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Opioids & SU

The Literature Collection contains over 11,000 references for published and grey literature on the integration of behavioral health and primary care. Learn More

Use the Search feature below to find references for your terms across the entire Literature Collection, or limit your searches by Authors, Keywords, or Titles and by Year, Type, or Topic. View your search results as displayed, or use the options to: Show more references per page; Sort references by Title or Date; and Refine your search criteria. Expand an individual reference to View Details. Full-text access to the literature may be available through a link to PubMed, a DOI, or a URL. References may also be exported for use in bibliographic software (e.g., EndNote, RefWorks, Zotero).

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12581 Results
4781
Gather "Round": An Integrated Care Model for the Emergency Department Multi-Visit Patient
Type: Journal Article
Authors: A. Feld, M. Carollo, J. Freeman-Reyes, S. McCarthy, M. A. Lind, R. Weinstein, C. O'Dea, M. Joy, E. J. Morley, P. Aitken, R. Schwaner, D. Giarraputo, S. M. Heslin
Year: 2025
Abstract:

PURPOSE: Emergency departments (EDs) are a vital component of the United States healthcare system and care for over 130 million patient visits annually. Nonurgent ED visits can contribute to crowding, delays in care, and adverse effects. Many high-utilizing ED patients may present with complex medical, behavioral, and social needs that are not necessarily emergent or urgent in nature. The authors created an Integrated Care Model, called the Multi-Visit Patient (MVP) program, for patients with 5 or more visits to the ED in a rolling 12-month period. The MVP program incorporated an interdisciplinary group of ED leadership and case management (CM) to identify, engage, and intervene with ED MVPs, aiming to improve their ED utilization. Patients received comprehensive screenings for depression, falls, alcohol use disorder, caregiver support, social determinants of health, and more. Based on these screenings, the CM team implemented interventions such as connecting patients with outpatient specialists and linking patients to community-based organizations to optimize stability, wellness, and reduce ED utilization. PRIMARY PRACTICE SETTING: The collaboratively developed MVP program was implemented in the ED of a large, suburban, tertiary care academic hospital. FINDINGS/CONCLUSIONS: The MVP program identified 221 MVP patients over a 20-month period and successfully connected with 89% of them. Of these 221 patients, 78% (172 patients) chose to engage in the MVP program, with 160 completing their engagement with an outcome. Among the patients who completed their engagement and for whom the study could match separate utilization data (151 patients), the study observed a 57% reduction in ED visits. IMPLICATIONS FOR CASE MANAGEMENT PRACTICE: Case managers play a crucial role in the effectiveness of the MVP program by coordinating comprehensive care for high-utilizing ED patients. The MVP program includes transition of care initiatives designed to improve patient outcomes. Through screenings and targeted interventions, case managers identify and address the complex medical, behavioral, and social needs of MVP patients. This collaborative, interdisciplinary approach underscores the importance of timely and coordinated care, benefiting both patients and the health system. The MVP program exemplifies the critical role of case managers in reducing unnecessary ED visits and enhancing overall patient care.

Topic(s):
Measures See topic collection
4782
Gender and age effects on the trajectory of depression in opioid users during methadone maintenance treatment
Type: Journal Article
Authors: Peng-Wei Wang, Huang-Chi Lin, Yi-Hsin Connie Yang, Chih-Yao Hsu, Kuan-Sheng Chung, Hung-Chi Wu, Cheng-Fang Yen
Year: 2017
Topic(s):
Healthcare Disparities See topic collection
,
Opioids & Substance Use See topic collection
4783
Gender and symptoms in primary care practices
Type: Journal Article
Authors: J. L. Jackson, J. Chamberlin, K. Kroenke
Year: 2003
Publication Place: United States
Abstract: The authors sought to explore gender differences among patients with physical symptoms who came to see internists. The women were younger, more likely to report stress, endorsed more "other, currently bothersome" symptoms, were more likely to have a mental disorder, and were less likely to be satisfied with their care. The men were slower to improve, but there was no difference between the sexes after 3 months. There were no differences in the number, type, duration, or severity of symptoms or in the expectation of care, costs of visits, intervention received, use of health care services, or likelihood of being considered difficult by their physician. The gender of the clinician had no effect on any outcome.
Topic(s):
Healthcare Disparities See topic collection
,
Medically Unexplained Symptoms See topic collection
4784
Gender Differences among Prisoners with Pre-Incarceration Heroin Dependence Participating in a Randomized Clinical Trial of Buprenorphine Treatment
Type: Journal Article
Authors: Michael S. Gordon, Timothy W. Kinlock, Kathryn A. Couvillion, Monique E. Wilson, Robert P. Schwartz, Kevin E. O'Grady
Year: 2013
Topic(s):
Opioids & Substance Use See topic collection
,
Healthcare Disparities See topic collection
4785
Gender differences in adolescents attending a drug and alcohol withdrawal service
Type: Journal Article
Authors: A. J. Dean, M. McBride, E. M. Macdonald, Y. Connolly, B. M. McDermott
Year: 2010
Publication Place: England
Abstract: INTRODUCTION AND AIMS: Gender differences have been reported in adult substance users, but little research has examined gender differences in adolescents presenting to treatment services. This study aimed to explore gender differences in adolescents presenting to a withdrawal service. DESIGN AND METHODS: All presentations to a withdrawal service between March 2000 and September 2004 were identified. For each presentation, the following information was extracted from clinical databases: sociodemographics, drug use, risk-taking behaviour, mental health symptoms, reasons and context of drug use. Significant gender differences identified at bivariate analysis were then incorporated into multivariate models exploring predictors of heroin use, cannabis use and sharing injecting equipment. RESULTS: A total of 262 young people were admitted during the study period (53% male, mean age 16.8 years; SD 1.13). Bivariate analysis indicated that girls were more likely to report: being homeless, using a greater number of substances, using heroin and amphetamines, higher rates of injecting, sharing injecting equipment and using with a partner. Multivariate analysis identified that being female was an independent predictor of heroin use and that being male was an independent predictor of cannabis use. Significant predictors of sharing injecting equipment were using with a partner and current use of heroin; the effect of gender was not significant after controlling for other factors. DISCUSSION AND CONCLUSIONS: Our findings indicate that male and female adolescents presenting to a withdrawal treatment service exhibit differences in substance use characteristics. Future research should examine the role of gender in determining optimal treatment approaches in substance-using adolescents.
Topic(s):
Opioids & Substance Use See topic collection
,
Healthcare Disparities See topic collection
4787
Gender differences in drug use among individuals under arrest
Type: Journal Article
Authors: Bridget E. Weller, Stephen Magura, Dawn R. Smith, Matthew M. Saxton, Piyadarsha Amaratunga
Year: 2022
Topic(s):
Healthcare Disparities See topic collection
,
Opioids & Substance Use See topic collection
4788
Gender differences in health-related quality of life on admission to a maintenance treatment program
Type: Journal Article
Authors: S. M. Giacomuzzi, Y. Riemer, M. Ertl, G. Kemmler, H. Rossler, H. Hinterhuber, M. Kurz
Year: 2005
Publication Place: Switzerland
Topic(s):
Opioids & Substance Use See topic collection
4789
Gender differences in mortality among treated opioid dependent patients
Type: Journal Article
Authors: E. Evans, A. Kelleghan, L. Li, J. Min, D. Huang, D. Urada, Y. I. Hser, B. Nosyk
Year: 2015
Publication Place: Ireland
Abstract: AIMS: To assess gender differences in characteristics, mortality rates, and the causes and predictors of death among treated opioid-dependent individuals. METHODS: Linked vital statistics data were obtained for all individuals first enrolled in publicly funded pharmacological treatment for opioid dependence in California from 2006 to 2010. Standardized mortality ratios (SMR) were calculated by gender. Cox proportional hazards models with time-varying covariates were fitted to determine the effect of gender on the hazard of all-cause mortality, controlling for covariates. RESULTS: Over a median 2.6 years (interquartile range: 1.4-3.7), 1.031 deaths were observed, including 2.2% (259/11,564) of women and 3.7% (772/20,758) of men. Women had a greater increased risk of mortality compared to the general population (SMR 5.1 95% CI: 4.5, 5.7) than men (SMR 4.3 95% CI: 4.0, 4.6). The relative risk of death for women compared with men was 1.18 (95% CI: 1.02, 1.36). Women had a lower instantaneous hazard of all-cause mortality than men (HR 0.58, 95% CI 0.50, 0.68), controlling for other factors. Significant interaction effects indicated that among men, mortality risk was decreased by full-time employment and increased by non-daily heroin use (relative to daily use) and medical problems. Concurrent opioid and methamphetamine/cocaine use increased mortality risk among women and decreased it among men. CONCLUSIONS: Treatment for opioid dependence is likely to reduce mortality risk among men by addressing employment and medical problems, and via interventions to reduce overdose risk after heroin abstinence, and among women by attending to the concurrent use of methamphetamine/cocaine and opioids.
Topic(s):
Opioids & Substance Use See topic collection
4790
Gender Differences in Prevalence of Somatoform Disorders in Patients Visiting Primary Care Centers: Original Research
Type: Journal Article
Authors: Abdulbari Bener
Year: 2010
Publication Place: United States
Topic(s):
Healthcare Disparities See topic collection
,
Medically Unexplained Symptoms See topic collection
4791
Gender differences in receipt of telehealth versus in person behavioral therapy, medication for opioid use disorder (MOUD), and 90-day MOUD retention during the pandemic: A retrospective veteran cohort study
Type: Journal Article
Authors: N. A. Livingston, A. Sarpong, R. Sistad, C. Roth, A. N. Banducci, T. Simpson, J. Hyde, M. Davenport, R. Weisberg
Year: 2024
Abstract:

BACKGROUND: COVID-19 significantly negatively impacted access to care among patients with opioid use disorder (OUD). The Veterans Health Administration (VHA) enacted policies to expand telehealth and medication for OUD (MOUD) during the public health emergency, which offset risk of treatment disruption. In this study, we evaluated gender differences in utilization of behavioral therapy in person and via telehealth, MOUD utilization, and achieving 90-day MOUD retention pre-post pandemic onset, given known gender differences in treatment utilization between men and women. Secondarily, we examined MOUD receipt and retention as a function of in-person vs. telehealth behavioral therapy received over time. METHODS: Using VHA's nationwide electronic health record data, we compared outcomes between men and women veterans, pre- to post-pandemic onset (January 2019-February 2020 vs. March 2020-April 2021). Primary outcomes included receipt of behavioral therapy (in person or telehealth), number of appointments attended, any MOUD, and whether patients achieved 90-day MOUD retention post-induction. RESULTS: Veterans with OUD were less likely to receive behavioral therapy post-pandemic onset, which was driven by marked decreases in in-person care; these effects were strongest among women. The odds of receiving MOUD also decreased pre- to post-pandemic onset, particularly among men. Receipt of or achieving 90-day MOUD retention was differentially related to receipt of behavioral therapy via in person vs. telehealth; telehealth was more strongly associated with these utilization indicators post-pandemic onset-an effect that was more pronounced for men. CONCLUSION: The likelihood of receiving behavioral therapy and MOUD were lower during COVID-19 and varied by gender, with men being less likely to receive MOUD over time and women being less likely to receive in-person behavioral therapy. Behavioral therapy received via telehealth was generally associated with improved MOUD utilization compared to in-person behavioral therapy, but this was less true for women than for men regarding utilization of or achieving 90-day MOUD retention. In addition to the need for further telehealth expansion for veterans with OUD, more research should explore how to better engage men in MOUD treatment and improve adherence to MOUD among women engaged in behavioral therapy.

Topic(s):
Opioids & Substance Use See topic collection
,
Healthcare Disparities See topic collection
,
HIT & Telehealth See topic collection
4792
Gender differences in the stress-buffering effects of mindfulness facets on substance use among low-income adolescents
Type: Journal Article
Authors: E. C. Helminen, T. L. Ash, E. L. Cary, S. E. Sinegar, P. Janack, R. DiFlorio, J. C. Felver
Year: 2023
Topic(s):
Opioids & Substance Use See topic collection
,
Healthcare Disparities See topic collection
4793
Gender differences in treatment and clinical characteristics among patients receiving extended release naltrexone
Type: Journal Article
Authors: D. M. Herbeck, K. E. Jeter, S. J. Cousins, R. Abdelmaksoud, D. Crevecoeur-MacPhail
Year: 2016
Abstract: Further research is needed to investigate real-world acceptability of extended-release naltrexone for alcohol and opioid use disorders, and potential gender differences. This study examines treatment and clinical characteristics among men and women receiving extended-release naltrexone in a large, publicly funded substance use disorder treatment system (N = 465; 52% female). Patient demographics, treatment characteristics, and the number of extended-release naltrexone doses received were collected from administrative data and treatment program staff. Additionally, patients provided information on experiences with extended-release naltrexone in an open-ended format at 1, 2, and 3 weeks following their first injection. For a subsample of patients (N = 220), alcohol/opioid cravings and specific adverse effects were also assessed. Compared to men, women reported experiencing a higher rate and mean number of adverse effects. Overall, craving scores showed substantial reductions over time. However, among patients taking extended-release naltrexone for alcohol use, women showed a significantly greater reduction in craving scores compared to men. No gender differences were observed in the number of extended-release naltrexone doses received. Although women may have a greater need for additional support in managing early adverse effects, extended-release naltrexone as an adjunct to psychosocial treatment may be an acceptable and promising treatment approach for both men and women, and particularly for women prescribed extended-release naltrexone for alcohol use. This study contributes further information on patients' experiences during the early course of extended-release naltrexone treatment in real-world settings. Understanding these experiences may assist policy makers and treatment providers in addressing challenges of implementing this treatment into wider practice.
Topic(s):
Opioids & Substance Use See topic collection
4794
Gender differences of mental health consumers accessing integrated primary and behavioral care
Type: Journal Article
Authors: H. Gleason, M. Hobart, L. Bradley, J. Landers, S. Langenfeld, M. Tonelli, M. Kolodziej
Year: 2014
Abstract: Persons with severe mental illness and addiction are at higher risk for early morbidity and mortality than the general population, and are less likely to receive primary care and preventive health services. Primary and behavioral integrated care programs aim to reduce these health disparities by providing comprehensive health and wellness services. Gender in particular may play a significant role in individuals' engagement and outcomes in such programs. Hence, this study examines the salient characteristics of behavioral health consumers accessing an integrated care program at a large community mental health center. Baseline gender differences in consumer demographics, substance use, psychological distress and functioning, physical health indicators, and risk factors for serious medical conditions are examined. Our results demonstrate that key gender differences exist and may warrant distinct treatment needs for men and women receiving integrated care.
Topic(s):
Healthcare Disparities See topic collection
4795
Gender disparities in physician-patient communication among African American patients in primary care
Type: Journal Article
Authors: Robin Dimatteo, Carolyn B. Murray, Summer L. Williams
Year: 2009
Publication Place: United States
Topic(s):
Education & Workforce See topic collection
,
Healthcare Disparities See topic collection
4796
Gender disparities in the treatment of late-life depression: qualitative and quantitative findings from the IMPACT trial
Type: Journal Article
Authors: L. Hinton, M. Zweifach, S. Oishi, L. Tang, J. Unutzer
Year: 2006
Topic(s):
Healthcare Disparities See topic collection
4797
Gender Issues in the Pharmacotherapy of Opioid-Addicted Women: Buprenorphine
Type: Journal Article
Authors: Annemarie Unger, Erika Jung, Bernadette Winklbaur, Gabriele Fischer
Year: 2010
Topic(s):
Opioids & Substance Use See topic collection
,
Healthcare Disparities See topic collection
4798
Gender-related self-reported mental health inequalities in primary care in England: a cross-sectional analysis using the GP Patient Survey
Type: Journal Article
Authors: R. E. Watkinson, A. Linfield, J. Tielemans, I. Francetic, L. Munford
Year: 2024
Topic(s):
Healthcare Disparities See topic collection
,
Measures See topic collection
4799
Gender-specific predictors of methadone treatment outcomes among African Americans at an urban clinic
Type: Journal Article
Authors: J. J. Lister, S. Brown, M. K. Greenwald, D. M. Ledgerwood
Year: 2019
Publication Place: United States
Abstract: Background: African American patients with opioid use disorder (OUD) have demonstrated poorer methadone maintenance treatment (MMT) outcomes compared with white patients. This issue is further complicated in urban settings, where African Americans experience high rates of poverty and publicly funded treatment. Despite interrelated factors that disadvantage African Americans, the literature focusing on this population is scant. To address this shortcoming, we conducted the first investigation of gender differences and gender-specific MMT outcome predictors among African Americans (or any racial minority population). This study provides gender-specific findings to improve African American MMT outcomes. Methods: We studied 211 African American patients (male: n = 137, 64.9%) at an urban, university-affiliated MMT clinic. We used existing intake data to assess baseline demographic, substance use, mental health, and interpersonal factors. Primary outcomes were 3-month drug(+) (positive) urine drug screen (UDS) results and treatment retention. Results: Women were more likely (than men) to endorse histories of interpersonal violence, substance abuse in their social network, and mental health problems. Men reported a greater likelihood (than women) for early opioid-use onset and a lack of prior MMT. There were no gender differences in 3-month drug(+) UDS or treatment retention. In multivariable analyses among women, no baseline factors predicted 3-month opioid(+) UDS and physical abuse history predicted a higher proportion of 3-month cocaine(+) UDS. Among men, primary injection opioid use and older age best predicted a higher proportion of 3-month cocaine(+) UDS and parent substance abuse predicted shorter retention. In both gender-stratified analyses, higher proportions of 3-month opioid(+) UDS and cocaine(+) UDS predicted shorter retention. Conclusions: This study offers an analysis of gender differences in risk factors, MMT outcomes, and gender-specific predictors among African American patients. MMT clinics should tailor assessment and treatment protocols to address gender-specific needs.
Topic(s):
Opioids & Substance Use See topic collection
,
Healthcare Disparities See topic collection
4800
General medical and pharmacy claims expenditures in users of behavioral health services
Type: Journal Article
Authors: Roger G. Kathol, Donna McAlpine, Yasuhiro Kishi, Robert Spies, William Meller, Terence Bernhardt, Steven Eisenberg, Keith Folkert, William Gold
Year: 2005
Topic(s):
Financing & Sustainability See topic collection