TY - JOUR AU - D . Y. Johnson AU - E. M. Staab AU - P. Hahn AU - C. Lusk AU - E. K. Zahradnik AU - N. Laiteerapong A1 - AB - OBJECTIVE: The Collaborative Care Model, which integrates primary care, behavioral health, and structured care management, is a promising approach to improving outcomes for patients with cognitive impairment and neuropsychiatric symptoms. This study evaluated a pilot of Cognitive Impairment Collaborative Care (CICC) at a large urban academic medical center. METHOD: Retrospective chart review of adults enrolled in the first year of the program (November 1, 2021 to October 31, 2022). CICC included assessments, biweekly telehealth visits, care management, psychiatric consultation, and therapy. The primary outcome was clinical effectiveness, defined as the change in Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7) scores. Secondary outcomes were adoption (number of clinicians referring), reach (patient enrollment), and implementation (number of encounters and psychiatric case reviews). RESULTS: Twenty-two patients enrolled in CICC; all had depression or anxiety. About 5% of primary care clinicians referred an average of 1.6 patients (SD 1.7) in the first year. On average, patients were enrolled for 144.9 days (SD 79.7), had 2.3 encounters per month (SD 1.0), were case reviewed 8.6 times (SD 5.3), and 50% graduated in the first year. Patients exhibited significant reductions in depression (PHQ-9: mean change -4.7, SD 5.0, p = 0.003) and anxiety scores (GAD-7: mean change -4.3, SD 5.5, p = 0.01). CONCLUSIONS: CICC achieved modest adoption and reach with demonstrated effectiveness in reducing depression and anxiety among patients with cognitive impairment. RELEVANCE TO CLINICAL PRACTICE: Amid a shortage of geriatricians and geriatric psychiatrists in the U.S., collaborative care is a possible therapeutic option for the growing geriatric population. AD - Pritzker School of Medicine University of Chicago Chicago Illinois USA.; Department of Medicine University of Chicago Chicago Illinois USA.; Department of Psychiatry and Behavioral Neuroscience University of Chicago Chicago Illinois USA. AN - 42500272 BT - Psychiatr Res Clin Pract C5 - Healthcare Disparities; Education & Workforce; HIT & Telehealth DA - 06/2026 DO - 10.1176/appi.prcp.20240109 DP - NLM ET - 20260616 JF - Psychiatr Res Clin Pract LA - eng N2 - OBJECTIVE: The Collaborative Care Model, which integrates primary care, behavioral health, and structured care management, is a promising approach to improving outcomes for patients with cognitive impairment and neuropsychiatric symptoms. This study evaluated a pilot of Cognitive Impairment Collaborative Care (CICC) at a large urban academic medical center. METHOD: Retrospective chart review of adults enrolled in the first year of the program (November 1, 2021 to October 31, 2022). CICC included assessments, biweekly telehealth visits, care management, psychiatric consultation, and therapy. The primary outcome was clinical effectiveness, defined as the change in Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7) scores. Secondary outcomes were adoption (number of clinicians referring), reach (patient enrollment), and implementation (number of encounters and psychiatric case reviews). RESULTS: Twenty-two patients enrolled in CICC; all had depression or anxiety. About 5% of primary care clinicians referred an average of 1.6 patients (SD 1.7) in the first year. On average, patients were enrolled for 144.9 days (SD 79.7), had 2.3 encounters per month (SD 1.0), were case reviewed 8.6 times (SD 5.3), and 50% graduated in the first year. Patients exhibited significant reductions in depression (PHQ-9: mean change -4.7, SD 5.0, p = 0.003) and anxiety scores (GAD-7: mean change -4.3, SD 5.5, p = 0.01). CONCLUSIONS: CICC achieved modest adoption and reach with demonstrated effectiveness in reducing depression and anxiety among patients with cognitive impairment. RELEVANCE TO CLINICAL PRACTICE: Amid a shortage of geriatricians and geriatric psychiatrists in the U.S., collaborative care is a possible therapeutic option for the growing geriatric population. PY - 2026 SN - 2575-5609 ST - A Real-World Pilot of the Collaborative Care Model for Adults With Cognitive Impairment and Neuropsychiatric Symptoms in Primary Care T1 - A Real-World Pilot of the Collaborative Care Model for Adults With Cognitive Impairment and Neuropsychiatric Symptoms in Primary Care T2 - Psychiatr Res Clin Pract TI - A Real-World Pilot of the Collaborative Care Model for Adults With Cognitive Impairment and Neuropsychiatric Symptoms in Primary Care U1 - Healthcare Disparities; Education & Workforce; HIT & Telehealth U3 - 10.1176/appi.prcp.20240109 VO - 2575-5609 Y1 - 2026 ER -