavier Majo AU - Jordi Casabona AU - Teresa Brugal AU - REDAN Group A1 - AB - The objectives were to analyze the knowledge about overdose prevention, the use of naloxone, and the number of fatal overdoses after the implementation of Systematic Training in Overdose Prevention (STOOP) program. We conducted a quasi-experimental study, and held face-to-face interviews before (n = 725) and after (n = 722) implementation of systematic training in two different samples of people who injected opioids attending harm reduction centers. We asked participants to list the main causes of overdose and the main actions that should be taken when witnessing an overdose. We created two dependent variables, the number of (a) correct and (b) incorrect answers. The main independent variable was Study Group: Intervention Group (IG), Comparison Group (CG), Pre-Intervention Group With Sporadic Training in Overdose Prevention (PREIGS), or Pre-Intervention Group Without Training in Overdose Prevention (PREIGW). The relationship between the dependent and independent variables was assessed using a multivariate Poisson regression analysis. Finally, we conducted an interrupted time series analysis of monthly fatal overdoses before and after the implementation of systematic program during the period 2006-2015. Knowledge of overdose prevention increased after implementing systematic training program. Compared to the PREIGW, the IG gave more correct answers (IRR = 1.40;95%CI:1.33-1.47), and fewer incorrect answers (IRR = 0.33;95%CI:0.25-0.44). Forty percent of people who injected opioids who received a naloxone kit had used the kit in response to an overdose they witnessed. These courses increase knowledge of overdose prevention in people who use opioids, give them the necessary skills to use naloxone, and slightly diminish the number of fatal opioid overdoses in the city of Barcelona. AD - Agencia de Salut Publica de Barcelona, Placa Lesseps, Barcelona, Spain.; Centros de Investigacion Biomedica en Red. Epidemiologia y Salud Publica (CIBERESP), Calle Melchor Fernandez Almagro, Madrid, Spain.; Facultat de Ciencies de la Salut de Manresa, Universitat de Vic Universitat Central de Catalunya (UVicUCC), Av. Universitaria, Manresa, Spain.; Departament de Psicobiologia i Metodologia en Ciencies de la Salut, Universitat Autonoma de Barcelona, Campus UAB, Bellaterra, Spain.; Agencia de Salut Publica de Barcelona, Placa Lesseps, Barcelona, Spain.; Centre d'Estudis Epidemiologics sobre les Infeccions de Transmissio Sexual i Sida de Catalunya (CEEISCAT), Agencia de Salut Publica de Catalunya (ASPC), Generalitat de Catalunya, Carretera Canyet s/n, Badalona, Spain.; Agencia de Salut Publica de Barcelona, Placa Lesseps, Barcelona, Spain.; Programa de Epidemiologia Aplicada y de Campo (PEAC), Instituto de Salud Carlos III, Calle Sinesio Delgado, Madrid, Spain.; Subdireccio General de Drogodependencies, Departament de Salut de la Generalitat de Catalunya, Carrer de Roc Boronat, Barcelona, Spain.; Subdireccio General de Drogodependencies, Departament de Salut de la Generalitat de Catalunya, Carrer de Roc Boronat, Barcelona, Spain.; Agencia de Salut Publica de Barcelona, Placa Lesseps, Barcelona, Spain. BT - PloS one C5 - Education & Workforce; Opioids & Substance Use CP - 10 CY - United States DO - 10.1371/journal.pone.0186833 IS - 10 JF - PloS one LA - eng M1 - Journal Article N2 - The objectives were to analyze the knowledge about overdose prevention, the use of naloxone, and the number of fatal overdoses after the implementation of Systematic Training in Overdose Prevention (STOOP) program. We conducted a quasi-experimental study, and held face-to-face interviews before (n = 725) and after (n = 722) implementation of systematic training in two different samples of people who injected opioids attending harm reduction centers. We asked participants to list the main causes of overdose and the main actions that should be taken when witnessing an overdose. We created two dependent variables, the number of (a) correct and (b) incorrect answers. The main independent variable was Study Group: Intervention Group (IG), Comparison Group (CG), Pre-Intervention Group With Sporadic Training in Overdose Prevention (PREIGS), or Pre-Intervention Group Without Training in Overdose Prevention (PREIGW). The relationship between the dependent and independent variables was assessed using a multivariate Poisson regression analysis. Finally, we conducted an interrupted time series analysis of monthly fatal overdoses before and after the implementation of systematic program during the period 2006-2015. Knowledge of overdose prevention increased after implementing systematic training program. Compared to the PREIGW, the IG gave more correct answers (IRR = 1.40;95%CI:1.33-1.47), and fewer incorrect answers (IRR = 0.33;95%CI:0.25-0.44). Forty percent of people who injected opioids who received a naloxone kit had used the kit in response to an overdose they witnessed. These courses increase knowledge of overdose prevention in people who use opioids, give them the necessary skills to use naloxone, and slightly diminish the number of fatal opioid overdoses in the city of Barcelona. PP - United States PY - 2017 SN - 1932-6203; 1932-6203 SP - e0186833 T1 - Is systematic training in opioid overdose prevention effective? T2 - PloS one TI - Is systematic training in opioid overdose prevention effective? U1 - Education & Workforce; Opioids & Substance Use U2 - 29088247 U3 - 10.1371/journal.pone.0186833 VL - 12 VO - 1932-6203; 1932-6203 Y1 - 2017 Y2 - Oct 31 ER -