Substance Use Tools & Resources
This collection of tools and resources is for providers, staff, and patients who offer or use services to address substance use, and other interested stakeholders. This collection was originally established following an environmental scan on implementing medication-assisted treatment (MAT) for opioid use disorder (OUD) in rural primary care. (See PDFs of Volume 1 (PDF - 609 KB) and Volume 2 (PDF - 1.3 MB) of that scan). Items have been continuously added to this collection since then, and the collection has expanded to cover substance use more broadly, rather than just MAT for OUD.
Sentinel Site Reports
Substance Use Disorder Treatment Legislation Database
2025 AMA Report on Substance Use and Treatment: Progress, Policy and Future Directions (PDF - 6.6 MB KB)
2025 National Guidelines for a Behavioral Health Coordinated System of Crisis Care (PDF - 1.6 MB KB)
This new publication provides guidance and highlight effective practices for crisis care services across the country. SAMHSA has identified the essential elements for an effective crisis continuum such that everyone in the nation has a robust system that meets their needs, one that includes “someone to contact, someone to respond, and a safe place for help.”
Behind the Numbers: Making Sense of Trends in the Drug Supply and Overdose Rates
Blueprint for a National Prevention Infrastructure for Mental, Emotional, and Behavioral Disorders
Buprenorphine Self-Start (PDF - 3.4 MB KB)
Challenges in Standardizing SUD Care Coordination (PDF - 309 KB KB)
Clinical Guidance for PrEP
This page from the Centers for Disease Control and Prevention (CDC) provides comprehensive guidance on Pre-Exposure Prophylaxis (PrEP) for HIV prevention.
