Literature Collection

8141

Prospective association of anxiety, depressive, and addictive disorders with high utilization of primary, specialty and emergency medical care

Type: Journal Article

Authors: Julian D. Ford, Robert L. Trestman, Karen Steinberg, Howard Tennen, Scott Allen

Year: 2004

Publication Place: Netherlands: Elsevier Science

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8142

Prospective comparative assessment of buprenorphine overdose with heroin and methadone: Clinical characteristics and response to antidotal treatment.

Type: Journal Article

Authors: Bruno Megarbane, Anne Buisine, Frederic Jacobs, Dabor Resiere, Lucie Chevillard, Eric Vicaut, Frederic J. Baud

Year: 2010

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8143

Prospective drug safety monitoring using the UK primary-care General Practice Research Database: theoretical framework, feasibility analysis and extrapolation to future scenarios

Type: Journal Article

Authors: S. Johansson, M. A. Wallander, F. J. de Abajo, L. A. Garcia Rodriguez

Year: 2010

Publication Place: New Zealand

Abstract: BACKGROUND: Post-launch drug safety monitoring is essential for the detection of adverse drug signals that may be missed during preclinical trials. Traditional methods of postmarketing surveillance such as spontaneous reporting have intrinsic limitations, many of which can be overcome by the additional application of structured pharmacoepidemiological approaches. However, further improvement in drug safety monitoring requires a shift towards more proactive pharmacoepidemiological methods that can detect adverse drug signals as they occur in the population. OBJECTIVE: To assess the feasibility of using proactive monitoring of an electronic medical record system, in combination with an independent endpoint adjudication committee, to detect adverse events among users of selected drugs. METHODS: UK General Practice Research Database (GPRD) information was used to detect acute liver disorder associated with the use of amoxicillin/clavulanic acid (hepatotoxic) or low-dose aspirin (acetylsalicylic acid [non-hepatotoxic]). Individuals newly prescribed these drugs between 1 October 2005 and 31 March 2006 were identified. Acute liver disorder cases were assessed using GPRD computer records in combination with case validation by an independent endpoint adjudication committee. Signal generation thresholds were based on the background rate of acute liver disorder in the general population. RESULTS: Over a 6-month period, 8148 patients newly prescribed amoxicillin/clavulanic acid and 5577 patients newly prescribed low-dose aspirin were identified. Within this cohort, searches identified 11 potential liver disorder cases from computerized records: six for amoxicillin/clavulanic acid and five for low-dose aspirin. The independent endpoint adjudication committee refined this to four potential acute liver disorder cases for whom paper-based information was requested for final case assessment. Final case assessments confirmed no cases of acute liver disorder. The time taken for this study was 18 months (6 months for recruitment and 12 months for data management and case validation). To reach the estimated target exposure necessary to raise or rule out a signal of concern to public health, we determined that a recruitment period 2-3 times longer than that used in this study would be required. Based on the real market uptake of six commonly used medicinal products launched between 2001 and 2006 in the UK (budesonide/eformoterol [fixed-dose combination], duloxetine, ezetimibe, metformin/rosiglitazone [fixed-dose combination], tiotropium bromide and tadalafil) the target exposure would not have been reached until the fifth year of marketing using a single database. CONCLUSION: It is feasible to set up a system that actively monitors drug safety using a healthcare database and an independent endpoint adjudication committee. However, future successful implementation will require multiple databases to be queried so that larger study populations are included. This requires further development and harmonization of international healthcare databases.

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8144

Prospective Multicenter Observational Study of 260 Infants Born to 259 Opiate-Dependent Mothers on Methadone or High-Dose Buprenophine Substitution

Type: Journal Article

Authors: Claude Lejeune, Laurence Simmat-Durand, Laurent Gourarier, Sandrine Aubisson

Year: 2006

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8145

Prospects for Care Coordination Measurement Using Electronic Data Sources

Type: Government Report

Authors: K. M. McDonald, E. Schultz, T. Chapman, S. Davies, N. Pineda, J. Lonhar, E. Schmidt, S. Wilson

Year: 2012

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Disclaimer:

This grey literature reference is included in the Academy's Literature Collection in keeping with our mission to gather all sources of information on integration. Grey literature is comprised of materials that are not made available through traditional publishing avenues. Often, the information from unpublished resources can be limited and the risk of bias cannot be determined.

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8146

Protecting pain patients. The evaluation of a chronic pain educational intervention

Type: Journal Article

Authors: Simon Holliday, Chris Hayes, Adrian Dunlop, Simon Morgan, Amanda Tapley, Kim Henderson, Briony Larance, Parker Magin

Year: 2017

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8147

Protecting the Rights of Lesbian, Gay, Bisexual, Transgender, Queer, and Intersex (LGBTQI+) People

Type: Report

Authors: U.S. Department of Health and Human Services

Year: 2023

Publication Place: Washington, DC

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,

Disclaimer:

This grey literature reference is included in the Academy's Literature Collection in keeping with our mission to gather all sources of information on integration. Grey literature is comprised of materials that are not made available through traditional publishing avenues. Often, the information from unpublished resources can be limited and the risk of bias cannot be determined.

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8148

Protecting Youth Mental Health - The U.S. Surgeon General’s Advisory

Type: Web Resource

Authors: Office of the U.S. Surgeon General

Year: 2021

Publication Place: North Bethesda, MD

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, ,

Disclaimer:

This grey literature reference is included in the Academy's Literature Collection in keeping with our mission to gather all sources of information on integration. Grey literature is comprised of materials that are not made available through traditional publishing avenues. Often, the information from unpublished resources can be limited and the risk of bias cannot be determined.

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8149

Protocol for a mixed-methods feasibility study for the surviving opioid overdose with naloxone education and resuscitation (SOONER) randomised control trial

Type: Journal Article

Authors: A. Orkin, D. Campbell, C. Handford, S. Hopkins, M. Klaiman, P. Leece, J. A. Parsons, R. Shahin, C. Strike, K. Thorpe, K. Sellen, G. Milos, A. Wright, M. Charles, R. Sniderman, L. Morrison, SOONER Investigators

Year: 2019

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8150

Protocol for harmonization of randomized trials testing the addition of behavioral therapy to buprenorphine for opioid use disorder

Type: Journal Article

Authors: R. K. McHugh, A. J. Bailey, R. D. Weiss, G. M. Fitzmaurice

Year: 2024

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8151

Protocol for the implementation of a statewide mobile addiction program

Type: Journal Article

Authors: C. A. Tschampl, C. Regis, N. E. Johnson, M. T. Davis, D. Hodgkin, M. F. Brolin, E. Do, C. M. Horgan, T. C. Green, B. Reilly, M. Duska, E. M. Taveras

Year: 2023

Abstract:

With overdose deaths increasing, improving access to harm reduction and low barrier substance use disorder treatment is more important than ever. The Community Care in Reach(®) model uses a mobile unit to bring both harm reduction and clinical care for addiction to people experiencing barriers to office-based care. These mobile units provide many resources and services to people who use drugs, including safer consumption supplies, naloxone, medication for substance use disorder treatment, and a wide range of primary and preventative care. This protocol outlines the evaluation plan for the Community in Care(®) model in MA, USA. Using the RE-AIM framework, this evaluation will assess how mobile services engage new and underserved communities in addiction services and primary and preventative care.

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8152

Protocol of an ongoing randomized controlled trial of care management for comorbid depression and hypertension: the Chinese Older Adult Collaborations in Health (COACH) study

Type: Journal Article

Authors: S. Chen, Y. Conwell, J. Xue, L. W. Li, W. Tang, H. R. Bogner, H. Dong

Year: 2018

Publication Place: England

Abstract: BACKGROUND: Depression and hypertension are common, costly, and destructive conditions among the rapidly aging population of China. The two disorders commonly coexist and are poorly recognized and inadequately treated, especially in rural areas. METHODS: The Chinese Older Adult Collaborations in Health (COACH) Study is a cluster randomized controlled trial (RCT) designed to test the hypotheses that the COACH intervention, designed to manage comorbid depression and hypertension in older adult, rural Chinese primary care patients, will result in better treatment adherence and greater improvement in depressive symptoms and blood pressure control, and better quality of life, than enhanced Care-as-Usual (eCAU). Based on chronic disease management and collaborative care principles, the COACH model integrates the care provided by the older person's primary care provider (PCP) with that delivered by an Aging Worker (AW) from the village's Aging Association, supervised by a psychiatrist consultant. One hundred sixty villages, each of which is served by one PCP, will be randomly selected from two counties in Zhejiang Province and assigned to deliver eCAU or the COACH intervention. Approximately 2400 older adult residents from the selected villages who have both clinically significant depressive symptoms and a diagnosis of hypertension will be recruited into the study, randomized by the villages in which they live and receive primary care. After giving informed consent, they will undergo a baseline research evaluation; receive treatment for 12 months with the approach to which their village was assigned; and be re-evaluated at 3, 6, 9, and 12 months after entry. Depression and HTN control are the primary outcomes. Treatment received, health care utilization, and cost data will be obtained from the subjects' electronic medical records (EMR) and used to assess adherence to care recommendations and, in a preliminary manner, to establish cost and cost effectiveness of the intervention. DISCUSSION: The COACH intervention is designed to serve as a model for primary care-based management of common mental disorders that occur in tandem with common chronic conditions of later life. It leverages existing resources in rural settings, integrates social interventions with the medical model, and is consistent with the cultural context of rural life. TRIAL REGISTRATION: ClinicalTrials.gov ID: NCT01938963 ; First posted: September 10, 2013.

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8153

Protocol of an ongoing randomized controlled trial of care management for comorbid depression and hypertension: the Chinese Older Adult Collaborations in Health (COACH) study

Type: Journal Article

Authors: S. Chen, Y. Conwell, J. Xue, L. W. Li, W. Tang, H. R. Bogner, H. Dong

Year: 2018

Publication Place: England

Abstract: BACKGROUND: Depression and hypertension are common, costly, and destructive conditions among the rapidly aging population of China. The two disorders commonly coexist and are poorly recognized and inadequately treated, especially in rural areas. METHODS: The Chinese Older Adult Collaborations in Health (COACH) Study is a cluster randomized controlled trial (RCT) designed to test the hypotheses that the COACH intervention, designed to manage comorbid depression and hypertension in older adult, rural Chinese primary care patients, will result in better treatment adherence and greater improvement in depressive symptoms and blood pressure control, and better quality of life, than enhanced Care-as-Usual (eCAU). Based on chronic disease management and collaborative care principles, the COACH model integrates the care provided by the older person's primary care provider (PCP) with that delivered by an Aging Worker (AW) from the village's Aging Association, supervised by a psychiatrist consultant. One hundred sixty villages, each of which is served by one PCP, will be randomly selected from two counties in Zhejiang Province and assigned to deliver eCAU or the COACH intervention. Approximately 2400 older adult residents from the selected villages who have both clinically significant depressive symptoms and a diagnosis of hypertension will be recruited into the study, randomized by the villages in which they live and receive primary care. After giving informed consent, they will undergo a baseline research evaluation; receive treatment for 12 months with the approach to which their village was assigned; and be re-evaluated at 3, 6, 9, and 12 months after entry. Depression and HTN control are the primary outcomes. Treatment received, health care utilization, and cost data will be obtained from the subjects' electronic medical records (EMR) and used to assess adherence to care recommendations and, in a preliminary manner, to establish cost and cost effectiveness of the intervention. DISCUSSION: The COACH intervention is designed to serve as a model for primary care-based management of common mental disorders that occur in tandem with common chronic conditions of later life. It leverages existing resources in rural settings, integrates social interventions with the medical model, and is consistent with the cultural context of rural life. TRIAL REGISTRATION: ClinicalTrials.gov ID: NCT01938963 ; First posted: September 10, 2013.

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8154

PROTOCOL: Opioid‐specific medication‐assisted therapy and its impact on criminal justice and overdose outcomes

Type: Journal Article

Authors: C. C. Strange, Sarah M. Manchak, Jordan M. Hyatt, Cory Haberman, Alisha Desai

Year: 2021

Publication Place: Oslo

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8155

Provider and patient perspectives on barriers to buprenorphine adherence and the acceptability of video directly observed therapy to enhance adherence

Type: Journal Article

Authors: Margo E. Godersky, Andrew J. Saxon, Joseph O. Merrill, Jeffrey H. Samet, Jane M. Simoni, Judith I. Tsui

Year: 2019

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8156

Provider and Patient-panel Characteristics Associated With Initial Adoption and Sustained Prescribing of Medication for Opioid Use Disorder

Type: Journal Article

Authors: G. Cochran, E. S. Cole, M. Sharbaugh, D. Nagy, A. J. Gordon, W. F. Gellad, J. Pringle, T. Bear, J. Warwick, C. Drake, C. H. Chang, E. DiDomenico, D. Kelley, J. Donohue

Year: 2021

Publication Place: United States

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8157

Provider and Patient-panel Characteristics Associated With Initial Adoption and Sustained Prescribing of Medication for Opioid Use Disorder

Type: Journal Article

Authors: G. Cochran, E. S. Cole, M. Sharbaugh, D. Nagy, A. J. Gordon, W. F. Gellad, J. Pringle, T. Bear, J. Warwick, C. Drake, C. H. Chang, E. DiDomenico, D. Kelley, J. Donohue

Year: 2022

Publication Place: United States

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8158

Provider and Staff Perceptions and Experiences Implementing Behavioral Health Integration in Six Low-Income Health Care Organizations

Type: Journal Article

Authors: Heather Farb, Katie Sacca, Margaret Variano, Lisa Gentry, Meagan Relle, Jane Bertrand

Year: 2018

Publication Place: United States

Abstract:

Behavioral health integration (BHI) is a proven, effective practice for addressing the joint behavioral health and medical health needs of vulnerable populations. As part of the New Orleans Charitable Health Fund (NOCHF) program, this study addressed a gap in literature to better understand factors that impact the implementation of BHI by analyzing perceptions and practices among staff at integrating organizations. Using a mixed-method design, quantitative results from the Levels of Integration Measure (LIM), a survey tool for assessing staff perceptions of BHI in primary care settings (n=86), were analyzed alongside qualitative results from in-depth interviews with staff (n=27). Findings highlighted the roles of strong leadership, training, and process changes on staff collaboration, relationships, and commitment to BHI. This study demonstrates the usefulness of the LIM in conjunction with in-depth interviews as an assessment tool for understanding perceptions and organizational readiness for BHI implementation.

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8159

Provider based interventions to mitigate risk for opioid pain medication abuse among adult patients in a primary care setting

Type: Web Resource

Authors: Sheree Conley-Donaldson

Year: 2018

Topic(s):

, ,

Disclaimer:

This grey literature reference is included in the Academy's Literature Collection in keeping with our mission to gather all sources of information on integration. Grey literature is comprised of materials that are not made available through traditional publishing avenues. Often, the information from unpublished resources can be limited and the risk of bias cannot be determined.

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8160

Provider Directory Solutions: Market Assessment and Opportunities Analysis

Type: Government Report

Authors: G. Morris, S. Afzal, M. Bhasker, D. Finney

Year: 2012

Topic(s):

,

Disclaimer:

This grey literature reference is included in the Academy's Literature Collection in keeping with our mission to gather all sources of information on integration. Grey literature is comprised of materials that are not made available through traditional publishing avenues. Often, the information from unpublished resources can be limited and the risk of bias cannot be determined.

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