TY - JOUR AU - I. M. Nasrallah AU - C. Polacek AU - F. H. Frech AU - P. N. Tariot AU - J. Vawter AU - Y. Zabar AU - C. Divers AU - W . Y. Shang AU - D. S. Geldmacher AU - M. Towman AU - H. Reiter AU - C. D. Marshall AU - V. Baldivieso AU - D. R. Jones AU - E. S. Musiek AU - H. Toyosaki AU - B. Tousi A1 - AB - Alzheimer's disease (AD) is often underdiagnosed, especially at early stages when symptoms are mild, and patients may benefit from new and recently approved anti-amyloid therapies. An updated patient care pathway may facilitate timely diagnosis and intervention. We conducted a scan of published information and convened an expert panel of health care professionals to gain insights on early AD care pathways. We developed an Early AD Patient Care Pathway as an implementation guide that includes new diagnostic and treatment modalities and addresses needs and opportunities. The Early AD Patient Care Pathway focuses on patient identification, assessment, diagnosis, treatment, and management and monitoring. Operational readiness considerations aid pathway implementation and include evaluating and addressing gaps in program and business planning, technology, education and resources, access and reimbursement, and care coordination. The pathway is adaptable to health system needs and may be further tested and refined for sustainability. HIGHLIGHTS: We analyzed published information and insights from subject matter experts on care pathways for early Alzheimer's disease.We identified opportunities to improve screening of at-risk patients, make appropriate specialist referrals, and ensure timely access and care coordination for diagnosis, treatment, and monitoring as a means of incorporating the latest diagnostics and therapy options.We developed a care pathway that promotes an integrated approach to patient care and is adaptable to various healthcare settings with input from subject matter experts. AD - Department of Radiology University of Pennsylvania Hospital Philadelphia Pennsylvania USA.; Applied Sciences Premier Inc. Charlotte North Carolina USA.; US Neurology Medical Affairs Eisai Inc. Nutley New Jersey USA.; Banner Alzheimer's Institute University of Arizona College of Medicine Phoenix Arizona USA.; Global Medical Affairs Biogen Inc. Cambridge Massachusetts USA.; Department of Geriatrics Norton Healthcare Louisville Kentucky USA.; Callahan Eye Hospital University of Alabama at Birmingham Birmingham Alabama USA.; AT&T Memory Center Baylor Scott & White Health Dallas Texas USA.; Medical Group Memory Care at Innovation Tower AdventHealth Orlando Florida USA.; Department of Neurology Washington University St. Louis Missouri USA.; Lou Ruvo Center for Brain Health Cleveland Clinic Cleveland Ohio USA. AN - 41189641 BT - Alzheimers Dement (N Y) C5 - Healthcare Disparities CP - 4 DA - Oct-Dec DO - 10.1002/trc2.70162 DP - NLM ET - 20251103 IS - 4 JF - Alzheimers Dement (N Y) LA - eng N2 - Alzheimer's disease (AD) is often underdiagnosed, especially at early stages when symptoms are mild, and patients may benefit from new and recently approved anti-amyloid therapies. An updated patient care pathway may facilitate timely diagnosis and intervention. We conducted a scan of published information and convened an expert panel of health care professionals to gain insights on early AD care pathways. We developed an Early AD Patient Care Pathway as an implementation guide that includes new diagnostic and treatment modalities and addresses needs and opportunities. The Early AD Patient Care Pathway focuses on patient identification, assessment, diagnosis, treatment, and management and monitoring. Operational readiness considerations aid pathway implementation and include evaluating and addressing gaps in program and business planning, technology, education and resources, access and reimbursement, and care coordination. The pathway is adaptable to health system needs and may be further tested and refined for sustainability. HIGHLIGHTS: We analyzed published information and insights from subject matter experts on care pathways for early Alzheimer's disease.We identified opportunities to improve screening of at-risk patients, make appropriate specialist referrals, and ensure timely access and care coordination for diagnosis, treatment, and monitoring as a means of incorporating the latest diagnostics and therapy options.We developed a care pathway that promotes an integrated approach to patient care and is adaptable to various healthcare settings with input from subject matter experts. PY - 2025 SN - 2352-8737 SP - e70162 ST - Early Alzheimer's disease patient care pathway and health system readiness: A framework for integrated care T1 - Early Alzheimer's disease patient care pathway and health system readiness: A framework for integrated care T2 - Alzheimers Dement (N Y) TI - Early Alzheimer's disease patient care pathway and health system readiness: A framework for integrated care U1 - Healthcare Disparities U3 - 10.1002/trc2.70162 VL - 11 VO - 2352-8737 Y1 - 2025 ER -