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Opioids & SU

The Literature Collection contains over 11,000 references for published and grey literature on the integration of behavioral health and primary care. Learn More

Use the Search feature below to find references for your terms across the entire Literature Collection, or limit your searches by Authors, Keywords, or Titles and by Year, Type, or Topic. View your search results as displayed, or use the options to: Show more references per page; Sort references by Title or Date; and Refine your search criteria. Expand an individual reference to View Details. Full-text access to the literature may be available through a link to PubMed, a DOI, or a URL. References may also be exported for use in bibliographic software (e.g., EndNote, RefWorks, Zotero).

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12771 Results
3521
Diagnosis of somatisation: effect of an educational intervention in a cluster randomised controlled trial
Type: Journal Article
Authors: M. Rosendal, F. Bro, P. Fink, K. S. Christensen, F. Olesen
Year: 2003
Publication Place: England
Abstract: BACKGROUND: Somatisation is highly prevalent in primary care (present in 25% of visiting patients) but often goes unrecognised. Non-recognition may lead to ineffective treatment, risk of iatrogenic harm, and excessive use of healthcare services. AIM: To examine the effect of training on diagnosis of somatisation in routine clinical practice by general practitioners (GPs). DESIGN OF STUDY: Cluster randomised controlled trial, with practices as the randomisation unit. SETTING: Twenty-seven general practices (with a total of 43 GPs) in Vejle County, Denmark. METHOD: Intervention consisted of a multifaceted training programme (the TERM [The Extended Reattribution and Management] model). Patients were enrolled consecutively over a period of 13 working days. Psychiatric morbidity was assessed by means of a screening questionnaire. GPs categorised their diagnoses in another questionnaire. The primary outcome was GP diagnosis of somatisation and agreement with the screening questionnaire. RESULTS: GPs diagnosed somatisation less frequently than had previously been observed, but there was substantial variation between GPs. The difference between groups in the number of diagnoses of somatisation failed to reach the 5% significance (P = 0.094). However, the rate of diagnoses of medically unexplained physical symptoms was twice as high in the intervention group as in the control group (7.7% and 3.9%, respectively, P = 0.007). Examination of the agreement between GPs' diagnoses and the screening questionnaire revealed no significant difference between groups. CONCLUSION: Brief training increased GPs' awareness of medically unexplained physical symptoms. Diagnostic accuracy according to a screening questionnaire remained unaffected but was difficult to evaluate, as there is no agreement on a gold standard for somatisation in general practice.
Topic(s):
Medically Unexplained Symptoms See topic collection
3522
Diagnosis of somatoform disorders in primary care: Diagnostic agreement, predictors, and comaprisons with depression and anxiety
Type: Journal Article
Authors: Katharina Piontek, Meike Shedden-Mora, Maria Gladigau, Amina Kuby, Bernd Lowe
Year: 2018
Topic(s):
Education & Workforce See topic collection
,
Medically Unexplained Symptoms See topic collection
3523
Diagnostic accuracy and adequacy of treatment of depressive and anxiety disorders: A comparison of primary care and specialized care patients
Type: Journal Article
Authors: J. I. Castro-Rodriguez, E. Olariu, C. Garnier-Lacueva, L. M. Martin-Lopez, V. Perez-Sola, J. Alonso, C. G. Forero, INSAyD investigators
Year: 2014
Topic(s):
General Literature See topic collection
3524
Diagnostic accuracy and factorial structure of the questionnaire for the assessment of depression symptoms in primary care (DESY-PC)
Type: Journal Article
Authors: C. Teusen, A. Hapfelmeier, M. Bühner, P. Sterner, L. Schäffler, P. Beigel, V. von Schrottenberg, J. Gensichen, K. Linde, A. Schneider
Year: 2025
Abstract:

INTRODUCTION: The general practitioners' (GP) approach to diagnosing depression has not yet been included in depression questionnaires. Therefore, the 'Questionnaire for the assessment of DEpression SYmptoms in Primary Care' (DESY-PC) has been developed. The DESY-PC consists of two parts, comprising the patient's perspective and psychiatric diagnostic criteria (DESY-PAT), and additionally the GP's heuristics and knowledge of patients (DESY-GP). The aim was to investigate the diagnostic accuracy and factor structure of the DESY-PC. METHODS: A multicentre diagnostic accuracy study was conducted in ten practices. Patients completed the DESY-PAT and PHQ-9 (Patient Health Questionnaire-9), while their GPs completed the DESY-GP. The Structured Clinical Interview for DSM-V disorders (SCID-V-CV) was used as reference standard. Sensitivity, specificity, receiver operating characteristic curves (ROC) and area under the curve (AUC) values were calculated to determine the diagnostic accuracy of the DESY-PC and PHQ-9. Factorial validity was assessed. RESULTS: 435 patients (mean age 47.6 years, 60.1% female, prevalence of depression 15.9%) were analysed. The diagnostic accuracy of the DESY-PAT (AUC=0.862, 95% Confidence Interval 0.815-0.908) was significantly higher (p<0.001) than that of PHQ-9 (AUC=0.821, 0.764-0.878). The diagnostic accuracy increased further when DESY-PAT was combined with DESY-GP for the overall questionnaire DESY-PC (AUC=0.874, 0.834-0.914). Goodness of fit indices indicated a plausible fit for the DESY-PC. CONCLUSIONS: Incorporating the GP's heuristics, judgement and knowledge of the patient contributes to a more accurate diagnosis. The DESY-PC integrates the GP's perspective, patient-specific factors, and psychiatric criteria into the diagnostic assessment, which might contribute to improved diagnostic decision-making in primary care.

Topic(s):
Measures See topic collection
3525
Diagnostic accuracy of a two-item Drug Abuse Screening Test (DAST-2)
Type: Journal Article
Authors: Q. Q. Tiet, Y. E. Leyva, R. H. Moos, B. Smith
Year: 2017
Publication Place: England
Abstract: OBJECTIVE: Drug use is prevalent and costly to society, but individuals with drug use disorders (DUDs) are under-diagnosed and under-treated, particularly in primary care (PC) settings. Drug screening instruments have been developed to identify patients with DUDs and facilitate treatment. The Drug Abuse Screening Test (DAST) is one of the most well-known drug screening instruments. However, similar to many such instruments, it is too long for routine use in busy PC settings. This study developed and validated a briefer and more practical DAST for busy PC settings. METHOD: We recruited 1300 PC patients in two Department of Veterans Affairs (VA) clinics. Participants responded to a structured diagnostic interview. We randomly selected half of the sample to develop and the other half to validate the new instrument. We employed signal detection techniques to select the best DAST items to identify DUDs (based on the MINI) and negative consequences of drug use (measured by the Inventory of Drug Use Consequences). Performance indicators were calculated. RESULTS: The two-item DAST (DAST-2) was 97% sensitive and 91% specific for DUDs in the development sample and 95% sensitive and 89% specific in the validation sample. It was highly sensitive and specific for DUD and negative consequences of drug use in subgroups of patients, including gender, age, race/ethnicity, marital status, educational level, and posttraumatic stress disorder status. CONCLUSIONS: The DAST-2 is an appropriate drug screening instrument for routine use in PC settings in the VA and may be applicable in broader range of PC clinics.
Topic(s):
Measures See topic collection
,
Opioids & Substance Use See topic collection
3526
Dialing for doctors: Secret shopper study of Arizona methadone and buprenorphine providers, 2022
Type: Journal Article
Authors: B. E. Meyerson, D. Treiber, B. R. Brady, K. Newgass, K. Bondurant, K. G. Bentele, S. Samorano, C. Arredondo, N. Stavros
Year: 2024
Topic(s):
Opioids & Substance Use See topic collection
,
Healthcare Disparities See topic collection
3527
DIAMOND for Depression
Type: Web Resource
Authors: Institute for Clinical Systems Improvement
Year: 2013
Topic(s):
Grey Literature See topic collection
Disclaimer:

This grey literature reference is included in the Academy's Literature Collection in keeping with our mission to gather all sources of information on integration. Grey literature is comprised of materials that are not made available through traditional publishing avenues. Often, the information from unpublished resources can be limited and the risk of bias cannot be determined.

3528
Diamorphine assisted treatment in Middlesbrough: a UK drug treatment case study
Type: Journal Article
Authors: Hannah Louise Poulter, Helen Moore, Rob Crow, Danny Ahmed, Tammi Walker
Year: 2024
Topic(s):
Opioids & Substance Use See topic collection
3529
Did Arkansas' Medicaid Patient-Centered Medical Home Program Have Spillover Effects on Commercially Insured Enrollees?
Type: Journal Article
Authors: Jesse M. Hinde, Nathan West, Samuel J. Arbes III, Marianne Kluckman, Suzanne L. West
Year: 2020
Publication Place: Thousand Oaks, California
Topic(s):
Education & Workforce See topic collection
,
Financing & Sustainability See topic collection
,
Medical Home See topic collection
3530
Differences between soldiers, with and without emotional distress, in number of primary care medical visits and type of presenting complaints
Type: Journal Article
Authors: A. D. Heymann, Y. Shilo, A. Tirosh, L. Valinsky, S. Vinker
Year: 2007
Publication Place: Israel
Abstract: BACKGROUND: In 2003 a total of 43 soldiers in the Israel Defense Forces committed suicide; only 20% of them were known to the IDF mental health services. Somatic symptoms are often the only presentation of emotional distress during the primary care visit and may be the key to early identification and treatment. OBJECTIVES: To examine whether the information in the medical records of soldiers can be used to identify those suffering from anxiety, affective or somatoform disorder. METHODS: We conducted a case-control study using the information in the electronic medical records of soldiers who during their 3 year service developed affective disorder, anxiety, or somatoform disorder. A control group was matched for recruitment date, type of unit and occupation in the service, and the Performance Prediction Score. The number and reasons for physician visits were collated. RESULTS: The files of 285 soldiers were examined: 155 cases and 130 controls. The numbers of visits (mean +/- SD) during the 3 and 6 month periods in the case and control groups were 4.7 +/- 3.3 and 7.1 +/- 5.0, and 4.1 +/- 2.9 and 5.9 +/- 4.6 respectively. The difference was statistically significant only for the 6 month period (P < 0.05). The variables that remained significant, after stepwise multivariate regression were the Performance Prediction Score and the presenting complaints of back pain and diarrhea. CONCLUSIONS: These findings may spur the development of a computer-generated warning for the primary care physician who will then be able to interview his or her patient appropriately and identify mental distress earlier.
Topic(s):
HIT & Telehealth See topic collection
3531
Differences in benefits of office based opioid treatment: Secondary analyses across sub‐groups in the proud randomized controlled implementation trial
Type: Journal Article
Authors: Katharine A. Bradley, Noorie Hyun, Abisola Idu, Onchee Yu, Jennifer F. Bobb, Paige D. Wartko, Zoe Weinstein, Abigail G. Matthews, Jennifer McCormack, Amy K. Lee, Jeffrey H. Samet
Year: 2025
Topic(s):
Opioids & Substance Use See topic collection
,
Education & Workforce See topic collection
3532
Differences in buprenorphine prescribing readiness among primary care professionals with and without X-waiver training in the US
Type: Journal Article
Authors: B. Franz, L . Y. Dhanani, O. T. Hall, D. L. Brook, J. E. Simon, W. C. Miller
Year: 2023
Topic(s):
Opioids & Substance Use See topic collection
,
Education & Workforce See topic collection
,
Healthcare Policy See topic collection
3533
Differences in health care costs between two social health support programs: findings from a randomized social health integration pilot program
Type: Journal Article
Authors: A. Mahmud, M. C. Brown, C. C. Lewis, I. J. Ornelas, R. Pardee, S. Mun, A. Piccorelli, E. O. Westbrook, H. D. Haan, E. S. Wong
Year: 2025
Abstract:

INTRODUCTION: More health systems are implementing strategies to understand and address patient social health, also known as social health integration. We examine the impact of a pilot social health integration program in two primary care clinics in an integrated health care system on health care costs. METHODS: We randomized 534 patients who reported any social need between October 2022 - January 2023 to receive support from a centralized Connections Call Center (CCC) or clinic-based Community Resource Specialists (CRS). We used administrative and claims data to compare costs between programs incurred by the health care system over 9 months. Using an intent-to-treat approach, we used two-part models to estimate costs for behavioral health, emergency department, inpatient admissions, and urgent care. We estimated single-part models using generalized linear models for primary care, specialty care, and total costs. Our secondary as-treated analyses compared costs among those who received support from CRS to those who did not. RESULTS: Unadjusted results showed no significant differences between CRS and CCC participants. Adjusted findings showed that CRS participants had $286 higher primary care costs than CCC participants (95% CI: $63.61, $508.89). As-treated findings showed that those who received CRS assistance had $2,356 more specialty care costs (95% CI: $229, $4,482) than those who did not. CONCLUSIONS: Observed changes in primary and specialty care costs may be a result of increasing engagement with the health system that could support patients in managing their health and prevent avoidable utilization in the long-term. These findings can help inform others who are interested in adopting similar primary care interventions.

Topic(s):
Financing & Sustainability See topic collection
,
Education & Workforce See topic collection
3534
Differences in Healthcare Utilization Across 2 Social Health Support Modalities: Results From a Randomized Pilot Evaluation
Type: Journal Article
Authors: A. Mahmud, E. S. Wong, C. C. Lewis, I. J. Ornelas, R. Wellman, R. Pardee, S. Mun, A. Piccorelli, E. O. Westbrook, H. D. Haan, M. C. Brown
Year: 2025
Abstract:

INTRODUCTION: The aim of this study was to assess differences in utilization outcomes among patients with social needs as part of a pilot social health integration program in 2 clinics in an integrated health system in the Pacific Northwest. METHODS: Patients who reported social needs between October 2022 and January 2023 were randomized to receive support from either local, clinic-based community resource specialists or a centralized Connections Call Center. The authors used administrative and claims data for 534 participants to compare the following utilization outcomes between arms over 9 months after randomization: primary care encounters, specialty care encounters, behavioral health encounters, emergency department encounters, inpatient admissions, urgent care encounters, and secure patient messages. Using an intent-to-treat approach, the authors used negative binomial regression models to compare visit counts and logistic regression to estimate differences in the probability of any emergency department visit or inpatient admissions between groups. The authors conducted secondary as-treated analyses comparing participants who received resource information from community resource specialists with those who did not. RESULTS: Unadjusted results showed no statistically significant differences between community resource specialists and Connections Call Center. Adjusted results showed that community resource specialist participants received 1.04 more primary care encounters than Connections Call Center participants (95% CI=0.336, 1.746). As-treated results showed that participants who received support from community resource specialists had higher counts of primary care encounters, specialty care encounters, and patient messages than those who did not. CONCLUSIONS: Beyond social needs navigation, clinic-based supports may be better integrated with care teams to provide ongoing support for patients' medical needs. Findings from this primary care social health pilot program showed that local, clinic-based support was associated with greater outpatient utilization than a call center support.

Topic(s):
Education & Workforce See topic collection
3535
Differences in Medicaid expansion effects on buprenorphine treatment utilization by county rurality and income: A pharmacy data claims analysis from 2009-2018
Type: Journal Article
Authors: O. K. Golan, F. Sheng, A. W. Dick, M. Sorbero, D. J. Whitaker, B. Andraka-Christou, T. Pigott, A. J. Gordon, B. D. Stein
Year: 2023
Topic(s):
Opioids & Substance Use See topic collection
,
Healthcare Policy See topic collection
,
Financing & Sustainability See topic collection
,
Healthcare Disparities See topic collection
3536
Differences in medical care expenditures for adults with depression compared to adults with major chronic conditions
Type: Journal Article
Authors: I. Z. Lurie, L. M. Manheim, D. D. Dunlop
Year: 2009
Publication Place: Italy
Abstract: BACKGROUND: Approximately 17.1 million adults report having a major depressive episode in 2004 which represents 8% of the adult population in the U.S. Of these, more than one-third did not seek treatment. In spite of the large and extensive literature on the cost of mental health, we know very little about the differences in out-of-pocket expenditures between adults with depression and adults with other major chronic disease and the sources of those expenditures. AIMS: For persons under age 65, compare total and out-of-pocket expenditures of those with depression to non-depressed individuals who have another major chronic disease. METHODS: This study uses two linked, nationally representative surveys, the 1999 National Health Interview Survey (NHIS) and the 2000 Medical Expenditure Panel Survey (MEPS), to identify the population of interest. Depression was systematically assessed using a short form of the World Health Organization's (WHO) Composite International Diagnostic Interview--Short Form (CIDI-SF). To control for differences from potentially confounding factors, we matched depressed cases to controls using propensity score matching. RESULTS: We estimate that persons with depression have about the same out-of-pocket expenditures while having 11.8% less total medical expenditures (not a statistically significant difference) compared to non-depressed individuals with at least one chronic disease. DISCUSSION: High out-of-pocket expenditures are a concern for individuals with chronic diseases. Our study shows that those with depression have comparable out-of-pocket expenses to those with other chronic diseases, but given their lower income levels, this may result in a more substantial financial burden. IMPLICATION FOR POLICY: High out-of-pocket expenditures are a concern for individuals with depression and other chronic diseases. For both depressed individuals and non-depressed individuals with other chronic diseases, prescription drug expenditures contribute most to out-of-pocket expenses. Given the important role medications play in treatment of depression, high copayment rates are a concern for limiting compliance with appropriate treatment.
Topic(s):
Financing & Sustainability See topic collection
,
Key & Foundational See topic collection
3537
Differences in patients' perceived helpfulness of depression treatment provided by general medical providers and specialty mental health providers
Type: Journal Article
Authors: S. J. Kuramoto-Crawford, B. Han, L. Jacobus-Kantor, R. Mojtabai
Year: 2015
Publication Place: United States
Abstract: OBJECTIVE: This study examined the differences in the level of perceived helpfulness of treatments received for a major depressive episode (MDE) from a general medical provider only, a specialty mental health provider only or both. METHOD: This study examined a sample of 8900 respondents from the 2008-2012 National Survey on Drug Use and Health aged 18-64 who had past 12-month MDE (based on criteria specified in the Diagnostic and Statistical Manual of Mental Disorders, Fourth edition) and received treatment for depression. Generalized ordered logistic regression analyses were conducted to estimate the association between the type of treatment providers and perceived helpfulness of depression treatment. RESULTS: Adults who received depression treatment from either specialty mental health providers alone or from both specialty mental health providers and general medical providers in the past year were more likely to report that treatment helped them. The differences persisted after adjusting for sociodemographic characteristics, comorbid health conditions, receipt of depression medication and severity of depression (adjusted odds ratios across level of perceived helpfulness ranged from 1.63 to 3.96). CONCLUSIONS: This finding calls for greater attention to factors associated with provider type and organizational context that may contribute to differences in perceived helpfulness of depression treatment.
Topic(s):
Education & Workforce See topic collection
,
Healthcare Disparities See topic collection
3538
Differences in perceived clinical knowledge uptake among health profession students and licensed clinicians receiving buprenorphine waiver training in Oregon
Type: Journal Article
Authors: J. L. Robbins, K. Bonuck, P. Thuillier, C. Buist, P. A. Carney
Year: 2022
Publication Place: United States
Abstract:

Background: Addressing the opioid crisis requires an understanding of how to train both health professional students and practicing clinicians on medications for opioid use disorder (mOUD). We designed a robust evaluation instrument to assess the impact of training on perceived clinical knowledge in these different categories of learners. Methods: We enrolled 3rd and 4th year medical, physician assistant (PA), and nurse practitioner (NP) students, as well as practicing PAs, NPs, and physicians to undertake the Drug Addiction Treatment Act (DATA) Waiver Training for mOUD. We designed and implemented a cross-sectional survey to assess perceived change in clinical knowledge as a result of training in opioid use disorder and satisfaction with training. Results: Twenty-one MD/DO and 45 NP/PA students, and 24 practicing MD/DO and 27 NP/PAs completed the survey. Among health professional students (n = 66) and practicing clinicians (n =51), perceived clinical knowledge scores increased significantly (p < 0.001) for all 13 variables. Program evaluation scores for the buprenorphine waiver training were high with no statistical differences between students and practicing clinicians. Overall, the majority of participants indicated they would recommend the training to a colleague (Students' score = 4.84; practicing clinician scores = 4.53; scale = strongly disagree = 1 to strongly agree = 5). Conclusions: Our novel instrument allowed us to determine that the implementation of buprenorphine waiver trainings for health professional students and practicing clinicians leads to significant increases in perceived knowledge, interest and confidence in diagnosing and treating OUD. Although the buprenorphine waiver can now be obtained without training, many waivered providers still do not prescribe buprenorphine; integrating training into medical, NP, and PA curriculum for students and offering the training to practicing clinicians may increase confidence and uptake of mOUD.

Topic(s):
Education & Workforce See topic collection
,
Measures See topic collection
,
Opioids & Substance Use See topic collection
3539
Differences in Perceptions of and Practices Regarding Treatment of Alcohol Use Disorders Among VA Primary Care Providers in Urban and Rural Clinics
Type: Journal Article
Authors: Jessica P. Young, Carol E. Achtmeyer, Kara M. Bensley, Eric J. Hawkins, Emily C. Williams
Year: 2018
Publication Place: Washington
Topic(s):
Education & Workforce See topic collection
,
Healthcare Disparities See topic collection
,
Opioids & Substance Use See topic collection
3540
Differences in Substance Use and Harm Reduction Practices by Race and Ethnicity: Rhode Island Harm Reduction Surveillance System, 2021-2022
Type: Journal Article
Authors: M. Rodriguez, M. McKenzie, H. McKee, E. M. Ledingham, K. John, J. Koziol, B. D. Hallowell
Year: 2024
Topic(s):
Opioids & Substance Use See topic collection
,
Healthcare Disparities See topic collection