TY - JOUR
AU - E. Ahounbar
AU - A. A. Guerin
AU - L. Hides
AU - S. Bendall
AU - A. Chanen
AU - S. Clarke
AU - A. Quinn
AU - S. Baird
AU - E. Killackey
AU - P. McGorry
AU - G. Bedi
A1 - 
AB - AIMS: Both substance use and mental illness commonly onset during adolescence or young adulthood, and rates of substance use in young people with mental illness are disproportionately high. This baseline data paper from a clinical trial testing an integrated early intervention for substance use and mental health problems aims to (1) describe the characteristics of participants enrolled and (2) compare young people with a current and without a lifetime diagnosis of substance use disorder (SUD) in terms of psychiatric symptoms, functioning, and substance use. METHODS: Seventy-nine participants aged 12-25 years with high prevalence mental illness (e.g., depression, anxiety) and substance use seeking mental healthcare were recruited from headspace primary mental health centres in North-Western Melbourne. At baseline, they completed self-report and interview measures of psychiatric diagnoses and symptoms, functioning, and substance use. We compared those with a current (n = 51) and without a lifetime (n = 21) SUD on these measures. This is a secondary data analysis of baseline data for the INTEGRATE clinical trial. RESULTS: Youth with an SUD endorsed more severe depressive and anxiety symptoms, and lower quality of life and role functioning than those who used substances without a lifetime SUD. They also had more alcohol-related problems and higher frequency cannabis use and higher risk scores for alcohol, tobacco, cannabis, cocaine, amphetamine-type stimulants and hallucinogen use. There were no group differences in social and occupational functioning or subjectively rated sleep quality. CONCLUSIONS: Findings highlight the need for early identification and integrated care models within youth mental health services to address the high prevalence and impact of substance use, potentially reducing adverse effects of co-occurring SUD and mental illness on youth development and functioning. TRIAL REGISTRATION: The study was preregistered (ACTRN12619001522101).
AD - Centre for Youth Mental Health, University of Melbourne and Orygen, Melbourne, Australia.; School of Psychology, University of Queensland, Brisbane, Australia.; National Centre for Youth Substance Use Research, University of Queensland, Brisbane, Australia.; School of Population and Global Health, University of Western Australia, Perth, Australia.
AN - 41320196
BT - Early Interv Psychiatry
C5 - Healthcare Disparities; Opioids & Substance Use
CP - 12
DA - Dec
DO - 10.1111/eip.70106
DP - NLM
IS - 12
JF - Early Interv Psychiatry
LA - eng
N2 - AIMS: Both substance use and mental illness commonly onset during adolescence or young adulthood, and rates of substance use in young people with mental illness are disproportionately high. This baseline data paper from a clinical trial testing an integrated early intervention for substance use and mental health problems aims to (1) describe the characteristics of participants enrolled and (2) compare young people with a current and without a lifetime diagnosis of substance use disorder (SUD) in terms of psychiatric symptoms, functioning, and substance use. METHODS: Seventy-nine participants aged 12-25 years with high prevalence mental illness (e.g., depression, anxiety) and substance use seeking mental healthcare were recruited from headspace primary mental health centres in North-Western Melbourne. At baseline, they completed self-report and interview measures of psychiatric diagnoses and symptoms, functioning, and substance use. We compared those with a current (n = 51) and without a lifetime (n = 21) SUD on these measures. This is a secondary data analysis of baseline data for the INTEGRATE clinical trial. RESULTS: Youth with an SUD endorsed more severe depressive and anxiety symptoms, and lower quality of life and role functioning than those who used substances without a lifetime SUD. They also had more alcohol-related problems and higher frequency cannabis use and higher risk scores for alcohol, tobacco, cannabis, cocaine, amphetamine-type stimulants and hallucinogen use. There were no group differences in social and occupational functioning or subjectively rated sleep quality. CONCLUSIONS: Findings highlight the need for early identification and integrated care models within youth mental health services to address the high prevalence and impact of substance use, potentially reducing adverse effects of co-occurring SUD and mental illness on youth development and functioning. TRIAL REGISTRATION: The study was preregistered (ACTRN12619001522101).
PY - 2025
SN - 1751-7885
SP - e70106
ST - Characteristics of Youth With Recent Substance Use With and Without Substance Use Disorder Presenting for Primary Mental Healthcare in Australia: Baseline Findings From the INTEGRATE Trial
T1 - Characteristics of Youth With Recent Substance Use With and Without Substance Use Disorder Presenting for Primary Mental Healthcare in Australia: Baseline Findings From the INTEGRATE Trial
T2 - Early Interv Psychiatry
TI - Characteristics of Youth With Recent Substance Use With and Without Substance Use Disorder Presenting for Primary Mental Healthcare in Australia: Baseline Findings From the INTEGRATE Trial
U1 - Healthcare Disparities; Opioids & Substance Use
U3 - 10.1111/eip.70106
VL - 19
VO - 1751-7885
Y1 - 2025
ER -