TY - JOUR AU - M. Changaris A1 - AB - INTRODUCTION: Older adults face significant health risks owing to gaps in the management of polypharmacy and medication adherence, as well as the integration of physical and mental health needs. Current models do not fully address these challenges. This study introduced the Safety, Efficacy, and Adherence (SEA) model designed to enhance interdisciplinary collaboration, improve medication management, and integrate care for older adults. This model addresses the core drivers of poor health outcomes: (1) medication adherence challenges, (2) social determinants of health, (3) polypharmacy, (4) team-based care with family support for deprescribing, and (5) psychosocial factors related to aging. METHODS: The SEA model was developed through a structured literature review focusing on medication safety, polypharmacy, behavioral health integration, home safety inspections and adherence. It draws on frameworks such as the Chronic Care Model, Interprofessional Collaborative Care for Older Adults, and Consolidated Framework for Implementation Research. This model fosters interdisciplinary collaboration by integrating pharmacists, primary care providers, mental health professionals, substance use treatment, and family suppowrt, and it is adaptable to diverse clinical settings. RESULTS: The SEA model assessed short- and long-term outcomes. Potential short-term effects included improved medication adherence, enhanced team coordination, and reduced occurrence of adverse drug events. Long-term goals and possible effects included better chronic disease management, fewer hospitalizations, and improved quality of life for older adults. The model's scalability allows for application across various healthcare settings, although further testing is required for validation. CONCLUSION: The SEA model provides a comprehensive framework for addressing the complex needs of older adults by focusing on medication SEA. Two vignettes, one clinical and one organizational, demonstrate the practical application of the model in patient care and implementation science. By improving interdisciplinary collaboration and addressing social and behavioral factors, in home safety for medications, this model aims to reduce polypharmacy and hospitalization. Based on existing evidence-based frameworks, this model would benefit from future studies to validate its effectiveness in diverse settings. AD - Integrated Health Psychology Training Program, The Wright Institute, Berkeley, CA, United States.; Doctor of Psychology Program, University of San Francisco, San Francisco, CA, United States.; John Muir Health, Family Medicine Residency Program, Walnut Creek, CA, United States.; Contra Costa Family Medicine Residency Program, Martinez, CA, United States.; LifeLong Medical Care, Oakland, CA, United States. AN - 40843417 BT - Front Public Health C5 - Healthcare Disparities; Education & Workforce DO - 10.3389/fpubh.2025.1453485 DP - NLM ET - 20250806 JF - Front Public Health LA - eng N2 - INTRODUCTION: Older adults face significant health risks owing to gaps in the management of polypharmacy and medication adherence, as well as the integration of physical and mental health needs. Current models do not fully address these challenges. This study introduced the Safety, Efficacy, and Adherence (SEA) model designed to enhance interdisciplinary collaboration, improve medication management, and integrate care for older adults. This model addresses the core drivers of poor health outcomes: (1) medication adherence challenges, (2) social determinants of health, (3) polypharmacy, (4) team-based care with family support for deprescribing, and (5) psychosocial factors related to aging. METHODS: The SEA model was developed through a structured literature review focusing on medication safety, polypharmacy, behavioral health integration, home safety inspections and adherence. It draws on frameworks such as the Chronic Care Model, Interprofessional Collaborative Care for Older Adults, and Consolidated Framework for Implementation Research. This model fosters interdisciplinary collaboration by integrating pharmacists, primary care providers, mental health professionals, substance use treatment, and family suppowrt, and it is adaptable to diverse clinical settings. RESULTS: The SEA model assessed short- and long-term outcomes. Potential short-term effects included improved medication adherence, enhanced team coordination, and reduced occurrence of adverse drug events. Long-term goals and possible effects included better chronic disease management, fewer hospitalizations, and improved quality of life for older adults. The model's scalability allows for application across various healthcare settings, although further testing is required for validation. CONCLUSION: The SEA model provides a comprehensive framework for addressing the complex needs of older adults by focusing on medication SEA. Two vignettes, one clinical and one organizational, demonstrate the practical application of the model in patient care and implementation science. By improving interdisciplinary collaboration and addressing social and behavioral factors, in home safety for medications, this model aims to reduce polypharmacy and hospitalization. Based on existing evidence-based frameworks, this model would benefit from future studies to validate its effectiveness in diverse settings. PY - 2025 SN - 2296-2565 SP - 1453485 ST - Enhancing primary care for older adults: the safety, efficacy, and adherence (SEA) team-based care model to reduce adverse medication outcomes T1 - Enhancing primary care for older adults: the safety, efficacy, and adherence (SEA) team-based care model to reduce adverse medication outcomes T2 - Front Public Health TI - Enhancing primary care for older adults: the safety, efficacy, and adherence (SEA) team-based care model to reduce adverse medication outcomes U1 - Healthcare Disparities; Education & Workforce U3 - 10.3389/fpubh.2025.1453485 VL - 13 VO - 2296-2565 Y1 - 2025 ER -