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The Literature Collection contains over 11,000 references for published and grey literature on the integration of behavioral health and primary care. Learn More

Use the Search feature below to find references for your terms across the entire Literature Collection, or limit your searches by Authors, Keywords, or Titles and by Year, Type, or Topic. View your search results as displayed, or use the options to: Show more references per page; Sort references by Title or Date; and Refine your search criteria. Expand an individual reference to View Details. Full-text access to the literature may be available through a link to PubMed, a DOI, or a URL. References may also be exported for use in bibliographic software (e.g., EndNote, RefWorks, Zotero).

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12257 Results
3721
Effectiveness of collaborative care in addressing depression treatment preferences among low-income Latinos
Type: Journal Article
Authors: M. Dwight-Johnson, I. T. Lagomasino, J. Hay, L. Zhang, L. Tang, J. M. Green, N. Duan
Year: 2010
Publication Place: United States
Abstract: OBJECTIVE: This study assessed treatment preferences among low-income Latino patients in public-sector primary care clinics and examined whether a collaborative care intervention that included patient education and allowed patients to choose between medication, therapy, or both would increase the likelihood that patients received preferred treatment. METHODS: A total of 339 Latino patients with probable depressive disorders were recruited; participants completed a baseline conjoint analysis preference survey and were randomly assigned to receive the intervention or enhanced usual care. At 16 weeks, a patient survey assessed depression treatment received during the study period. Logistic regression models were constructed to estimate treatment preferences, examine patient characteristics associated with treatment preferences, and examine patient characteristics associated with a match between stated preference and actual treatment received. RESULTS: The conjoint analysis preference survey showed that patients preferred counseling or counseling plus medication over antidepressant medication alone and that they preferred treatment in primary care over specialty mental health care, but they showed no significant preference for individual versus group treatment. Patients also indicated that individual education sessions, telephone sessions, transportation assistance, and family involvement were barrier reduction strategies that would enhance their likelihood of accepting treatment. Compared with patients assigned to usual care, those in the intervention group were 21 times as likely to receive preferred treatment. Among all participants, women, unemployed persons, those who spoke English, and those referred by providers were more likely to receive preferred treatment. CONCLUSIONS: Collaborative care interventions that include psychotherapy can increase the likelihood that Latino patients receive preferred care; however, special efforts may be needed to address preferences of working persons, men, and Spanish-speaking patients.
Topic(s):
Education & Workforce See topic collection
,
Healthcare Disparities See topic collection
3722
Effectiveness of collaborative stepped care for anxiety disorders in primary care: a pragmatic cluster randomised controlled trial
Type: Journal Article
Authors: A. Muntingh, C. van der Feltz-Cornelis, H. van Marwijk, P. Spinhoven, W. Assendelft, M. de Waal, H. Ader, A. van Balkom
Year: 2014
Publication Place: Switzerland
Abstract: BACKGROUND: Collaborative stepped care (CSC) may be an appropriate model to provide evidence-based treatment for anxiety disorders in primary care. METHODS: In a cluster randomised controlled trial, the effectiveness of CSC compared to care as usual (CAU) for adults with panic disorder (PD) or generalised anxiety disorder (GAD) in primary care was evaluated. Thirty-one psychiatric nurses who provided their services to 43 primary care practices in the Netherlands were randomised to deliver CSC (16 psychiatric nurses, 23 practices) or CAU (15 psychiatric nurses, 20 practices). CSC was provided by the psychiatric nurses (care managers) in collaboration with the general practitioner and a consultant psychiatrist. The intervention consisted of 3 steps, namely guided self-help, cognitive behavioural therapy and antidepressants. Anxiety symptoms were measured with the Beck Anxiety Inventory (BAI) at baseline and after 3, 6, 9 and 12 months. RESULTS: We recruited 180 patients with a DSM-IV diagnosis of PD or GAD, of whom 114 received CSC and 66 received usual primary care. On the BAI, CSC was superior to CAU [difference in gain scores from baseline to 3 months: -5.11, 95% confidence interval (CI) -8.28 to -1.94; 6 months: -4.65, 95% CI -7.93 to -1.38; 9 months: -5.67, 95% CI -8.97 to -2.36; 12 months: -6.84, 95% CI -10.13 to -3.55]. CONCLUSIONS: CSC, with guided self-help as a first step, was more effective than CAU for primary care patients with PD or GAD.
Topic(s):
Medically Unexplained Symptoms See topic collection
3723
Effectiveness of community mental health nurses in an integrated primary care service: An observational cohort study
Type: Journal Article
Authors: M. Kenwright, P. Fairclough, J. McDonald, L. Pickford
Year: 2024
Abstract:

BACKGROUND: The movement of community mental health nurses into primary care is important for the delivery of primary care integrated teams. There is little evidence or guidance on how integration should be implemented, or on the effectiveness of mental health nurses in primary care. OBJECTIVES: 1. Examine one method of integrating community mental health nurses in a primary care mental health service to identify factors that both facilitated and hindered integration. 2. Report on the outcomes of community mental health nurses in delivering problem-specific evidence-based psychological interventions in primary care. DESIGN: A naturalistic observational cohort study. SETTING: An integrated primary care mental health service in the UK North Midlands. PARTICIPANTS: 1,582 referrals from 1st April 2019 - 31st March 2022. METHOD: Anonymised patient records from routine treatment with community mental health nurses in an integrated primary care service were extracted and analysed to identify patient characteristics, content of treatment and outcomes. Features of service design were also examined to report on aids and barriers to primary care integration. RESULTS: Large and clinically significant pre to post treatment effect sizes of between 0.5 and 0.8 were observed in symptom reduction and functional improvement for patients treated by community mental health nurses for a range of mental health problems. Aids to integration were: A single line of clinical management and governance; shared training across all roles; a shared IT system/electronic appointment diary. Barriers to integration were: Different contract management structures, and different clinical IT systems across primary and secondary care. CONCLUSIONS: Integrating community mental health nurses into one primary care mental health service comprising different mental health professionals provided a single point of access to different mental health treatments. Primary care community mental health nurses delivered effective evidence-based psychological interventions in a stepped-care model that reduced demands on secondary care services.

Topic(s):
Education & Workforce See topic collection
3724
Effectiveness of disease management programs in depression: a systematic review
Type: Journal Article
Authors: E. Badamgarav, S. R. Weingarten, J. M. Henning, K. Knight, V. Hasselblad, A. J. Gano, J. J. Ofman
Year: 2003
Topic(s):
Key & Foundational See topic collection
3725
Effectiveness of Drug Dependence Treatment in HIV Prevention
Type: Journal Article
Authors: Michael Farrell, Linda Gowing, John Marsden, Walter Ling, Robert Ali
Year: 2005
Topic(s):
Opioids & Substance Use See topic collection
3726
Effectiveness of drug tests in outpatients starting opioid substitution therapy
Type: Journal Article
Authors: J. Dupouy, L. Dassieu, R. Bourrel, J. C. Poutrain, S. Bismuth, S. Oustric, M. Lapeyre-Mestre
Year: 2013
Publication Place: United States
Topic(s):
Opioids & Substance Use See topic collection
,
Financing & Sustainability See topic collection
3727
Effectiveness of Injectable Extended-Release Naltrexone vs Daily Buprenorphine-Naloxone for Opioid Dependence: A Randomized Clinical Noninferiority Trial
Type: Journal Article
Authors: L. Tanum, K. K. Solli, Z. E. Latif, J. S. Benth, A. Opheim, K. Sharma-Haase, P. Krajci, N. Kunoe
Year: 2017
Publication Place: United States
Abstract: Importance: To date, extended-release naltrexone hydrochloride has not previously been compared directly with opioid medication treatment (OMT), currently the most commonly prescribed treatment for opioid dependence. Objective: To determine whether treatment with extended-release naltrexone will be as effective as daily buprenorphine hydrochloride with naloxone hydrochloride in maintaining abstinence from heroin and other illicit substances in newly detoxified individuals. Design, Setting and Participants: A 12-week, multicenter, outpatient, open-label randomized clinical trial was conducted at 5 urban addiction clinics in Norway between November 1, 2012, and December 23, 2015; the last follow-up was performed on October 23, 2015. A total of 232 adult opioid-dependent (per DSM-IV criteria) individuals were recruited from outpatient addiction clinics and detoxification units and assessed for eligibility. Intention-to-treat analyses of efficacy end points were performed with all randomized participants. Interventions: Randomization to either daily oral flexible dose buprenorphine-naloxone, 4 to 24 mg/d, or extended-release naltrexone hydrochloride, 380 mg, administered intramuscularly every fourth week for 12 weeks. Main Outcomes and Measures: Primary end points (protocol) were the randomized clinical trial completion rate, the proportion of opioid-negative urine drug tests, and number of days of use of heroin and other illicit opioids. Secondary end points included number of days of use of other illicit substances. Safety was assessed by adverse event reporting. Results: Of 159 participants, mean (SD) age was 36 (8.6) years and 44 (27.7%) were women. Eighty individuals were randomized to extended-release naltrexone and 79 to buprenorphine-naloxone; 105 (66.0%) completed the trial. Retention in the extended-release naltrexone group was noninferior to the buprenorphine-naloxone group (difference, -0.1; with 95% CI, -0.2 to 0.1; P = .04), with mean (SD) time of 69.3 (25.9) and 63.7 (29.9) days, correspondingly (P = .33, log-rank test). Treatment with extended-release naltrexone showed noninferiority to buprenorphine-naloxone on group proportion of total number of opioid-negative urine drug tests (mean [SD], 0.9 [0.3] and 0.8 [0.4], respectively, difference, 0.1 with 95% CI, -0.04 to 0.2; P < .001) and use of heroin (mean difference, -3.2 with 95% CI, -4.9 to -1.5; P < .001) and other illicit opioids (mean difference, -2.7 with 95% CI, -4.6 to -0.9; P < .001). Superiority analysis showed significantly lower use of heroin and other illicit opioids in the extended-release naltrexone group. No significant differences were found between the treatment groups regarding most other illicit substance use. Conclusions and Relevance: Extended-release naltrexone was as effective as buprenorphine-naloxone in maintaining short-term abstinence from heroin and other illicit substances and should be considered as a treatment option for opioid-dependent individuals. Trial Registration: clinicaltrials.gov Identifier: NCT01717963.
Topic(s):
Opioids & Substance Use See topic collection
3728
Effectiveness of integrated care for older adults-based interventions on depressive symptoms: A systematic review and meta-analysis
Type: Journal Article
Authors: W. Liu, R. Qin, X. Zhang, G. Li, Y. Qiu, K. Huang, X. Li, L. Chen, J. Xiao
Year: 2024
Abstract:

AIM: To pool existing studies to assess the overall effectiveness of integrated care for older adults (ICOPE)-based interventions in improving depressive symptoms in older adults. DESIGN: A systematic review and meta-analysis. DATA SOURCES: Ten databases were systematically searched from inception to 15 July 2023 and the search was last updated on 2 September 2023. METHODS: Standardized mean difference (SMD) was calculated using random effects models. RoB 2 and GRADEpro GDT were used to assess the methodological quality and confidence in the cumulative evidence. Funnel plots, egger's test and begg's test were used to analyse publication bias. Sensitivity, subgroup and meta-regression analyses were performed to explore potential sources of heterogeneity. RESULTS: The results of 18 studies showed ICOPE-based interventions had a significant effect on improving depressive symptoms (SMD = -.84; 95% CI, -1.20 to -.3647; p < .001; 18 RCTs, 5010 participants; very low-quality evidence). Subgroup analysis showed the intervention group was characterized by mean age (70-80 years old), intervention duration between 6 to 12 months, gender (female <50%), non-frail older adults, depressed older adults and mixed integration appeared to be more effective. Sensitivity analysis found the results to be robust. CONCLUSION: ICOPE-based interventions may be a potentially effective alternative approach to reduce depressive symptoms in the older adults. IMPLICATIONS FOR THE PROFESSION AND/OR PATIENT CARE: Healthcare professionals are expected to use ICOPE as one of the interventions for depressive symptoms in older adults, and this ICOPE could provide more comprehensive care services for older adults to reduce depressive symptoms. IMPACT: ICOPE-based interventions may be a potentially effective alternative approach to reduce depressive symptoms in the older adults. ICOPE-based interventions had a significant effect on reducing depressive symptoms in the older adults. The intervention group characterized by mean age of older adults, intervention duration, gender ratio, health condition and integration types may influence the effect size. REPORTING METHOD: According to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PATIENT OR PUBLIC CONTRIBUTION: No Patient or Public Contribution.

Topic(s):
Healthcare Disparities See topic collection
3729
Effectiveness of Integrated Care for Older Pepole (ICOPE) in Improving Intrinsic Capacity in Older Adults: A Systematic Review and Meta-Analysis
Type: Journal Article
Authors: W. Liu, R. Qin, X. Zhang, G. Li, Y. Qiu, G. Zhang, L. Chen
Year: 2025
Abstract:

OBJECTIVE: Conduct a systematic review of existing studies on intrinsic capacity (IC) and a meta-analysis of studies to assess the overall effectiveness of ICOPE in improving IC in older adults. METHODS: Ten databases were systematically searched from inception to November 8, 2023, and the search was last updated on January 2, 2024. Randomised controlled trials (RCTs) were included. The main outcomes were IC (cognition, psychological, sensory, vitality and locomotion). RESULTS: The results showed ICOPE had a significant effect in improving cognitive function (SMD = 0.36; 95% CI, 0.17 to 0.56, p < 0.001, 12 RCTs, 7926 participants) and depressive symptoms (SMD = -0.70; 95% CI, -0.96 to -0.43, p < 0.001, 26 RCTs, 11,034 participants), but there was no statistically significant difference in improving locomotion (SMD = 0.16; 95% CI, -0.03 to 0.34, p = 0.098, 3 RCTs, 1580 participants). Meta-regression analysis shows that intervention duration should be paid attention to when the source of heterogeneity is discussed on the cognition. CONCLUSION: The results suggest that ICOPE may be a potentially effective approach to help improve the IC in older adults, showing significant potential for improving cognitive function and reducing depressive symptoms in particular. IMPLICATIONS FOR THE PROFESSION AND/OR PATIENT CARE: ICOPE is expected to provide effective strategies to enhance issues such as IC and may be an innovative way to improve the overall health of older adults. This result provides strong support for geriatric nursing practice and encourages the adoption of ICOPE as a viable nursing approach to promote healthy ageing.

Topic(s):
Healthcare Disparities See topic collection
3730
Effectiveness of integrated care for older pepole (ICOPE) in improving intrinsic capacity in older adults: A systematic review and meta‐analysis
Type: Journal Article
Authors: Wei Liu, Rixin Qin, Xueyan Zhang, Guichen Li, Yiming Qiu, Guangwei Zhang, Li Chen
Year: 2025
Topic(s):
Healthcare Disparities See topic collection
3731
Effectiveness of integrated primary and behavioral healthcare
Type: Journal Article
Authors: A. S. Lenz, Julia Dell'Aquila, Richard S. Balkin
Year: 2018
Topic(s):
Education & Workforce See topic collection
3732
Effectiveness of Integrating Suicide Care in Primary Care : Secondary Analysis of a Stepped-Wedge, Cluster Randomized Implementation Trial
Type: Journal Article
Authors: Angerhofer Richards, M. Cruz, C. Stewart, A. K. Lee, T. C. Ryan, B. K. Ahmedani, G. E. Simon
Year: 2024
Abstract:

BACKGROUND: Primary care encounters are common among patients at risk for suicide. OBJECTIVE: To evaluate the effectiveness of implementing population-based suicide care (SC) in primary care for suicide attempt prevention. DESIGN: Secondary analysis of a stepped-wedge, cluster randomized implementation trial. (ClinicalTrials.gov: NCT02675777). SETTING: 19 primary care practices within a large health care system in Washington State, randomly assigned launch dates. PATIENTS: Adult patients (aged ≥18 years) with primary care visits from January 2015 to July 2018. INTERVENTION: Practice facilitators, electronic medical record (EMR) clinical decision support, and performance monitoring supported implementation of depression screening, suicide risk assessment, and safety planning. MEASUREMENTS: Clinical practice and patient measures relied on EMR and insurance claims data to compare usual care (UC) and SC periods. Primary outcomes included documented safety planning after population-based screening and suicide risk assessment and suicide attempts or deaths (with self-harm intent) within 90 days of a visit. Mixed-effects logistic models regressed binary outcome indicators on UC versus SC, adjusted for randomization stratification and calendar time, accounting for repeated outcomes from the same site. Monthly outcome rates (percentage per 10 000 patients) were estimated by applying marginal standardization. RESULTS: During UC, 255 789 patients made 953 402 primary care visits and 228 255 patients made 615 511 visits during the SC period. The rate of safety planning was higher in the SC group than in the UC group (38.3 vs. 32.8 per 10 000 patients; rate difference, 5.5 [95% CI, 2.3 to 8.7]). Suicide attempts within 90 days were lower in the SC group than in the UC group (4.5 vs. 6.0 per 10 000 patients; rate difference, -1.5 [CI, -2.6 to -0.4]). LIMITATION: Suicide care was implemented in combination with care for depression and substance use. CONCLUSION: Implementation of population-based SC concurrent with a substance use program resulted in a 25% reduction in the suicide attempt rate in the 90 days after primary care visits. PRIMARY FUNDING SOURCE: National Institute of Mental Health.

Topic(s):
Measures See topic collection
3733
Effectiveness of medication assisted treatment for opioid use in prison and jail settings: A meta-analysis and systematic review
Type: Journal Article
Authors: K. E. Moore, W. Roberts, H. H. Reid, K. M. Z. Smith, L. M. S. Oberleitner, S. A. McKee
Year: 2019
Publication Place: United States
Topic(s):
Opioids & Substance Use See topic collection
3734
Effectiveness of medication for opioid use disorders in transition-age youth: A systematic review
Type: Journal Article
Authors: S. J. Becker, K. Scott, S. A. Helseth, K. J. Danko, E. M. Balk, I. J. Saldanha, G. P. Adam, D. W. Steele
Year: 2021
Publication Place: United States
Topic(s):
Healthcare Disparities See topic collection
,
Opioids & Substance Use See topic collection
3736
Effectiveness of Online Collaborative Care for Treating Mood and Anxiety Disorders in Primary Care: A Randomized Clinical Trial
Type: Journal Article
Authors: B. L. Rollman, Belnap B. Herbeck, K. Z. Abebe, M. B. Spring, A. J. Rotondi, S. D. Rothenberger, J. F. Karp
Year: 2018
Abstract: IMPORTANCE: Collaborative care for depression and anxiety is superior to usual care from primary care physicians for these conditions; however, challenges limit its provision in routine practice and at scale. Advances in technology may overcome these barriers but have yet to be tested. OBJECTIVE: To examine the effectiveness of combining an internet support group (ISG) with an online computerized cognitive behavioral therapy (CCBT) provided via a collaborative care program for treating depression and anxiety vs CCBT alone and whether providing CCBT in this manner is more effective than usual care. DESIGN, SETTING, AND PARTICIPANTS: In this 3-arm randomized clinical trial with blinded outcome assessments, primary care physicians from 26 primary care practices in Pittsburgh, Pennsylvania, referred 2884 patients aged 18 to 75 years in response to an electronic medical record prompt from August 2012 to September 2014. Overall, 704 patients (24.4%) met all eligibility criteria and were randomized to CCBT alone (n?=?301), CCBT+ISG (n?=?302), or usual care (n?=?101). Intent-to-treat analyses were conducted November 2015 to January 2017. INTERVENTIONS: Six months of guided access to an 8-session CCBT program provided by care managers who informed primary care physicians of their patients' progress and promoted patient engagement with our online programs. MAIN OUTCOMES AND MEASURES: Mental health-related quality of life (12-Item Short-Form Health Survey Mental Health Composite Scale) and depression and anxiety symptoms (Patient-Reported Outcomes Measurement Information System) at 6-month follow-up, with treatment durability assessed 6 months later. RESULTS: Of the 704 randomized patients, 562 patients (79.8%) were female, and the mean (SD) age was 42.7 (14.3) years. A total of 604 patients (85.8%) completed our primary 6-month outcome assessment. At 6-month assessment, 254 of 301 patients (84.4%) receiving CCBT alone started the program (mean [SD] sessions completed, 5.4 [2.8]), and 228 of 302 patients (75.5%) in the CCBT+ISG cohort logged into the ISG at least once, of whom 141 (61.8%) provided 1 or more comments or posts (mean, 10.5; median [range], 3 [1-306]). Patients receiving CCBT+ISG reported similar 6-month improvements in mental health-related quality of life, mood, and anxiety symptoms compared with patients receiving CCBT alone. However, compared with patients receiving usual care, patients in the CCBT alone cohort reported significant 6-month effect size improvements in mood (effect size, 0.31; 95% CI, 0.09-0.53) and anxiety (effect size, 0.26; 95% CI, 0.05-0.48) that persisted 6 months later, and completing more CCBT sessions produced greater effect size improvements in mental health-related quality of life and symptoms. CONCLUSIONS AND RELEVANCE: While providing moderated access to an ISG provided no additional benefit over guided CCBT at improving mental health-related quality of life, mood, and anxiety symptoms, guided CCBT alone is more effective than usual care for these conditions.
Topic(s):
HIT & Telehealth See topic collection
3737
Effectiveness of peer-supported computer-based CBT for depression among veterans in primary care
Type: Journal Article
Authors: Paul N. Pfeiffer, Brooke Pope, Marc Houck, Wendy Benn-Burton, Kara Zivin, Dara Ganoczy, H. M. Kim, Heather Walters, Lauren Emerson, C. B. Nelson, Kristen M. Abraham, Marcia Valenstein
Year: 2020
Topic(s):
Healthcare Disparities See topic collection
,
Measures See topic collection
3738
Effectiveness of Psychological and Educational Interventions to Prevent Depression in Primary Care: A Systematic Review and Meta-Analysis
Type: Journal Article
Authors: S. Conejo-Ceron, P. Moreno-Peral, A. Rodriguez-Morejon, E. Motrico, D. Navas-Campana, A. Rigabert, C. Martin-Perez, A. Rodriguez-Bayon, M. I. Ballesta-Rodriguez, J. D. Luna, J. Garcia-Campayo, M. Roca, J. A. Bellon
Year: 2017
Publication Place: United States
Topic(s):
General Literature See topic collection