Substance Use Tools & Resources    

This brief describes research documenting the added challenges stimulant use contributes to those who use opioids and patient-centered approaches for working with people who use stimulants that are enrolled in medication treatment for opioid use disorder.

This brief reviews opioid and stimulant trends in availability, use, and impacts; compares opioids and stimulants in terms of drug effects and motivations for use; and examines the factors that drive co-use.

The Assistant Secretary for Planning and Evaluation (ASPE) convened an interagency workgroup of key U.S. Department of Health & Human Services (HHS) experts in overdose prevention and substance use disorders to develop a new strategy to address the evolving nature of the broadened overdose crisis.This issue brief discusses the Strategy in greater detail, including the objectives under each priority area, associated activities, and guiding principles.

This brief examines the prevalence of diagnoses of polysubstance use disorders, describes the characteristics of Medicaid enrollees with polysubstance use disorders, and compares the mental health and medical comorbidities based on the number of unique substance use disorders.

This NIDA web page includes facts and figures on prescription opioids.

These estimated costs of opioid use disorder and fatal opioid overdose and their per capita costs at the state level can assist federal and state decision makers in understanding the magnitude of opioid use disorder and fatal opioid overdose in their jurisdictions.

This chart includes workplace data from the U.S. Bureau of Labor Statistics on unintentional overdose deaths involving the nonmedical use of drugs or alcohol from 2011-2021.

This guide is a resource for health care systems to improve mental health and well-being in the communities they serve, focusing specifically on saving lives from deaths of despair. The guide endeavors to provide a comprehensive framework in which multiple stakeholders (e.g., people from marginalized populations and communities and leaders in sectors such as health care, education, justice system, local government, employers) can identify themselves and their contributions. A specific emphasis is placed on the role of health care systems in impacting the care they deliver and leveraging all of their assets to improve the health of populations and communities.