TY - JOUR KW - Adult KW - Buprenorphine/administration & dosage KW - Criminals/psychology KW - Female KW - Humans KW - Male KW - Middle Aged KW - Naloxone/administration & dosage KW - office visits KW - Opioid-Related Disorders/drug therapy/psychology KW - Primary Health Care/methods KW - Socioeconomic Factors KW - Treatment Outcome KW - Young Adult AU - E. A. Wang AU - B. A. Moore AU - L. E. Sullivan AU - D. A. Fiellin A1 - AB - BACKGROUND: Behaviors associated with opioid dependence often involve criminal activity, which can lead to incarceration. The impact of a history of incarceration on outcomes in primary care office-based buprenorphine/naloxone is not known. OBJECTIVE: The purpose of this study is to determine whether having a history of incarceration affects response to primary care office-based buprenorphine/naloxone treatment. DESIGN: In this post hoc secondary analysis of a randomized clinical trial, we compared demographic, clinical characteristics, and treatment outcomes among 166 participants receiving primary care office-based buprenorphine/naloxone treatment stratifying on history of incarceration. MAIN RESULTS: Participants with a history of incarceration have similar treatment outcomes with primary care office-based buprenorphine/naloxone than those without a history of incarceration (consecutive weeks of opioid-negative urine samples, 6.2 vs. 5.9, p = 0.43; treatment retention, 38% vs. 46%, p = 0.28). CONCLUSIONS: Prior history of incarceration does not appear to impact primary care office-based treatment of opioid dependence with buprenorphine/naloxone. Community health care providers can be reassured that initiating buprenorphine/naloxone in opioid dependent individuals with a history of incarceration will have similar outcomes as those without this history. BT - Journal of general internal medicine C5 - Healthcare Disparities; Opioids & Substance Use CP - 7 CY - United States DO - 10.1007/s11606-010-1306-0 IS - 7 JF - Journal of general internal medicine N2 - BACKGROUND: Behaviors associated with opioid dependence often involve criminal activity, which can lead to incarceration. The impact of a history of incarceration on outcomes in primary care office-based buprenorphine/naloxone is not known. OBJECTIVE: The purpose of this study is to determine whether having a history of incarceration affects response to primary care office-based buprenorphine/naloxone treatment. DESIGN: In this post hoc secondary analysis of a randomized clinical trial, we compared demographic, clinical characteristics, and treatment outcomes among 166 participants receiving primary care office-based buprenorphine/naloxone treatment stratifying on history of incarceration. MAIN RESULTS: Participants with a history of incarceration have similar treatment outcomes with primary care office-based buprenorphine/naloxone than those without a history of incarceration (consecutive weeks of opioid-negative urine samples, 6.2 vs. 5.9, p = 0.43; treatment retention, 38% vs. 46%, p = 0.28). CONCLUSIONS: Prior history of incarceration does not appear to impact primary care office-based treatment of opioid dependence with buprenorphine/naloxone. Community health care providers can be reassured that initiating buprenorphine/naloxone in opioid dependent individuals with a history of incarceration will have similar outcomes as those without this history. PP - United States PY - 2010 SN - 1525-1497; 0884-8734 SP - 670 EP - 674 EP - T1 - Effect of incarceration history on outcomes of primary care office-based buprenorphine/naloxone T2 - Journal of general internal medicine TI - Effect of incarceration history on outcomes of primary care office-based buprenorphine/naloxone U1 - Healthcare Disparities; Opioids & Substance Use U2 - 20213205 U3 - 10.1007/s11606-010-1306-0 VL - 25 VO - 1525-1497; 0884-8734 Y1 - 2010 ER -