TY - JOUR AU - D. R. Hijano A1 - AB - This conceptual policy analysis examines the persistent gap between population health frameworks and their implementation in practice, using pediatric immunizations as a case example. Declining vaccine coverage and widening geographic disparities illustrate how broad definitions of population health may lack the operational structure needed to guide coordinated governance and delivery. Informed by a structured narrative review of peer-reviewed literature, policy reports, and national surveillance data, the Rainbow Model of Integrated Care is applied to analyze how clinical, professional, organizational, system, functional, and normative domains shape immunization performance across preventive care systems. The analysis identifies policy-relevant levers, including interoperable data infrastructure, alignment of exemption governance, integration of equity-focused payment incentives, community-partnered outreach, and transparent performance monitoring. For each domain, implementation considerations, authority structures, privacy safeguards, resourcing implications, and potential political and ethical trade-offs are examined. Illustrative measurable indicators are proposed to operationalize integration and support accountability. Although grounded primarily in the United States context, the challenges described and structural considerations discussed are relevant to other decentralized health systems. This analysis suggests that structured integration frameworks may assist policymakers in translating population health principles into coordinated and ethically grounded implementation strategies for immunization systems. AD - Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, United States.; Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, United States. AN - 41929893 BT - Front Public Health C5 - Healthcare Disparities DO - 10.3389/fpubh.2026.1749357 DP - NLM ET - 20260318 JF - Front Public Health LA - eng N2 - This conceptual policy analysis examines the persistent gap between population health frameworks and their implementation in practice, using pediatric immunizations as a case example. Declining vaccine coverage and widening geographic disparities illustrate how broad definitions of population health may lack the operational structure needed to guide coordinated governance and delivery. Informed by a structured narrative review of peer-reviewed literature, policy reports, and national surveillance data, the Rainbow Model of Integrated Care is applied to analyze how clinical, professional, organizational, system, functional, and normative domains shape immunization performance across preventive care systems. The analysis identifies policy-relevant levers, including interoperable data infrastructure, alignment of exemption governance, integration of equity-focused payment incentives, community-partnered outreach, and transparent performance monitoring. For each domain, implementation considerations, authority structures, privacy safeguards, resourcing implications, and potential political and ethical trade-offs are examined. Illustrative measurable indicators are proposed to operationalize integration and support accountability. Although grounded primarily in the United States context, the challenges described and structural considerations discussed are relevant to other decentralized health systems. This analysis suggests that structured integration frameworks may assist policymakers in translating population health principles into coordinated and ethically grounded implementation strategies for immunization systems. PY - 2026 SN - 2296-2565 SP - 1749357 ST - Rethinking population health in practice: pediatric immunizations as a policy and system integration case T1 - Rethinking population health in practice: pediatric immunizations as a policy and system integration case T2 - Front Public Health TI - Rethinking population health in practice: pediatric immunizations as a policy and system integration case U1 - Healthcare Disparities U3 - 10.3389/fpubh.2026.1749357 VL - 14 VO - 2296-2565 Y1 - 2026 ER -