Literature Collection

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Grey Literature

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Opioids & SU

The Literature Collection contains over 10,000 references for published and grey literature on the integration of behavioral health and primary care. Learn More

Use the Search feature below to find references for your terms across the entire Literature Collection, or limit your searches by Authors, Keywords, or Titles and by Year, Type, or Topic. View your search results as displayed, or use the options to: Show more references per page; Sort references by Title or Date; and Refine your search criteria. Expand an individual reference to View Details. Full-text access to the literature may be available through a link to PubMed, a DOI, or a URL. References may also be exported for use in bibliographic software (e.g., EndNote, RefWorks, Zotero).

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421
A practice guide for continuous opioid therapy for refractory daily headache: patient selection, physician requirements, and treatment monitoring
Type: Journal Article
Authors: J. R. Saper, A. E. Lake III, P. A. Bain, M. J. Stillman, J. F. Rothrock, N. T. Mathew, R. L. Hamel, M. Moriarty, G. E. Tietjen
Year: 2010
Publication Place: United States
Abstract: OBJECTIVES: To provide a guide to the use and limitations of continuous opioid therapy (COT, or daily scheduled opioids) for refractory daily headache, based on the best available evidence and expert clinical experience. BACKGROUND: There has been a dramatic increase in opioid administration over the past 25 years, with limited evidence of efficacy for either pain reduction or increased function, and increasing evidence of adverse effects, including headache chronification. To date, there has been no consensus on headache-specific guidelines for selecting patients for COT, physician requirements, and treatment monitoring. METHODS: A multidisciplinary committee of physicians and allied health professionals with extensive experience and expertise in the administration of opioids to headache patients, undertook a review of the available evidence from the research and clinical literature (using the PubMed database for articles through December 2009) to develop headache-specific treatment recommendations. This guide reflects the opinions of its authors and is not an official document of the American Headache Society. RESULTS: The guide identifies factors that would qualify or disqualify the use of COT, including, determination of intractability prior to initiating COT, requisite experience of the prescriber, and requirements for a formal monitoring system to assess appropriate use, safety, efficacy, and functional impact. An appendix reviews the available evidence for efficacy of COT in chronic headache and noncancer pain, paradoxical effects (opioid-induced hyperalgesia, medication overuse headache, opioid-related reduction in triptan and nonsteroidal anti-inflammatory drug efficacy), other adverse effects (nausea and constipation, insomnia and sleep apnea, respiratory depression and sudden cardiac death, reductions in sex hormones, issues during pregnancy, neurocognitive functioning), and issues related to comorbid psychiatric disorders. CONCLUSIONS: Only a select and very limited group (estimate of 10-20%) of refractory headache patients who meet criteria for COT respond with convincing headache reduction and functional improvement over the long-term. Conservative and empirically based guidelines will help identify those patients for whom a COT trial may be appropriate, while protecting their welfare and safety.
Topic(s):
Opioids & Substance Use See topic collection
422
A pragmatic randomized controlled trial of a guided self-help intervention versus a waiting list control in a routine primary care mental health service
Type: Journal Article
Authors: Mike Lucock, Rebecca Kirby, Nigel Wainwright
Year: 2011
Publication Place: United Kingdom: British Psychological Society
Topic(s):
Education & Workforce See topic collection
423
A Preliminary Study Examining Nutritional Risk Factors, Body Mass Index, and Treatment Retention in Opioid-Dependent Patients
Type: Journal Article
Authors: R. A. Richardson, K. Wiest
Year: 2015
Publication Place: United States
Abstract: Poor nutritional health among opioid-dependent individuals is well established, yet no nutritional screening tool exists for this specific population. The utility of "Determine Your Nutritional Health" developed by the Nutrition Screening Initiative is considered. The study examines the questionnaire's relevance in patients beginning opioid dependence treatment at a methadone-assisted treatment program (N = 140) by examining nutritional risk factor prevalence, body mass index, and association between nutritional risk level and treatment retention. The majority of patients reported at least one nutritional risk factor (89 %) and 59 % were at high nutritional risk. Body mass index was not related to nutritional risk; however, a trend was identified between increasing nutritional risk and decreased retention in treatment. These preliminary findings suggest the need for incorporation of nutritional screening at intake in opioid treatment programs, consideration of the effect of dietary risk on treatment retention, and the potential utility of this screening tool.
Topic(s):
Opioids & Substance Use See topic collection
424
A Prescription Digital Therapeutic to Support Unsupervised Buprenorphine Initiation for Patients With Opioid Use Disorder: Protocol for a Proof-of-Concept Study
Type: Journal Article
Authors: H. Luderer, N. Enman, R. Gerwien, S. Braun, S. McStocker, X. Xiong, C. Koebele, C. Cannon, J. Glass, Y. Maricich
Year: 2023
Topic(s):
Opioids & Substance Use See topic collection
425
A Prescription for Action: Local Leadership in Ending the Opioid Crisis
Type: Report
Authors: National League of Cities, National Association of Counties
Year: 2016
Publication Place: Washington, DC
Topic(s):
Grey Literature See topic collection
,
Healthcare Policy See topic collection
,
Opioids & Substance Use See topic collection
Disclaimer:

This grey literature reference is included in the Academy's Literature Collection in keeping with our mission to gather all sources of information on integration. Grey literature is comprised of materials that are not made available through traditional publishing avenues. Often, the information from unpublished resources can be limited and the risk of bias cannot be determined.

426
A primary care approach to substance misuse
Type: Journal Article
Authors: B. Shapiro, D. Coffa, E. F. McCance-Katz
Year: 2013
Publication Place: United States
Abstract: Substance misuse is common among patients in primary care settings. Although it has a substantial health impact, physicians report low levels of preparedness to identify and assist patients with substance use disorders. An effective approach to office-based treatment includes a coherent framework for identifying and managing substance use disorders and specific strategies to promote behavior change. Brief validated screening tools allow rapid and efficient identification of problematic drug use, including prescription medication misuse. After a positive screening, a brief assessment should be performed to stratify patients into three categories: hazardous use, substance abuse, or substance dependence. Patients with hazardous use benefit from brief counseling by a physician. For patients with substance abuse, brief counseling is also indicated, with the addition of more intensive ongoing follow-up and reevaluation. In patients with substance dependence, best practices include a combination of counseling, referral to specialty treatment, and pharmacotherapy (e.g., drug tapering, naltrexone, buprenorphine, methadone). Comorbid mental illness and intimate partner violence are common in patients with substance use disorders. The use of a motivational rather than a confrontational communication style during screening, counseling, and treatment is important to improve patient outcomes.
Topic(s):
Opioids & Substance Use See topic collection
427
A primary care guide to bipolar depression treatment
Type: Journal Article
Authors: N. A. Youssef, E. Aquadro, A. Thomas, S. Brown, K. O'Connor, J. Hobbs, R. J. Bishnoi
Year: 2020
Publication Place: United States
Abstract:

Manage uncomplicated cases following guidelines on medical therapy and with adjunctive psychotherapy. Refer complicated and severe cases to Psychiatry.

Topic(s):
Education & Workforce See topic collection
,
Healthcare Disparities See topic collection
428
A primary care perspective of posttraumatic stress disorder for the Department of Veterans Affairs
Type: Journal Article
Authors: S. Ramaswamy, V. Madaan, F. Qadri, C. J. Heaney, T. C. North, P. R. Padala, S. P. Sattar, F. Petty
Year: 2005
Publication Place: United States
Abstract: Posttraumatic stress disorder (PTSD) is a major mental disorder associated with significant morbidity, psychosocial impairment, and disability. The diagnosis of PTSD can be missed in a primary care setting, as patients frequently present with somatic complaints or depression and are often reluctant to discuss their traumatic experiences. As recent studies of veterans returning from the Gulf War and the Iraqi War suggest high rates of PTSD, the U.S. Department of Veterans Affairs (VA) Hospitals are gearing up to face this challenge. It is important to screen these veterans for symptoms of PTSD and make an appropriate referral if required. In this article, we attempt to review PTSD with a special focus on the VA population. In addition to discussing the epidemiology, diagnosis, and treatment options for PTSD, we also suggest screening questions for both combat-related and military sexual trauma-related PTSD.
Topic(s):
General Literature See topic collection
429
A primary care perspective on prevailing assumptions about persistent medically unexplained physical symptoms
Type: Journal Article
Authors: I. M. Stanley, S. Peters, P. Salmon
Year: 2002
Publication Place: United States
Abstract: OBJECTIVE: To re-examine the widespread assumption that medically unexplained physical symptoms represent discrete syndromes resulting from somatization of mental illness. METHOD: Primary care patients (N = 223) with medically unexplained symptoms of at least one year's duration were recruited to a study of exercise therapy. Data gathered from patients, from their general practitioners, and from medical records were used to examine relationships between self-defined disability, symptoms, mental state, and use of health care. RESULTS: Levels of disability and health care use were both raised, but were only weakly correlated. While most patients were depressed and/or anxious, a minority (14 percent) were neither. Although mental state correlated with disability, health care use was unrelated to either. Among a wide range of recorded symptoms, few correlations were found to support the existence of discrete syndromes. Analysis of agreement between patients and their doctors in assigning symptoms to broadly defined "syndromes" appears to reflect collaboration that is largely expedient CONCLUSIONS: In this sample of primary care patients with persistent unexplained physical symptoms, we found little evidence of discrete somatic syndromes. The level of health care use is no indication of mental state or level of disability, and the findings are equally consistent with depression or anxiety being secondary to disability and its consequences as with them being primary. The observed collaboration between patients and their doctors carries the risk of shaping, reinforcing, and legitimizing dubious syndromes.
Topic(s):
Medically Unexplained Symptoms See topic collection
430
A Primary Care Prevention System for Behavioral Health: The Behavioral Health Annual Wellness Checkup
Type: Journal Article
Authors: M. Zimmermann, W. O'Donohue, C. Vechiu
Year: 2020
Publication Place: United States
Abstract:

Behavioral health problems are involved in the majority of primary care visits. These behavior disorders (e.g., depression, anxiety, smoking, insomnia, etc.) are costly, burdensome to both the patient and the healthcare system, and result in greater medical utilization/cost and poorer future health outcomes. Integrated behavioral healthcare has been proposed as a model for more efficiently addressing the burden of behavioral health problems. While this model has demonstrated some promise in the treatment of behavioral health problems, as well as in the reduction in costs and improvement in healthcare outcomes, the primary prevention of behavioral health problems in this delivery model has been relatively neglected. The present paper discusses the potential value of incorporating the prevention of behavioral health problems into the annual physical/wellness checkup and proposes a detailed system for how this might be accomplished. Limitations, future research, and costs associated with increased prevention in a primary care context are discussed.

Topic(s):
Financing & Sustainability See topic collection
,
Healthcare Disparities See topic collection
431
A Primary Care Prevention System for Behavioral Health: The Behavioral Health Annual Wellness Checkup
Type: Journal Article
Authors: M. Zimmermann, W. O'Donohue, C. Vechiu
Year: 2019
Publication Place: United States
Abstract: Behavioral health problems are involved in the majority of primary care visits. These behavior disorders (e.g., depression, anxiety, smoking, insomnia, etc.) are costly, burdensome to both the patient and the healthcare system, and result in greater medical utilization/cost and poorer future health outcomes. Integrated behavioral healthcare has been proposed as a model for more efficiently addressing the burden of behavioral health problems. While this model has demonstrated some promise in the treatment of behavioral health problems, as well as in the reduction in costs and improvement in healthcare outcomes, the primary prevention of behavioral health problems in this delivery model has been relatively neglected. The present paper discusses the potential value of incorporating the prevention of behavioral health problems into the annual physical/wellness checkup and proposes a detailed system for how this might be accomplished. Limitations, future research, and costs associated with increased prevention in a primary care context are discussed.
Topic(s):
Financing & Sustainability See topic collection
432
A Primary Care Prevention System for Behavioral Health: The Behavioral Health Annual Wellness Checkup
Type: Journal Article
Authors: M. Zimmermann, W. O'Donohue, C. Vechiu
Year: 2019
Publication Place: United States
Abstract: Behavioral health problems are involved in the majority of primary care visits. These behavior disorders (e.g., depression, anxiety, smoking, insomnia, etc.) are costly, burdensome to both the patient and the healthcare system, and result in greater medical utilization/cost and poorer future health outcomes. Integrated behavioral healthcare has been proposed as a model for more efficiently addressing the burden of behavioral health problems. While this model has demonstrated some promise in the treatment of behavioral health problems, as well as in the reduction in costs and improvement in healthcare outcomes, the primary prevention of behavioral health problems in this delivery model has been relatively neglected. The present paper discusses the potential value of incorporating the prevention of behavioral health problems into the annual physical/wellness checkup and proposes a detailed system for how this might be accomplished. Limitations, future research, and costs associated with increased prevention in a primary care context are discussed.
Topic(s):
Financing & Sustainability See topic collection
434
A Primary Care Response to COVID‐19 for Patients with an Opioid Use Disorder: Official Journal of the American Rural Health Association and the National Rural Health Care Association
Type: Journal Article
Authors: Gilmore Wilson Courtenay, Melinda Ramage, Blake Fagan E
Year: 2021
Publication Place: Washington
Topic(s):
Education & Workforce See topic collection
,
Healthcare Disparities See topic collection
,
Opioids & Substance Use See topic collection
435
A Primary Care Telehealth Pilot Program to Improve Access: Associations with Patients' Health Care Utilization and Costs
Type: Journal Article
Authors: K. Gujral, J . Y. Scott, L. Ambady, C. E. Dismuke-Greer, J. Jacobs, A. Chow, A. Oh, J. Yoon
Year: 2022
Abstract:

Background: The Veterans Health Administration (VHA) piloted an innovative video telehealth program called Virtual Integrated Multisite Patient Aligned Care Teams (V-IMPACT) in fiscal year (FY) 2014. V-IMPACT set up one regional "hub" site where primary care (PC) teams provided regular PC through telehealth services to patients in outlying "spoke" sites that experienced gaps in provider coverage. We evaluated associations between clinic-level adoption of V-IMPACT and patients' utilization and VHA's costs for primary, emergency, and inpatient care. Materials and Methods: This observational study used repeated cross-sections of 208,612 unique veteran patients assigned to a PC team in 22 V-IMPACT spoke sites from FY2013 to FY2018. V-IMPACT adoption in a spoke site was indicated if more than 1% of patients assigned to PC in a site used V-IMPACT services during the year. Association between V-IMPACT adoption and outcomes were assessed using mixed-effects models. Results: V-IMPACT adoption was associated with increased telehealth visits for PC (incidence rate ratio [IRR] = 2.42 [1.29 to 4.55]) and for primary care mental health integration (IRR = 7.25 [2.69 to 19.54]). V-IMPACT adoption was not associated with in-person visits, or with total visits (in-person plus video telehealth). V-IMPACT adoption was also not associated with acute hospital stays, emergency department visits, or VHA costs. Conclusions: Programs such as VHA's V-IMPACT can increase telehealth visits for PC, allowing successful transition across modalities and facilitating continuity of care without impacting total care. Programs should track substitution of in-person visits with telehealth visits and examine its effects on patients' health outcomes, satisfaction, and travel costs.

Topic(s):
Financing & Sustainability See topic collection
,
Healthcare Disparities See topic collection
,
HIT & Telehealth See topic collection
436
A Primary Care-Based Cognitive Behavioral Therapy Intervention for Long-Term Opioid Users With Chronic Pain : A Randomized Pragmatic Trial
Type: Journal Article
Authors: L. Debar, M. Mayhew, L. Benes, A. Bonifay, R. A. Deyo, C. R. Elder, F. J. Keefe, M. C. Leo, C. McMullen, A. Owen-Smith, D. H. Smith, C. M. Trinacty, W. M. Vollmer
Year: 2022
Publication Place: United States
Abstract:

BACKGROUND: Chronic pain is common, disabling, and costly. Few clinical trials have examined cognitive behavioral therapy (CBT) interventions embedded in primary care settings to improve chronic pain among those receiving long-term opioid therapy. OBJECTIVE: To determine the effectiveness of a group-based CBT intervention for chronic pain. DESIGN: Pragmatic, cluster randomized controlled trial. (ClinicalTrials.gov: NCT02113592). SETTING: Kaiser Permanente health care systems in Georgia, Hawaii, and the Northwest. PARTICIPANTS: Adults (aged ≥18 years) with mixed chronic pain conditions receiving long-term opioid therapy. INTERVENTION: A CBT intervention teaching pain self-management skills in 12 weekly, 90-minute groups delivered by an interdisciplinary team (behaviorist, nurse, physical therapist, and pharmacist) versus usual care. MEASUREMENTS: Self-reported pain impact (primary outcome, as measured by the PEGS scale [pain intensity and interference with enjoyment of life, general activity, and sleep]) was assessed quarterly over 12 months. Pain-related disability, satisfaction with care, and opioid and benzodiazepine use based on electronic health care data were secondary outcomes. RESULTS: A total of 850 patients participated, representing 106 clusters of primary care providers (mean age, 60.3 years; 67.4% women); 816 (96.0%) completed follow-up assessments. Intervention patients sustained larger reductions on all self-reported outcomes from baseline to 12-month follow-up; the change in PEGS score was -0.434 point (95% CI, -0.690 to -0.178 point) for pain impact, and the change in pain-related disability was -0.060 point (CI, -0.084 to -0.035 point). At 6 months, intervention patients reported higher satisfaction with primary care (difference, 0.230 point [CI, 0.053 to 0.406 point]) and pain services (difference, 0.336 point [CI, 0.129 to 0.543 point]). Benzodiazepine use decreased more in the intervention group (absolute risk difference, -0.055 [CI, -0.099 to -0.011]), but opioid use did not differ significantly between groups. LIMITATION: The inclusion of only patients with insurance in large integrated health care systems limited generalizability, and the clinical effect of change in scores is unclear. CONCLUSION: Primary care-based CBT, using frontline clinicians, produced modest but sustained reductions in measures of pain and pain-related disability compared with usual care but did not reduce use of opioid medication. PRIMARY FUNDING SOURCE: National Institutes of Health.

Topic(s):
Education & Workforce See topic collection
,
Healthcare Disparities See topic collection
,
Measures See topic collection
,
Opioids & Substance Use See topic collection
437
A primary care-public health partnership addressing homelessness, serious mental illness, and health disparities
Type: Journal Article
Authors: L. C. Weinstein, M. D. Lanoue, J. D. Plumb, H. King, B. Stein, S. Tsemberis
Year: 2013
Publication Place: United States
Abstract: BACKGROUND: People with histories of homelessness and serious mental illness experience profound health disparities. Housing First is an evidenced-based practice that is working to end homelessness for these individuals through a combination of permanent housing and community-based supports. METHODS: The Jefferson Department of Family and Community Medicine and a Housing First agency, Pathways to Housing-PA, has formed a partnership to address multiple levels of health care needs for this group. We present a preliminary program evaluation of this partnership using the framework of the patient-centered medical home and the "10 Essential Public Health Services." RESULTS: Preliminary program evaluation results suggest that this partnership is evolving to function as an integrated person-centered health home and an effective local public health monitoring system. CONCLUSION: The Pathways to Housing-PA/Jefferson Department of Family and Community Medicine partnership represents a community of solution, and multiple measures provide preliminary evidence that this model is feasible and can address the "grand challenges" of integrated community health services.
Topic(s):
Healthcare Disparities See topic collection
,
Medical Home See topic collection
438
A Primary Mental Health Care Model for Advanced Practicum Training in a University Health Clinic
Type: Journal Article
Authors: Jennifer S. Funderburk, Robyn L. Fielder
Year: 2013
Publication Place: US
Topic(s):
Education & Workforce See topic collection
439
A primary mental health programme in Eastern Province, Saudi Arabia, 2003-2013
Type: Journal Article
Authors: Abdullah Dukhail Al-Khathami, Latifa Saleh Al-Harbi, Saleh Mohammed AlSalehi, Khalid AbduRahman Al-Turki, Mohammed Ali AlZahrani, Nawaf Abdullah Alotaibi, Mahdi S. Abumadini
Year: 2013
Topic(s):
General Literature See topic collection
440
A Primer on Antagonist-Based Treatment of Opioid Use Disorder in the Office Setting
Type: Web Resource
Authors: Adam Bisaga
Year: 2017
Topic(s):
Grey Literature See topic collection
,
Education & Workforce See topic collection
,
Opioids & Substance Use See topic collection
Disclaimer:

This grey literature reference is included in the Academy's Literature Collection in keeping with our mission to gather all sources of information on integration. Grey literature is comprised of materials that are not made available through traditional publishing avenues. Often, the information from unpublished resources can be limited and the risk of bias cannot be determined.