TY - JOUR AU - J. M. Braciszewski AU - M. Elmali AU - E. N. Llamocca AU - A. M. Vanderziel AU - H. Cameron-Carter AU - A. M. Loree A1 - AB - Electronic cigarettes (e-cigarettes) are the most used tobacco product among US adolescents. Information about the prevalence of use in a pediatric primary care population has been limited. Youth aged 12 to 17 attending a well-child visit completed screening for past year e-cigarette, cigarette, cannabis, and alcohol use, as well as depression and anxiety symptoms. We examined e-cigarette-use prevalence, frequency, and relationship to demographics, mental health symptoms, and other substance use. Among 9740 patients, 8.2% reported past-year e-cigarette use. Males (7.2%) were less likely than females (9.2%) to use e-cigarettes, while more frequent use was associated with more frequent cannabis, alcohol, and cigarette use, as well as elevated depression and anxiety symptoms. Sex differences support a recent trend toward young females using e-cigarettes at higher rates than males. Polysubstance use was common, highlighting the importance of regular screening for all substances and feasible interventions for this setting. AD - Center for Health Policy and Health Services Research, Henry Ford Health, Detroit, MI, USA.; Wayne State University School of Medicine, Detroit, MI, USA.; Department of Psychiatry, Henry Ford Health, Detroit, MI, USA. AN - 41461569 BT - Clin Pediatr (Phila) C5 - Opioids & Substance Use; Healthcare Disparities CP - 4 DA - 05/2026 DO - 10.1177/00099228251399041 DP - NLM ET - 20251229 IS - 4 JF - Clin Pediatr (Phila) LA - eng N2 - Electronic cigarettes (e-cigarettes) are the most used tobacco product among US adolescents. Information about the prevalence of use in a pediatric primary care population has been limited. Youth aged 12 to 17 attending a well-child visit completed screening for past year e-cigarette, cigarette, cannabis, and alcohol use, as well as depression and anxiety symptoms. We examined e-cigarette-use prevalence, frequency, and relationship to demographics, mental health symptoms, and other substance use. Among 9740 patients, 8.2% reported past-year e-cigarette use. Males (7.2%) were less likely than females (9.2%) to use e-cigarettes, while more frequent use was associated with more frequent cannabis, alcohol, and cigarette use, as well as elevated depression and anxiety symptoms. Sex differences support a recent trend toward young females using e-cigarettes at higher rates than males. Polysubstance use was common, highlighting the importance of regular screening for all substances and feasible interventions for this setting. PY - 2026 SN - 0009-9228 (Print); 0009-9228 SP - 499 EP - 505+ ST - Prevalence and Mental Health Correlates of Electronic Cigarette Use Among Pediatric Primary Care Patients T1 - Prevalence and Mental Health Correlates of Electronic Cigarette Use Among Pediatric Primary Care Patients T2 - Clin Pediatr (Phila) TI - Prevalence and Mental Health Correlates of Electronic Cigarette Use Among Pediatric Primary Care Patients U1 - Opioids & Substance Use; Healthcare Disparities U3 - 10.1177/00099228251399041 VL - 65 VO - 0009-9228 (Print); 0009-9228 Y1 - 2026 ER -