TY - JOUR AU - T. I. Lovejoy AU - T . Y. Wu AU - P. Maloy AU - S. M. McPherson AU - C. L. Smith AU - B. Zaccari A1 - AB - PURPOSE: Little is known about the use of collaborative care models for patients with co-occurring chronic pain and substance use disorders (SUD). This study aimed to pilot test a collaborative care intervention delivered over telehealth to rural patients engaged with SUD treatment who experienced chronic pain. DESIGN: Single-arm, open-label pilot intervention trial. METHODS: Patients (N=88) were enrolled in SUD treatment at a single VA Medical Center and endorsed moderate-to-severe chronic pain. Patients received a nurse-led collaborative care intervention consisting of a comprehensive pain assessment, up to six follow-up appointments with the nurse care manager (NCM), and an optional 10-session pain education class. All patient encounters occurred remotely via telehealth. Baseline, 1- and 4-month follow up assessments measured outcomes of pain, depression, and substance use. Generalized estimating equations and intent-to-treat procedures modelled changes in outcomes over time. RESULTS: Patients were predominantly male (85%) and white (85%), with high mental health and substance use disorder comorbidities (92%). The most common substances of use at treatment initiation were alcohol (49%), opioids (17%), cannabis (17%), methamphetamine (11%), and cocaine (6%). By 4-month follow-up, patients who received the pain intervention endorsed significant reductions in pain intensity, pain interference, and depressive symptoms. Among patients using alcohol or cannabis at baseline, significant reductions in days using these substances were also observed. CONCLUSIONS AND CLINICAL IMPLICATIONS: An NCM-led collaborative care intervention delivered via telehealth may improve both pain and substance use outcomes for rural patients with these comorbidities. Large-scale clinical trials are needed to demonstrate intervention efficacy. AD - VHA Office of Rural Health, Veterans Rural Health Resource Center, Portland, OR; Department of Psychiatry, Oregon Health & Science University, Portland, OR; Center to Improve Veteran Involvement in Care, VA Portland Health Care System, Portland, OR. Electronic address: travis.lovejoy@va.gov.; Department of Psychiatry, Oregon Health & Science University, Portland, OR; Center to Improve Veteran Involvement in Care, VA Portland Health Care System, Portland, OR.; Center to Improve Veteran Involvement in Care, VA Portland Health Care System, Portland, OR.; Elson S. Floyd College of Medicine, Washington State University, Spokane, WA. AN - 39890565 BT - Pain Manag Nurs C5 - Healthcare Disparities; HIT & Telehealth; Opioids & Substance Use CP - 3 DA - Jun DO - 10.1016/j.pmn.2024.12.020 DP - NLM ET - 20250130 IS - 3 JF - Pain Manag Nurs LA - eng N2 - PURPOSE: Little is known about the use of collaborative care models for patients with co-occurring chronic pain and substance use disorders (SUD). This study aimed to pilot test a collaborative care intervention delivered over telehealth to rural patients engaged with SUD treatment who experienced chronic pain. DESIGN: Single-arm, open-label pilot intervention trial. METHODS: Patients (N=88) were enrolled in SUD treatment at a single VA Medical Center and endorsed moderate-to-severe chronic pain. Patients received a nurse-led collaborative care intervention consisting of a comprehensive pain assessment, up to six follow-up appointments with the nurse care manager (NCM), and an optional 10-session pain education class. All patient encounters occurred remotely via telehealth. Baseline, 1- and 4-month follow up assessments measured outcomes of pain, depression, and substance use. Generalized estimating equations and intent-to-treat procedures modelled changes in outcomes over time. RESULTS: Patients were predominantly male (85%) and white (85%), with high mental health and substance use disorder comorbidities (92%). The most common substances of use at treatment initiation were alcohol (49%), opioids (17%), cannabis (17%), methamphetamine (11%), and cocaine (6%). By 4-month follow-up, patients who received the pain intervention endorsed significant reductions in pain intensity, pain interference, and depressive symptoms. Among patients using alcohol or cannabis at baseline, significant reductions in days using these substances were also observed. CONCLUSIONS AND CLINICAL IMPLICATIONS: An NCM-led collaborative care intervention delivered via telehealth may improve both pain and substance use outcomes for rural patients with these comorbidities. Large-scale clinical trials are needed to demonstrate intervention efficacy. PY - 2025 SN - 1524-9042 SP - 264 EP - 270+ ST - Collaborative Tele-Pain and Substance Use Disorder Care for Patients in a Rural Setting: Results of a Single-Arm Open-Label Pilot Trial T1 - Collaborative Tele-Pain and Substance Use Disorder Care for Patients in a Rural Setting: Results of a Single-Arm Open-Label Pilot Trial T2 - Pain Manag Nurs TI - Collaborative Tele-Pain and Substance Use Disorder Care for Patients in a Rural Setting: Results of a Single-Arm Open-Label Pilot Trial U1 - Healthcare Disparities; HIT & Telehealth; Opioids & Substance Use U3 - 10.1016/j.pmn.2024.12.020 VL - 26 VO - 1524-9042 Y1 - 2025 ER -