TY - JOUR
KW - Antidepressive Agents/therapeutic use
KW - Body Image
KW - Cognitive Therapy
KW - Combined Modality Therapy
KW - Conversion Disorder/diagnosis/psychology/therapy
KW - Delusions/diagnosis/psychology/therapy
KW - Hypochondriasis/diagnosis/psychology/therapy
KW - Primary Health Care
KW - Randomized Controlled Trials as Topic
KW - Somatoform Disorders/diagnosis/psychology/therapy
KW - Treatment Outcome
AU - K. Kroenke
A1 - 
AB - OBJECTIVE: To review the evidence from randomized clinical trials (RCTs) that have focused on the treatment of patients with Diagnostic and Statistical Manual of Mental Disorders, 4(th) Edition (DSM-IV) somatoform disorders. Although somatoform disorders are among the most common mental disorders presenting in the general medical setting, the strength of evidence for specific treatments has not been well synthesized. METHODS: MEDLINE search of articles published in English from 1966 to 2006, using the following search terms: randomized clinical trial, somatoform disorders, somatization disorder, undifferentiated somatoform disorder, hypochrondriasis, conversion disorder, pain disorder, and body dysmorphic disorder. RESULTS: A total of 34 RCTs involving 3922 patients were included. Two thirds of the studies involved somatization disorder (n = 4 studies) and lower threshold variants, such as abridged somatization disorder (n = 9) and medically unexplained symptoms (n = 10). Cognitive behavioral therapy (CBT) was effective in most studies (11 of 13), as were antidepressants in a small number (4 of 5) of studies. RCTs examining a variety of other treatments showed benefit in half (8 of 16) of the studies, the most consistent evidence existing for a consultation letter to the primary care physician. Effective treatments have been established for all somatoform disorders except conversion disorder (1 of 3 studies showing benefit) and pain disorder (no studies reported). CONCLUSION: CBT is the best established treatment for a variety of somatoform disorders, with some benefit also demonstrated for a consultation letter to the primary care physician. Preliminary but not yet conclusive evidence exists for antidepressants.
BT - Psychosomatic medicine
C5 - Medically Unexplained Symptoms
CP - 9
CY - United States
DO - 10.1097/PSY.0b013e31815b00c4
IS - 9
JF - Psychosomatic medicine
N2 - OBJECTIVE: To review the evidence from randomized clinical trials (RCTs) that have focused on the treatment of patients with Diagnostic and Statistical Manual of Mental Disorders, 4(th) Edition (DSM-IV) somatoform disorders. Although somatoform disorders are among the most common mental disorders presenting in the general medical setting, the strength of evidence for specific treatments has not been well synthesized. METHODS: MEDLINE search of articles published in English from 1966 to 2006, using the following search terms: randomized clinical trial, somatoform disorders, somatization disorder, undifferentiated somatoform disorder, hypochrondriasis, conversion disorder, pain disorder, and body dysmorphic disorder. RESULTS: A total of 34 RCTs involving 3922 patients were included. Two thirds of the studies involved somatization disorder (n = 4 studies) and lower threshold variants, such as abridged somatization disorder (n = 9) and medically unexplained symptoms (n = 10). Cognitive behavioral therapy (CBT) was effective in most studies (11 of 13), as were antidepressants in a small number (4 of 5) of studies. RCTs examining a variety of other treatments showed benefit in half (8 of 16) of the studies, the most consistent evidence existing for a consultation letter to the primary care physician. Effective treatments have been established for all somatoform disorders except conversion disorder (1 of 3 studies showing benefit) and pain disorder (no studies reported). CONCLUSION: CBT is the best established treatment for a variety of somatoform disorders, with some benefit also demonstrated for a consultation letter to the primary care physician. Preliminary but not yet conclusive evidence exists for antidepressants.
PP - United States
PY - 2007
SN - 1534-7796; 0033-3174
SP - 881
EP - 888
EP - 
T1 - Efficacy of treatment for somatoform disorders: a review of randomized controlled trials
T2 - Psychosomatic medicine
TI - Efficacy of treatment for somatoform disorders: a review of randomized controlled trials
U1 - Medically Unexplained Symptoms
U2 - 18040099
U3 - 10.1097/PSY.0b013e31815b00c4
VL - 69
VO - 1534-7796; 0033-3174
Y1 - 2007
ER -