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Opioids & SU

The Literature Collection contains over 11,000 references for published and grey literature on the integration of behavioral health and primary care. Learn More

Use the Search feature below to find references for your terms across the entire Literature Collection, or limit your searches by Authors, Keywords, or Titles and by Year, Type, or Topic. View your search results as displayed, or use the options to: Show more references per page; Sort references by Title or Date; and Refine your search criteria. Expand an individual reference to View Details. Full-text access to the literature may be available through a link to PubMed, a DOI, or a URL. References may also be exported for use in bibliographic software (e.g., EndNote, RefWorks, Zotero).

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12780 Results
4001
Efficient and effective measurement of provider competence in community-based substance use treatment settings: Performance of the Motivational Interviewing Coach Rating Scale (MI-CRS)
Type: Journal Article
Authors: S. Naar, J. E. Chapman, G. A. Aarons
Year: 2023
Topic(s):
Opioids & Substance Use See topic collection
,
Measures See topic collection
4002
Efficient, but separate behavioral, physical healthcare is 'a delusion'
Type: Web Resource
Authors: D. Grantham
Year: 2013
Topic(s):
Financing & Sustainability See topic collection
,
Grey Literature See topic collection
Disclaimer:

This grey literature reference is included in the Academy's Literature Collection in keeping with our mission to gather all sources of information on integration. Grey literature is comprised of materials that are not made available through traditional publishing avenues. Often, the information from unpublished resources can be limited and the risk of bias cannot be determined.

4003
eHealth Familias Unidas Mental Health: Protocol for an effectiveness-implementation hybrid Type 1 trial to scale a mental health preventive intervention for Hispanic youth in primary care settings
Type: Journal Article
Authors: Yannine Estrada, Alyssa Lozano, Devina Boga, Maria I. Tapia, Tatiana Perrino, Maria Rosa Velazquez, Lourdes Forster, Nicole Torres, Cecilia V. Morales, Lisa Gwynn, William R. Beardslee, Hendricks Brown, Guillermo Prado
Year: 2023
Topic(s):
Healthcare Disparities See topic collection
,
Opioids & Substance Use See topic collection
4004
Eight principles for safer opioid prescribing and cautions with benzodiazepines
Type: Journal Article
Authors: L. R. Webster, G. M. Reisfield, N. Dasgupta
Year: 2015
Publication Place: England
Abstract: The provision of long-term opioid analgesic therapy for chronic pain requires a careful risk/benefit analysis followed by clinical safety measures to identify and reduce misuse, abuse, and addiction and their associated morbidity and mortality. Multiple data sources show that benzodiazepines, prescribed for comorbid insomnia, anxiety, and mood disorders, heighten the risk of respiratory depression and other adverse outcomes when combined with opioid therapy. Evidence is presented for hazards associated with coadministration of opioids and benzodiazepines and the need for caution when initiating opioid therapy for chronic pain. Clinical recommendations follow, as drawn from 2 previously published literature reviews, one of which proffers 8 principles for safer opioid prescribing; the other review presents risks associated with benzodiazepines, suggests alternatives for co-prescribing benzodiazepines and opioids, and outlines recommendations regarding co-prescribing if alternative therapies are ineffective.
Topic(s):
Opioids & Substance Use See topic collection
,
Education & Workforce See topic collection
4005
Eight ways to overcome resistance to medication-assisted treatment
Type: Report
Authors: Maureen Fitzgerald
Year: 2016
Topic(s):
Grey Literature See topic collection
,
Opioids & Substance Use See topic collection
Disclaimer:

This grey literature reference is included in the Academy's Literature Collection in keeping with our mission to gather all sources of information on integration. Grey literature is comprised of materials that are not made available through traditional publishing avenues. Often, the information from unpublished resources can be limited and the risk of bias cannot be determined.

4006
El Dorado Community Health Centers: Addressing the Opioid Epidemic in Rural California through Community Partnerships
Type: Government Report
Authors: Ashley Jasko, Meryl Schulman
Year: 2024
Publication Place: Hamilton, NJ
Topic(s):
Grey Literature See topic collection
,
Opioids & Substance Use See topic collection
,
Education & Workforce See topic collection
Disclaimer:

This grey literature reference is included in the Academy's Literature Collection in keeping with our mission to gather all sources of information on integration. Grey literature is comprised of materials that are not made available through traditional publishing avenues. Often, the information from unpublished resources can be limited and the risk of bias cannot be determined.

4007
Electronic adolescent substance use screening: Focus on implementation is needed
Type: Journal Article
Authors: Amy M. Yule, Alyssa Levin-Scherz, Julianna Brody-Fialkin, Dana S. Rubin, Caroline J. Kistin
Year: 2025
Topic(s):
HIT & Telehealth See topic collection
,
Healthcare Disparities See topic collection
4008
Electronic harm reduction interventions for drug overdose monitoring and prevention: A scoping review
Type: Journal Article
Authors: A. Loverock, T. Marshall, D. Viste, F. Safi, W. Rioux, N. Sedaghat, M. Kennedy, S. M. Ghosh
Year: 2023
Topic(s):
Opioids & Substance Use See topic collection
,
HIT & Telehealth See topic collection
4009
Electronic health record functionality needed to better support primary care
Type: Journal Article
Authors: A. H. Krist, J. W. Beasley, J. C. Crosson, D. C. Kibbe, M. S. Klinkman, C. U. Lehmann, C. H. Fox, J. M. Mitchell, J. W. Mold, W. D. Pace, K. A. Peterson, R. L. Phillips, R. Post, J. Puro, M. Raddock, R. Simkus, S. E. Waldren
Year: 2014
Abstract: Electronic health records (EHRs) must support primary care clinicians and patients, yet many clinicians remain dissatisfied with their system. This article presents a consensus statement about gaps in current EHR functionality and needed enhancements to support primary care. The Institute of Medicine primary care attributes were used to define needs and meaningful use (MU) objectives to define EHR functionality. Current objectives remain focused on disease rather than the whole person, ignoring factors such as personal risks, behaviors, family structure, and occupational and environmental influences. Primary care needs EHRs to move beyond documentation to interpreting and tracking information over time, as well as patient-partnering activities, support for team-based care, population-management tools that deliver care, and reduced documentation burden. While stage 3 MU's focus on outcomes is laudable, enhanced functionality is still needed, including EHR modifications, expanded use of patient portals, seamless integration with external applications, and advancement of national infrastructure and policies.
Topic(s):
HIT & Telehealth See topic collection
4010
Electronic Health Record Impact on Work Burden in Small, Unaffiliated, Community-Based Primary Care Practices
Type: Journal Article
Authors: Jenna Howard, Elizabeth C. Clark, Asia Friedman, Jesse C. Crosson, Maria Pellerano, Benjamin F. Crabtree, Ben-Tzion Karsh, Carlos R. Jaen, Douglas S. Bell, Deborah J. Cohen
Year: 2012
Topic(s):
HIT & Telehealth See topic collection
4011
Electronic health record-based monitoring of primary care patients at risk of medication-related toxicity
Type: Journal Article
Authors: D. G. Bundy, J. A. Marsteller, A. W. Wu, L. D. Engineer, S. M. Berenholtz, A. H. Caughey, D. Silver, J. Tian, R. E. Thompson, M. R. Miller, C. U. Lehmann
Year: 2012
Publication Place: United States
Abstract: BACKGROUND: Timely laboratory monitoring may reduce the potential harm associated with chronic medication use. A study was conducted to determine the proportion of patients receiving National Committee for Quality Assurance (NCQA)-recommended laboratory medication monitoring in a primary care setting and to assess the effect of electronic health record (EHR)-derived, paper-based, provider-specific feedback bulletins on subsequent patient receipt of medication monitoring. METHODS: In a single-arm, pre-post intervention in two federally qualified community health centers in Baltimore, patients targeted were adults prescribed at least 6 months (in the preceding year) for at least one index medication (digoxin, statins, diuretics, angiotensin-converting enzyme inhibitors/ angiotensin II-receptor blockers) in a 12-month period (August 2008-July 2009). RESULTS: Among the 2,013 patients for whom medication monitoring was recommended, 42% were overdue for monitoring at some point during the study. As the number of index medications the patient was prescribed increased, the likelihood of ever being overdue for monitoring decreased. Being listed on the provider-specific monitoring bulletin doubled the odds of a patient receiving recommended laboratory monitoring before the next measurement period (1-2 months). Limiting the intervention to the most overdue patients, however, mitigated its overall impact. CONCLUSIONS: Recommended laboratory monitoring of chronic medications appears to be inconsistent in primary care, resulting in potential harm for individuals at risk for medication-related toxicity. EHRs may be an important component of systems designed to improve medication monitoring, but multimodal interventions will likely be needed to achieve high reliability.
Topic(s):
HIT & Telehealth See topic collection
4012
Electronic health records and support for primary care teamwork
Type: Journal Article
Authors: A. S. O'Malley, K. Draper, R. Gourevitch, D. A. Cross, S. H. Scholle
Year: 2015
Topic(s):
Education & Workforce See topic collection
,
HIT & Telehealth See topic collection
4014
Electronic screening for mental health in rural primary care: feasibility and user testing
Type: Journal Article
Authors: S. P. Farrell, L. M. Zerull, I. H. Mahone, S. Guerlain, D. Akan, E. Hauenstein, J. Schorling
Year: 2009
Publication Place: United States
Abstract: Despite attention to prevention and screening for depression and alcohol use, Healthy People 2010 objectives continue to include goals to increase the detection of depression and decrease the rates of alcohol abuse. These problems remain significant. The overall goal of this study was to develop a computer-based electronic screening (eScreening) tool and determine the feasibility of implementing computer-based eScreening technology for rural visitors to a primary care clinic. The study called specifically for an electronic touch screen with voice prompts. This tool, called the eScreening tool, screens for alcohol abuse and depression among rural patients in a primary care setting. The screening was offered to rural adults who are not in acute distress and not at end of life, regardless of their stated reason for seeking medical care. Phase 1 of the pilot was used to determine the perceptions of nurses, other providers, and consumers regarding the acceptability and perceived usefulness of an eScreening tool. Phase 2 involved user testing of the eScreening tool. The longer term goals of the research program are to work with rural nurses to improve patient outcomes and develop interventions and for educational, consultation, and/or direct clinical care.
Topic(s):
HIT & Telehealth See topic collection
4015
Electronic screening for mental health in rural primary care: implementation
Type: Journal Article
Authors: S. P. Farrell, I. H. Mahone, L. M. Zerull, S. Guerlain, D. Akan, E. Hauenstein, J. Schorling
Year: 2009
Publication Place: United States
Abstract: The goals of this study were to develop a computer-based electronic screening tool (eScreening) and determine the feasibility of implementing eScreening for rural users of primary care. This descriptive pilot adapted existing screening measures for depression and alcohol abuse to a portable computer-based format and examined the feasibility of its adoption and use. This was a three-step design using convenience samples for (1) a focus group with providers, (2) usability testing with selected rural patients using the computerized touch screen, and (3) implementing the touch screen platform with a small sample in primary care to determine feasibility. This paper reports on Phase III, which assessed consumer response to eScreening.
Topic(s):
Education & Workforce See topic collection
,
HIT & Telehealth See topic collection
4016
Electronic Visit Use and Resolution Rates for Adult Outpatient Conditions in an Integrated Care Setting
Type: Journal Article
Authors: T. A. Lieu, J. Huang, K. Tran, D. Nguyen, M. E. Reed
Year: 2025
Abstract:

IMPORTANCE: Asynchronous structured electronic visits (e-visits) in which online systems ask defined questions about prespecified conditions are an emerging modality for providing highly convenient outpatient care. Scant information exists on their use and outcomes. OBJECTIVES: To (1) compare the percentage of initial visits made via e-visits with telephone, video, or office appointments for 4 common outpatient conditions; (2) compare rates of related follow-up visits within 7 days among visit modalities; and (3) identify patient characteristics associated with e-visit and follow-up visit use. DESIGN, SETTING, AND PARTICIPANTS: Cross-sectional analysis of e-visits and telephone, video, and office visits made in Kaiser Permanente Northern California, where The Permanente Medical Group provides care for 4.6 million patients. The study population was defined based on initial outpatient visits (e-visits, telephone or video appointment visits, or physician's office visits) by persons aged 18 years and older between January 1 and December 31, 2024, for 4 prespecified conditions. Data from 2023 and 2025 were used to analyze selected baseline variables. MAIN OUTCOMES AND MEASURES: The numbers of e-visits and other types of visits for 4 diagnoses (urinary tract infection [UTI], seasonal allergies, acne, and international travel advice) in adults from January through December 2024 identified in electronic health record data and, secondarily, telephone advice calls identified for UTI alone. Initial visits were those without previous visits or medications for the condition in the prior 365 days. Analyses of the rates of follow-up visits used modified Poisson regression and adjusted for patient characteristics. To simplify interpretation, adjusted percentages of different types of visits and adjusted rates of follow-up visits were calculated via marginal standardization. RESULTS: In 73 560 initial visits (86% by females; 41% by participants aged 18-39 years), e-visits were used in 58% (27 268 of 47 264) of UTI, 24% (3718 of 15 646) of seasonal allergy, 24% (1532 of 6426) of acne, and 56% (2377 of 4224) of international travel visits. E-visit use was highest among patients aged 18 to 29 years or 30 to 39 years for most conditions. After e-visits, follow-up visits for the same diagnosis within 7 days were uncommon: for UTI, the adjusted rate was 2.48%; for seasonal allergy, 6.45%; for acne, 2.11%; and for international travel, 0.12%. Follow-up visit rates after e-visits were lower than after other visit modalities for UTI, higher for seasonal allergy, and similar for acne and travel. For UTI e-visits, the risk of follow-up visits was higher among patients aged older than 65 years (adjusted relative risk, 2.50; 95% CI, 1.60-3.92), Hispanic patients, Asian patients, or those who were Medicaid insured. For seasonal allergy and acne, the risk of follow-up visits did not vary with patient characteristics. CONCLUSIONS AND RELEVANCE: In this cross-sectional study, high percentages of patients selected asynchronous physician-managed e-visits for common outpatient conditions in a setting where other visit types were available. Both e-visits and other visit types attained high rates of resolution without follow-up within 7 days.

Topic(s):
HIT & Telehealth See topic collection
4017
Elements of Integrated Behavioral Health Associated with Primary Care Provider Confidence in Managing Depression at Community Health Centers
Type: Journal Article
Authors: Erin M. Staab, Wen Wan, Amanda Campbell, Stacey Gedeon, Cynthia Schaefer, Michael T. Quinn, Neda Laiteerapong
Year: 2022
Topic(s):
Education & Workforce See topic collection
,
Healthcare Disparities See topic collection
4018
Elevated methylation and decreased serum concentrations of BDNF in patients in levomethadone compared to diamorphine maintenance treatment
Type: Journal Article
Authors: R. Schuster, A. Kleimann, M. K. Rehme, L. Taschner, A. Glahn, A. Groh, H. Frieling, R. Lichtinghagen, T. Hillemacher, S. Bleich, A. Heberlein
Year: 2017
Publication Place: Germany
Abstract: Brain-derived neurotrophic factor (BDNF) appears to play a crucial role in the reward response to drugs such as heroin. The primary objective of the present study was to examine epigenetic changes and serum levels of BDNF in patients undergoing different opiate-based maintenance treatments. We compared patients receiving treatment with either levomethadone (n = 55) or diamorphine (n = 28) with a healthy control group (n = 51). When comparing all subjects (patients and controls), BDNF serum levels showed a negative correlation with the BDNF IV promoter methylation rate (r = -0.177, p = 0.048). Furthermore, BDNF serum levels negatively correlated with Beck's Depression Inventory measurements (r = -0.177, p < 0.001). Patients receiving diamorphine maintenance treatment showed slightly decreased BDNF serum levels compared to healthy controls, whereas patients on levomethadone maintenance treatment with or without heroine co-use showed a pronounced decrease (analysis of covariance: control vs. levomethadone with and without heroine co-use: p < 0.0001, diamorphine vs. levomethadone with heroine co-use: p = 0.043, diamorphine vs. levomethadone without heroine co-use: p < 0.0001). According to these findings, methylation of the BDNF IV promoter showed the highest level in patients receiving levomethadone without heroine co-use (linear mixed model: control vs. levomethadone group without heroine co-use: p = 0.008, with heroin co-use: p = 0.050, diamorphine vs. levomethadone group with heroine co-use: p = 0.077 and without heroine co-use: p = 0.015.). For the first time, we show an epigenetic mechanism that may provide an explanation for mood destabilization in levomethadone maintenance treatment.
Topic(s):
Opioids & Substance Use See topic collection
4019
Eliminating Behavioral Health Disparities and Improving Outcomes for Racial and Ethnic Minority Populations
Type: Journal Article
Authors: K. Sanchez, R. Ybarra, T. Chapa, O. N. Martinez
Year: 2016
Publication Place: United States
Abstract: Integrated care holds promise for reducing mental health disparities for racial and ethnic minority groups, but studies are lacking. The authors consider critical components of effective integrated models for minority populations, including cultural and linguistic competence and a diverse workforce, and describe emerging best practices. To successfully implement integrated models into practice with minority populations will require guidance from communities, consumers and family members, and national experts.
Topic(s):
Healthcare Disparities See topic collection
4020
Eliminating disparities in youth substance use among Native Hawaiian, Micronesian, and sex and gender minorities: A qualitative needs assessment from interviews with public service leaders
Type: Journal Article
Authors: Bailey Monick, Davis Rehuher, Katarzyna Wilczek, Susana Helm
Year: 2022
Topic(s):
Education & Workforce See topic collection
,
Healthcare Disparities See topic collection
,
Opioids & Substance Use See topic collection