Literature Collection

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Opioids & SU

The Literature Collection contains over 11,000 references for published and grey literature on the integration of behavioral health and primary care. Learn More

Use the Search feature below to find references for your terms across the entire Literature Collection, or limit your searches by Authors, Keywords, or Titles and by Year, Type, or Topic. View your search results as displayed, or use the options to: Show more references per page; Sort references by Title or Date; and Refine your search criteria. Expand an individual reference to View Details. Full-text access to the literature may be available through a link to PubMed, a DOI, or a URL. References may also be exported for use in bibliographic software (e.g., EndNote, RefWorks, Zotero).

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11193 Results
6521
Naloxone for Opioid Overdose: Comment
Type: Journal Article
Authors: G. G. Pattullo
Year: 2024
Topic(s):
Opioids & Substance Use See topic collection
Reference Links:       
6522
Naloxone for Opioid Overdose: Life-Saving Science
Type: Government Report
Authors: National Institute on Drug Abuse
Year: 2017
Topic(s):
Grey Literature See topic collection
,
Opioids & Substance Use See topic collection
Disclaimer:

This grey literature reference is included in the Academy's Literature Collection in keeping with our mission to gather all sources of information on integration. Grey literature is comprised of materials that are not made available through traditional publishing avenues. Often, the information from unpublished resources can be limited and the risk of bias cannot be determined.

6523
Naloxone for Opioid Overdose: Reply
Type: Journal Article
Authors: M. van Lemmen, J. Florian, Z. Li, M. van Velzen, E. van Dorp, M. Niesters, E. Sarton, E. Olofsen, R. van der Schrier, D. G. Strauss, A. Dahan
Year: 2024
Topic(s):
Opioids & Substance Use See topic collection
Reference Links:       
6525
Naloxone Prescribing and Education in Outpatient Pain Management and Palliative Care
Type: Journal Article
Authors: L. M. Coons, Gardea Hart, A. White, S. Summers
Year: 2021
Publication Place: England
Abstract:

Over the past two decades, opioid use and overdose have increased substantially. Naloxone, an opioid overdose reversal agent, has been one of many risk mitigation strategies for preventing mortality due to overdose. Most literature describing naloxone utilization has been about populations of illicit drug users and patients in hospitals, primary care, and pharmacies. There is limited information regarding naloxone prescribing and training for opioid users in specialty pain management clinics. Furthermore, there are no known publications concerning patients receiving palliative care services and overdose prevention. Pain and palliative care patients are commonly at risk of opioid overdose. In an interdisciplinary outpatient pain and palliative care clinic, pharmacists implemented naloxone prescribing and education. Eleven patients at increased risk for overdose were prescribed naloxone and educated on overdose risk factors, recognition, and management. Seven patients reported picking up their naloxone prescription from the pharmacy, and none reported using it within two weeks of the initial education. This intervention was deemed successful within the clinic, but small sample size and the pharmacist role may not be replicable within other pain and palliative care settings. It encourages further research of overdose risk and prevention in pain management and palliative care.

Topic(s):
Education & Workforce See topic collection
,
Healthcare Disparities See topic collection
,
Opioids & Substance Use See topic collection
6526
Naloxone prescribing to older adults in primary care
Type: Journal Article
Authors: Caroline D. Luther, Tamera D. Hughes, Stefanie P. Ferreri
Year: 2021
Topic(s):
Education & Workforce See topic collection
,
Healthcare Disparities See topic collection
,
Opioids & Substance Use See topic collection
6527
Naloxone Telephone Outreach Program in an outpatient mental health clinic: A quality improvement project
Type: Journal Article
Authors: Jrywan N. Huang, Margit Gerardi, Olivia Yeargain, Tracy Senterfitt, Maria Saldiva
Year: 2023
Topic(s):
Healthcare Disparities See topic collection
6528
Naloxone use among overdose prevention trainees in New York City: A longitudinal cohort study
Type: Journal Article
Authors: A. Siegler, Z. Huxley-Reicher, L. Maldjian, R. Jordan, C. Oliver, A. Jakubowski, H. V. Kunins
Year: 2017
Publication Place: Ireland
Topic(s):
Opioids & Substance Use See topic collection
6530
Naloxone: The Opioid Reversal Drug that Saves Lives
Type: Web Resource
Authors: U.S. Department of Health and Human Services
Year: 2018
Topic(s):
Grey Literature See topic collection
,
Opioids & Substance Use See topic collection
Disclaimer:

This grey literature reference is included in the Academy's Literature Collection in keeping with our mission to gather all sources of information on integration. Grey literature is comprised of materials that are not made available through traditional publishing avenues. Often, the information from unpublished resources can be limited and the risk of bias cannot be determined.

6532
Naltrexone (50 mg) Plus Psychotherapy in Alcohol-Dependent Patients: A Meta-Analysis of Randomized Controlled Trials
Type: Journal Article
Authors: Joanna Jarosz, Katarzyna Miernik, Maria Wachal, Jacek Walczak, Gunther Krumpl
Year: 2013
Topic(s):
Opioids & Substance Use See topic collection
6533
Naltrexone alters responses to social and physical warmth: Implications for social bonding
Type: Journal Article
Authors: Tristen K. Inagaki, Laura I. Hazlett, Carmen Andreescu
Year: 2019
Topic(s):
Opioids & Substance Use See topic collection
6534
Naltrexone at low doses upregulates a unique gene expression not seen with normal doses: Implications for its use in cancer therapy
Type: Journal Article
Authors: W. M. Liu, K. A. Scott, J. L. Dennis, E. Kaminska, A. J. Levett, A. G. Dalgleish
Year: 2016
Publication Place: Greece
Abstract: It has been reported that lower doses of the opioid antagonist naltrexone are able to reduce tumour growth by interfering with cell signalling as well as by modifying the immune system. We have evaluated the gene expression profile of a cancer cell line after treatment with low-dose naltrexone (LDN), and assessed the effect that adapting treatment schedules with LDN may have on enhancing efficacy. LDN had a selective impact on genes involved with cell cycle regulation and immune modulation. Similarly, the pro-apoptotic genes BAD and BIK1 were increased only after LDN. Continuous treatment with LDN had little effect on growth in different cell lines; however, altering the treatment schedule to include a phase of culture in the absence of drug following an initial round of LDN treatment, resulted in enhanced cell killing. Furthermore, cells pre-treated with LDN were more sensitive to the cytotoxic effects of a number of common chemotherapy agents. For example, priming HCT116 with LDN before treatment with oxaliplatin significantly increased cell killing to 49+/-7.0 vs. 14+/-2.4% in cultures where priming was not used. Interestingly, priming with NTX before oxaliplatin resulted in just 32+/-1.8% cell killing. Our data support further the idea that LDN possesses anticancer activity, which can be improved by modifying the treatment schedule.
Topic(s):
Opioids & Substance Use See topic collection
6535
Naltrexone Compared With Buprenorphine or Methadone in Pregnancy: A Systematic Review
Type: Journal Article
Authors: S. Atluru, A. K. Bruehlman, P. Vaughn, C. W. Schauberger, M. C. Smid
Year: 2024
Topic(s):
Opioids & Substance Use See topic collection
,
Healthcare Disparities See topic collection
6536
Naltrexone differentially modulates the neural correlates of motor impulse control in abstinent alcohol-dependent and polysubstance-dependent individuals
Type: Journal Article
Authors: L. J. Nestor, L. M. Paterson, A. Murphy, J. McGonigle, C. Orban, L. Reed, E. Taylor, R. Flechais, D. Smith, E. T. Bullmore, K. D. Ersche, J. Suckling, R. Elliott, B. Deakin, I. Rabiner, Lingford Hughes, B. J. Sahakian, T. W. Robbins, D. J. Nutt, ICCAM Consortium
Year: 2019
Topic(s):
Opioids & Substance Use See topic collection
,
Healthcare Disparities See topic collection
6537
Naltrexone for adolescent opioid use disorder: A bridge in the treatment gap?
Type: Journal Article
Authors: Matthew LaCasse, Joanna Quigley
Year: 2022
Topic(s):
Healthcare Disparities See topic collection
6539
Naltrexone Treatment for Opioid Use Disorder: Training for Clinicians (Part 1)
Type: Web Resource
Authors: Adam Bisaga
Year: 2017
Topic(s):
Grey Literature See topic collection
,
Education & Workforce See topic collection
,
Opioids & Substance Use See topic collection
Disclaimer:

This grey literature reference is included in the Academy's Literature Collection in keeping with our mission to gather all sources of information on integration. Grey literature is comprised of materials that are not made available through traditional publishing avenues. Often, the information from unpublished resources can be limited and the risk of bias cannot be determined.

6540
Naltrexone: A Pan-Addiction Treatment?
Type: Journal Article
Authors: E. Aboujaoude, W. O. Salame
Year: 2016
Abstract: Addiction is a major public health problem with few efficacious and safe treatments. The goal of this review is to provide an evidence-based assessment of the therapeutic role of the opioid antagonist naltrexone across the addiction spectrum-substance-based and behavioral. The PubMed database was searched for randomized, placebo-controlled clinical trials that investigated the oral or intramuscular long-acting formulation of naltrexone in substance use disorders or behavioral addictions such as pathological gambling, kleptomania, and trichotillomania. Thirty-nine efficacy studies were retrieved, covering alcohol use disorder (n = 22), opioid use disorder (n = 6), nicotine use disorder (n = 5), stimulant use disorder (n = 2), gambling disorder (n = 2), trichotillomania (n = 1), and kleptomania (n = 1). Despite the very different presentations within and between both addiction categories, the data, as a whole, show consistency in favor of naltrexone's relative efficacy and safety. Given the potential benefit and good tolerability revealed in the studies, the high morbidity associated with addiction, and the dearth of alternate treatments, naltrexone would seem like an underutilized treatment option. Further, naltrexone's seemingly broad anti-addiction efficacy supports a shared role for brain opioid pathways in the pathophysiology of addiction, broadly defined. More studies investigating the efficacy and tolerability of naltrexone and other opioid modulators are warranted. Studies should also further examine the effect of combining psychotherapy with naltrexone, as well as the potential role of naltrexone in treating comorbid addictions.
Topic(s):
Opioids & Substance Use See topic collection