Opioid Prescribing Guidelines Updated by CDC


As of November 4th, 2022, the Centers for Disease Control and Prevention (CDC) have updated their CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022 replacing the 2016 publication. This Guideline “provides recommendations for clinicians providing pain care, including those prescribing opioids, for outpatients [at least 18 years old] and includes recommendations for managing acute (duration of <1 month), subacute (duration of 1–3 months), and chronic (duration of >3 months) pain”[1].

The new guideline addresses four key areas:

  1. “Determining whether to initiate opioids for pain
  2. Selecting opioids and determining opioid dosages
  3. Deciding duration of initial opioid prescription and conducting follow-up, and
  4. Assessing risk and addressing potential harms of opioid use”1.

For more resources on prescribing opioids, please see the MAT for OUD Tools and Resources.


[1] Dowell D, Ragan KR, Jones CM, Baldwin GT, Chou R. CDC Clinical Practice Guideline for Prescribing Opioids for Pain  United States, 2022. MMWR Recomm Rep 2022;71(No. RR-3):1–95. Available from: http://dx.doi.org/10.15585/mmwr.rr7103a1. Accessed December 27, 2022.