TY - JOUR AU - A. Evans AU - J. VanWyk AU - M. Kerr AU - A. Couper AU - W. D. Pace AU - Y. Tarabichi AU - R. Pullen AU - M. Pollack AU - M. B. Drummond AU - J. Ohar AU - C. Meldrum AU - M. K. Han AU - A. Kaplan AU - T. Winders AU - J. Wisnivesky AU - B. Make AU - A. Federman AU - V. Carter AU - K. Lang AU - D. Mapel AU - N. A. Hanania AU - D. Stolz AU - F. J. Martinez AU - D. Price A1 - AB - BACKGROUND: Quality improvement programmes (QIPs) are designed to enhance patient outcomes by systematically introducing evidence-based clinical practices. The CONQUEST QIP focuses on improving the identification and management of patients with COPD in primary care. The process of developing CONQUEST, recruiting, preparing systems for participation, and implementing the QIP across three integrated healthcare systems (IHSs) is examined to identify and share lessons learned. APPROACH AND DEVELOPMENT: This review is organized into three stages: 1) development, 2) preparing IHSs for implementation, and 3) implementation. In each stage, key steps are described with the lessons learned and how they can inform others interested in developing QIPs designed to improve the care of patients with chronic conditions in primary care.Stage 1 was establishing and working with steering committees to develop the QIP Quality Standards, define the target patient population, assess current management practices, and create a global operational protocol. Additionally, potential IHSs were assessed for feasibility of QIP integration into primary care practices. Factors assessed included a review of technological infrastructure, QI experience, and capacity for effective implementation.Stage 2 was preparation for implementation. Key was enlisting clinical champions to advocate for the QIP, secure participation in primary care, and establish effective communication channels. Preparation for implementation required obtaining IHS approvals, ensuring Health Insurance Portability and Accountability Act compliance, and devising operational strategies for patient outreach and clinical decision support delivery.Stage 3 was developing three IHS implementation models. With insight into the local context from local clinicians, implementation models were adapted to work with the resources and capacity of the IHSs while ensuring the delivery of essential elements of the programme. CONCLUSION: Developing and launching a QIP programme across primary care practices requires extensive groundwork, preparation, and committed local champions to assist in building an adaptable environment that encourages open communication and is receptive to feedback. AD - Observational and Pragmatic Research Institute Pte Ltd, Singapore, Singapore.; Department of Family Medicine, University of Colorado School of Medicine, Aurora, CO, USA.; Optimum Patient Care Global, Cambridge, UK.; DARTNet Institute, Aurora, CO, USA.; University of Colorado, Denver, CO, USA.; Pulmonologist at Metro Health Medical Center, Cleveland, OH, USA.; BioPharmaceuticals Medical, AstraZeneca, Wilmington, DE, USA.; Division of Pulmonary Diseases and Critical Care Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Internal Medicine, Wake Forest University, Winston-Salem, NC, USA.; Pulmonary and Critical Care Medicine Division, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI, USA.; University of Michigan, Ann Arbor, MI, USA.; Family Physician Airways Group of Canada, Stouffville, ON, Canada.; University of Toronto, Toronto, Canada.; Global Allergy & Airways Patient Platform, Vienna, Austria.; Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Medicine, National Jewish Health, Denver, CO, USA.; Division of General Internal Medicine, Icahn School of Medicine, New York, NY, USA.; University of New Mexico College of Pharmacy, Albuquerque, NM, USA.; Section of Pulmonary and Critical Care Medicine, and Director of the Airways Clinical Research Center, Baylor College of Medicine, Houston, TX, USA.; Clinic of Respiratory Medicine and Faculty of Medicine, University of Freiburg, Freiburg, Germany.; University of Massachusetts Chan Medical School/UMassMemorial Health, Worcester, MA, USA.; Centre of Academic Primary Care, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, UK. AN - 40546134 BT - Prim Health Care Res Dev C5 - Education & Workforce DA - Jun 23 DO - 10.1017/s1463423625100170 DP - NLM ET - 20250623 JF - Prim Health Care Res Dev LA - eng N2 - BACKGROUND: Quality improvement programmes (QIPs) are designed to enhance patient outcomes by systematically introducing evidence-based clinical practices. The CONQUEST QIP focuses on improving the identification and management of patients with COPD in primary care. The process of developing CONQUEST, recruiting, preparing systems for participation, and implementing the QIP across three integrated healthcare systems (IHSs) is examined to identify and share lessons learned. APPROACH AND DEVELOPMENT: This review is organized into three stages: 1) development, 2) preparing IHSs for implementation, and 3) implementation. In each stage, key steps are described with the lessons learned and how they can inform others interested in developing QIPs designed to improve the care of patients with chronic conditions in primary care.Stage 1 was establishing and working with steering committees to develop the QIP Quality Standards, define the target patient population, assess current management practices, and create a global operational protocol. Additionally, potential IHSs were assessed for feasibility of QIP integration into primary care practices. Factors assessed included a review of technological infrastructure, QI experience, and capacity for effective implementation.Stage 2 was preparation for implementation. Key was enlisting clinical champions to advocate for the QIP, secure participation in primary care, and establish effective communication channels. Preparation for implementation required obtaining IHS approvals, ensuring Health Insurance Portability and Accountability Act compliance, and devising operational strategies for patient outreach and clinical decision support delivery.Stage 3 was developing three IHS implementation models. With insight into the local context from local clinicians, implementation models were adapted to work with the resources and capacity of the IHSs while ensuring the delivery of essential elements of the programme. CONCLUSION: Developing and launching a QIP programme across primary care practices requires extensive groundwork, preparation, and committed local champions to assist in building an adaptable environment that encourages open communication and is receptive to feedback. PY - 2025 SN - 1463-4236 (Print); 1463-4236 SP - e50 ST - Practical strategies for achieving system change in the US: lessons and insights from the CONQUEST quality improvement programme T1 - Practical strategies for achieving system change in the US: lessons and insights from the CONQUEST quality improvement programme T2 - Prim Health Care Res Dev TI - Practical strategies for achieving system change in the US: lessons and insights from the CONQUEST quality improvement programme U1 - Education & Workforce U3 - 10.1017/s1463423625100170 VL - 26 VO - 1463-4236 (Print); 1463-4236 Y1 - 2025 ER -