TY - JOUR
AU - G. K. Mbizvo
AU - I. E. Buchan
AU - A. G. Marson
AU - G. Y. H. Lip
A1 - 
AB - In this concept paper, we introduce epilepsy-heart syndrome as a shared burden of illness between epilepsy and cardiac disorders. This pragmatic definition is agnostic of which condition came first (the epilepsy or the cardiac disorder), recognising that these conditions can each serve as a risk factor for the other owing to a bidirectional relationship that exists between the brain and the heart. To provide clinical context, we include ictal asystole as an example phenotype of epilepsy-heart syndrome. We highlight evidence of patients with ictal asystole coming to harm owing to the failure of integrated care between neurology and cardiology. This underscores epilepsy-heart syndrome as an unmet need for collaborative care between neurology and cardiology. To address this, we propose a framework for integrated care, drawing upon our own centre's recently established and successful multidisciplinary team meeting (MDT) between neurologists and cardiologists, our joint cardiology-neurology PhD programme, and our work developing a joint national guideline on ictal asystole management between the Association of British Neurologists (ABN) and the British Heart Rhythm Society (BHRS).
AD - Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, UK.; Pharmacology and Therapeutics, Institute of Systems, Molecular, and Integrative Biology, University of Liverpool, Liverpool, UK.; Walton Centre National Health Service (NHS) Foundation Trust, Liverpool, UK.; Department of Public Health, Policy, and Systems, Institute of Population Health, University of Liverpool, Liverpool, UK.; Danish Center for Health Services Research, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
AN - 40079478
BT - Epilepsia
C5 - Healthcare Disparities
CP - 6
DA - Jun
DO - 10.1111/epi.18356
DP - NLM
ET - 20250313
IS - 6
JF - Epilepsia
LA - eng
N2 - In this concept paper, we introduce epilepsy-heart syndrome as a shared burden of illness between epilepsy and cardiac disorders. This pragmatic definition is agnostic of which condition came first (the epilepsy or the cardiac disorder), recognising that these conditions can each serve as a risk factor for the other owing to a bidirectional relationship that exists between the brain and the heart. To provide clinical context, we include ictal asystole as an example phenotype of epilepsy-heart syndrome. We highlight evidence of patients with ictal asystole coming to harm owing to the failure of integrated care between neurology and cardiology. This underscores epilepsy-heart syndrome as an unmet need for collaborative care between neurology and cardiology. To address this, we propose a framework for integrated care, drawing upon our own centre's recently established and successful multidisciplinary team meeting (MDT) between neurologists and cardiologists, our joint cardiology-neurology PhD programme, and our work developing a joint national guideline on ictal asystole management between the Association of British Neurologists (ABN) and the British Heart Rhythm Society (BHRS).
PY - 2025
SN - 0013-9580 (Print); 0013-9580
SP - 1830
EP - 1837+
ST - Epilepsy-heart syndrome: Concept, clinical context, and opportunity for integrated care
T1 - Epilepsy-heart syndrome: Concept, clinical context, and opportunity for integrated care
T2 - Epilepsia
TI - Epilepsy-heart syndrome: Concept, clinical context, and opportunity for integrated care
U1 - Healthcare Disparities
U3 - 10.1111/epi.18356
VL - 66
VO - 0013-9580 (Print); 0013-9580
Y1 - 2025
ER -