TY - JOUR
AU - E. O. A. Wambiya
AU - D. Gillespie
AU - R. Akparibo
AU - J. O. Oguta
AU - C. Akoth
AU - P. Otieno
AU - P. J. Dodd
A1 - 
AB - INTRODUCTION: Integrated care is increasingly adopted to address the needs of patients with multimorbidity, but cost-effective configuration of integrated healthcare pathways remains unclear. This study reviewed decision analytic models (DAMs) used in economic evaluations of integrated care interventions for cardiometabolic multimorbidity. METHODS: A systematic search of eight electronic databases was conducted to identify peer-reviewed articles published in English until November 2024. Studies using DAMs to evaluate integrated care interventions for patients at risk or having cardiometabolic multimorbidity were included. Data on DAMs characteristics, integrated care models evaluated, and diseases were summarised. The quality of reporting was assessed using Philips (2006) checklist. RESULTS: Sixteen studies met inclusion criteria. Most studies (81%) were cost utility analyses, focused on hypertension and/or diabetes concordant multimorbidity (69%). High-income countries accounted for 69% of the studies. Markov models were used the most (63%), with only three studies employing individual patient simulation (microsimulation) models. Few studies were explicit about data validation and reporting uncertainty. CONCLUSION: Economic evaluations of integrated care cardiometabolic multimorbidity should adopt microsimulation to better capture patient-level interactions and health outcomes. Better reporting of validation and uncertainty is needed. There is limited application of DAM-based economic evaluations of integrated care in low- and middle-income countries.
AD - Sheffield Centre for Health and Related Research (SCHARR), School of Medicine and Population Health, University of Sheffield, Sheffield, United Kingdom.; Chronic disease management (CDM) unit, African Population and Health Research Center (APHRC), Nairobi, Kenya.
AN - 42078861
BT - Int J Integr Care
C5 - Financing & Sustainability
CP - 2
DA - 12/1969
DO - 10.5334/ijic.9075
DP - NLM
ET - 20260427
IS - 2
JF - Int J Integr Care
LA - eng
N2 - INTRODUCTION: Integrated care is increasingly adopted to address the needs of patients with multimorbidity, but cost-effective configuration of integrated healthcare pathways remains unclear. This study reviewed decision analytic models (DAMs) used in economic evaluations of integrated care interventions for cardiometabolic multimorbidity. METHODS: A systematic search of eight electronic databases was conducted to identify peer-reviewed articles published in English until November 2024. Studies using DAMs to evaluate integrated care interventions for patients at risk or having cardiometabolic multimorbidity were included. Data on DAMs characteristics, integrated care models evaluated, and diseases were summarised. The quality of reporting was assessed using Philips (2006) checklist. RESULTS: Sixteen studies met inclusion criteria. Most studies (81%) were cost utility analyses, focused on hypertension and/or diabetes concordant multimorbidity (69%). High-income countries accounted for 69% of the studies. Markov models were used the most (63%), with only three studies employing individual patient simulation (microsimulation) models. Few studies were explicit about data validation and reporting uncertainty. CONCLUSION: Economic evaluations of integrated care cardiometabolic multimorbidity should adopt microsimulation to better capture patient-level interactions and health outcomes. Better reporting of validation and uncertainty is needed. There is limited application of DAM-based economic evaluations of integrated care in low- and middle-income countries.
PY - 2026
SN - 1568-4156 (Print)
SP - 7
ST - Application of Decision-Analytic Models to Evaluate Integrated Care Interventions for Cardiometabolic Multimorbidity: A Systematic Review
T1 - Application of Decision-Analytic Models to Evaluate Integrated Care Interventions for Cardiometabolic Multimorbidity: A Systematic Review
T2 - Int J Integr Care
TI - Application of Decision-Analytic Models to Evaluate Integrated Care Interventions for Cardiometabolic Multimorbidity: A Systematic Review
U1 - Financing & Sustainability
U3 - 10.5334/ijic.9075
VL - 26
VO - 1568-4156 (Print)
Y1 - 2026
ER -