TY - JOUR KW - Adolescent KW - Adult KW - Aged KW - Cognitive Therapy/economics/methods KW - Cost of Illness KW - Cost-Benefit Analysis KW - Depressive Disorder/economics/therapy KW - Health Care Costs/statistics & numerical data KW - Humans KW - Middle Aged KW - Netherlands KW - Primary Health Care/economics/methods KW - Psychiatric Status Rating Scales KW - Quality of Life KW - Sensitivity and Specificity KW - Therapy, Computer-Assisted/economics/methods KW - Treatment Outcome KW - Young Adult AU - S. A. Gerhards AU - L. E. de Graaf AU - L. E. Jacobs AU - J. L. Severens AU - M. J. Huibers AU - A. Arntz AU - H. Riper AU - G. Widdershoven AU - J. F. Metsemakers AU - S. M. Evers A1 - AB - BACKGROUND: Evidence about the cost-effectiveness and cost utility of computerised cognitive-behavioural therapy (CCBT) is still limited. Recently, we compared the clinical effectiveness of unsupported, online CCBT with treatment as usual (TAU) and a combination of CCBT and TAU (CCBT plus TAU) for depression. The study is registered at the Netherlands Trial Register, part of the Dutch Cochrane Centre (ISRCTN47481236). AIMS: To assess the cost-effectiveness of CCBT compared with TAU and CCBT plus TAU. METHOD: Costs, depression severity and quality of life were measured for 12 months. Cost-effectiveness and cost-utility analyses were performed from a societal perspective. Uncertainty was dealt with by bootstrap replications and sensitivity analyses. RESULTS: Costs were lowest for the CCBT group. There are no significant group differences in effectiveness or quality of life. Cost-utility and cost-effectiveness analyses tend to be in favour of CCBT. CONCLUSIONS: On balance, CCBT constitutes the most efficient treatment strategy, although all treatments showed low adherence rates and modest improvements in depression and quality of life. BT - The British journal of psychiatry : the journal of mental science C5 - Financing & Sustainability; HIT & Telehealth CY - England DO - 10.1192/bjp.bp.109.065748 JF - The British journal of psychiatry : the journal of mental science N2 - BACKGROUND: Evidence about the cost-effectiveness and cost utility of computerised cognitive-behavioural therapy (CCBT) is still limited. Recently, we compared the clinical effectiveness of unsupported, online CCBT with treatment as usual (TAU) and a combination of CCBT and TAU (CCBT plus TAU) for depression. The study is registered at the Netherlands Trial Register, part of the Dutch Cochrane Centre (ISRCTN47481236). AIMS: To assess the cost-effectiveness of CCBT compared with TAU and CCBT plus TAU. METHOD: Costs, depression severity and quality of life were measured for 12 months. Cost-effectiveness and cost-utility analyses were performed from a societal perspective. Uncertainty was dealt with by bootstrap replications and sensitivity analyses. RESULTS: Costs were lowest for the CCBT group. There are no significant group differences in effectiveness or quality of life. Cost-utility and cost-effectiveness analyses tend to be in favour of CCBT. CONCLUSIONS: On balance, CCBT constitutes the most efficient treatment strategy, although all treatments showed low adherence rates and modest improvements in depression and quality of life. PP - England PY - 2010 SN - 1472-1465; 0007-1250 SP - 310 EP - 318 EP - T1 - Economic evaluation of online computerised cognitive-behavioural therapy without support for depression in primary care: Randomised trial T2 - The British journal of psychiatry : the journal of mental science TI - Economic evaluation of online computerised cognitive-behavioural therapy without support for depression in primary care: Randomised trial U1 - Financing & Sustainability; HIT & Telehealth U2 - 20357309 U3 - 10.1192/bjp.bp.109.065748 VL - 196 VO - 1472-1465; 0007-1250 Y1 - 2010 ER -