TY - JOUR KW - Adolescent KW - Adult KW - Aged KW - Cognitive Therapy/economics KW - Cost-Benefit Analysis KW - Depressive Disorder/economics/prevention & control KW - Female KW - Health Care Costs KW - Humans KW - Male KW - Middle Aged KW - Primary Health Care/economics AU - F. Smit AU - G. Willemse AU - M. Koopmanschap AU - S. Onrust AU - P. Cuijpers AU - A. Beekman A1 - AB - BACKGROUND: Little is known about the cost-effectiveness of preventing mental disorders. AIMS: To study the cost-effectiveness of care as usual plus minimal contact psychotherapy relative to usual care alone in preventing depressive disorder. METHOD: An economic evaluation was conducted alongside a randomised clinical trial. Primary care patients with sub-threshold depression were assigned to minimal contact psychotherapy plus usual care (n=107) or to usual care alone (n=109). RESULTS: Primary care patients with sub-threshold depression benefited from minimal contact psychotherapy as it reduced the risk of developing a full-blown depressive disorder from 18% to 12%. In addition, this intervention had a 70% probability of being more cost-effective than usual care alone. A sensitivity analysis indicated the robustness of these results. CONCLUSIONS: Over 1 year adjunctive minimal contact psychotherapy improved outcomes and generated lower costs. This intervention is therefore superior to usual care alone in terms of cost-effectiveness. BT - The British journal of psychiatry : the journal of mental science C5 - Financing & Sustainability CY - England DO - 10.1192/bjp.188.4.330 JF - The British journal of psychiatry : the journal of mental science N2 - BACKGROUND: Little is known about the cost-effectiveness of preventing mental disorders. AIMS: To study the cost-effectiveness of care as usual plus minimal contact psychotherapy relative to usual care alone in preventing depressive disorder. METHOD: An economic evaluation was conducted alongside a randomised clinical trial. Primary care patients with sub-threshold depression were assigned to minimal contact psychotherapy plus usual care (n=107) or to usual care alone (n=109). RESULTS: Primary care patients with sub-threshold depression benefited from minimal contact psychotherapy as it reduced the risk of developing a full-blown depressive disorder from 18% to 12%. In addition, this intervention had a 70% probability of being more cost-effective than usual care alone. A sensitivity analysis indicated the robustness of these results. CONCLUSIONS: Over 1 year adjunctive minimal contact psychotherapy improved outcomes and generated lower costs. This intervention is therefore superior to usual care alone in terms of cost-effectiveness. PP - England PY - 2006 SN - 0007-1250; 0007-1250 SP - 330 EP - 336 EP - T1 - Cost-effectiveness of preventing depression in primary care patients: Randomised trial T2 - The British journal of psychiatry : the journal of mental science TI - Cost-effectiveness of preventing depression in primary care patients: Randomised trial U1 - Financing & Sustainability U2 - 16582059 U3 - 10.1192/bjp.188.4.330 VL - 188 VO - 0007-1250; 0007-1250 Y1 - 2006 ER -