TY - JOUR KW - Adult KW - Anxiety/epidemiology/etiology KW - Comorbidity KW - Depression/epidemiology/etiology KW - Female KW - Humans KW - Male KW - Neuropsychology KW - Pain Measurement KW - Predictive Value of Tests KW - Prevalence KW - Primary Health Care/statistics & numerical data KW - Psychological Tests KW - Psychometrics KW - Questionnaires KW - Risk Factors KW - Somatoform Disorders/complications/epidemiology KW - South Africa/epidemiology AU - J. E. Muller AU - I. Wentzel AU - D. G. Nel AU - D. J. Stein A1 - AB - OBJECTIVE: Multisomatoform disorder (MSD) is characterised by > or = 3 medically inexplicable, troublesome physical symptoms, together with a > or = 2-year history of somatisation. The aim of this study was to evaluate the prevalence of depressive and anxiety disorders in a South African sample MSD, and to compare demographic and clinical outcomes in those patients with and without co-morbidity. METHODS: Fifty-one adult outpatients with MSD were recruited from primary care clinics in the Cape Town metropolitan area. Participants were assessed for the presence of co-morbid depressive and anxiety disorders using the Mini Neuropsychiatric Interview-Plus (MINI-Plus). Outcomes included somatic symptom severity, disability, reported sick days and health care visits, pain experience, patient satisfaction with health services, and clinician-experienced difficulty. RESULTS: A current co-morbid depressive disorder was present in 29.4% (N = 15) of patients, and a current co-morbid anxiety disorder in 52.9% (N = 27). MSD patients with a co-morbid depressive disorder (current or lifetime) had significantly higher physical symptom counts, greater functional impairment, higher unemployment rates, more clinician-reported difficulties, and more dissatisfaction with health care services than those without the disorder. A larger number of co-morbid disorders was associated with greater overall disability. CONCLUSION: High rates of co-morbid depressive and anxiety disorders were present in a South African sample of primary care patients with MSD. Not all patients had co-morbidity, which is consistent with the view that MSD should be viewed as an independent disorder. However, co-morbid depressive disorders were associated with increased symptom severity and functional impairment, consistent with previous reports from developing countries, emphasising the importance of comorbidity in MSD. BT - South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde C5 - Medically Unexplained Symptoms CP - 6 CY - South Africa IS - 6 JF - South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde N2 - OBJECTIVE: Multisomatoform disorder (MSD) is characterised by > or = 3 medically inexplicable, troublesome physical symptoms, together with a > or = 2-year history of somatisation. The aim of this study was to evaluate the prevalence of depressive and anxiety disorders in a South African sample MSD, and to compare demographic and clinical outcomes in those patients with and without co-morbidity. METHODS: Fifty-one adult outpatients with MSD were recruited from primary care clinics in the Cape Town metropolitan area. Participants were assessed for the presence of co-morbid depressive and anxiety disorders using the Mini Neuropsychiatric Interview-Plus (MINI-Plus). Outcomes included somatic symptom severity, disability, reported sick days and health care visits, pain experience, patient satisfaction with health services, and clinician-experienced difficulty. RESULTS: A current co-morbid depressive disorder was present in 29.4% (N = 15) of patients, and a current co-morbid anxiety disorder in 52.9% (N = 27). MSD patients with a co-morbid depressive disorder (current or lifetime) had significantly higher physical symptom counts, greater functional impairment, higher unemployment rates, more clinician-reported difficulties, and more dissatisfaction with health care services than those without the disorder. A larger number of co-morbid disorders was associated with greater overall disability. CONCLUSION: High rates of co-morbid depressive and anxiety disorders were present in a South African sample of primary care patients with MSD. Not all patients had co-morbidity, which is consistent with the view that MSD should be viewed as an independent disorder. However, co-morbid depressive disorders were associated with increased symptom severity and functional impairment, consistent with previous reports from developing countries, emphasising the importance of comorbidity in MSD. PP - South Africa PY - 2008 SN - 0256-9574; 0256-9574 SP - 473 EP - 476 EP - T1 - Depression and anxiety in multisomatoform disorder: prevalence and clinical predictors in primary care T2 - South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde TI - Depression and anxiety in multisomatoform disorder: prevalence and clinical predictors in primary care U1 - Medically Unexplained Symptoms U2 - 18683382 VL - 98 VO - 0256-9574; 0256-9574 Y1 - 2008 ER -