TY - JOUR
AU - H. Shui
AU - X. Cao
AU - X. Zhang
A1 - 
AB - Perinatal depression (PND), encompassing both major and minor depressive episodes during pregnancy and up to one year postpartum, is a prevalent and debilitating condition with profound consequences for maternal, infant, and family well-being. Clinical screening of PND remains challenging due to obstacles in early detection, symptom overlap with normal perinatal experiences, lack of standardized screening protocols, and considerable interpatient variability. Furthermore, the complexity of treating PND arises from multiple interconnected factors, including medication safety considerations during pregnancy and lactation, information barriers resulting from the separation of mental health services from obstetric and pediatric care systems, and unique sociocultural obstacles. The absence of systematically integrated care pathways often leads to severe and potentially irreversible outcomes for both mothers and infants. Hence, this review summarizes recent advances in PND screening and treatment, emphasizing the critical transition toward integrated or collaborative care models. Notably, future efforts should focus on overcoming implementation barriers, digital health solutions, task-sharing frameworks, and personalized treatment strategies to ensure equitable access to these innovations for affected populations.
AD - Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
AN - 42355633
BT - J Clin Med
C5 - Healthcare Disparities
CP - 12
DA - 06/2026
DO - 10.3390/jcm15124465
DP - NLM
ET - 20260609
IS - 12
JF - J Clin Med
LA - eng
N2 - Perinatal depression (PND), encompassing both major and minor depressive episodes during pregnancy and up to one year postpartum, is a prevalent and debilitating condition with profound consequences for maternal, infant, and family well-being. Clinical screening of PND remains challenging due to obstacles in early detection, symptom overlap with normal perinatal experiences, lack of standardized screening protocols, and considerable interpatient variability. Furthermore, the complexity of treating PND arises from multiple interconnected factors, including medication safety considerations during pregnancy and lactation, information barriers resulting from the separation of mental health services from obstetric and pediatric care systems, and unique sociocultural obstacles. The absence of systematically integrated care pathways often leads to severe and potentially irreversible outcomes for both mothers and infants. Hence, this review summarizes recent advances in PND screening and treatment, emphasizing the critical transition toward integrated or collaborative care models. Notably, future efforts should focus on overcoming implementation barriers, digital health solutions, task-sharing frameworks, and personalized treatment strategies to ensure equitable access to these innovations for affected populations.
PY - 2026
SN - 2077-0383 (Print); 2077-0383
ST - Advances in Perinatal Depression: A Focus on Screening and Treatment
T1 - Advances in Perinatal Depression: A Focus on Screening and Treatment
T2 - J Clin Med
TI - Advances in Perinatal Depression: A Focus on Screening and Treatment
U1 - Healthcare Disparities
U3 - 10.3390/jcm15124465
VL - 15
VO - 2077-0383 (Print); 2077-0383
Y1 - 2026
ER -