TY - JOUR AU - D. Palakshappa AU - K. N. Ray AU - K. Schweiberger AU - S. A. Berkowitz AU - J. Hanmer A1 - AB - Research suggests that household social risks are associated with worse mental health in adolescents, but prior studies have been limited. We evaluated the association between social risks and symptoms of depression and anxiety in adolescents 1 year later by conducting a retrospective cohort study at an integrated health system with 45 practices. Adolescents were screened for depression using the Patient Health Questionnaire-2 (PHQ-2) and anxiety using the Generalized Anxiety Disorder-2 (GAD-2). Of the 4748 adolescents, 1220 (25.7%) had at least 1 social risk, 226 (5.7%) reported symptoms of depression, and 410 (10.2%) reported symptoms of anxiety. Adolescents in households with at least 1 social risk were more likely to report symptoms of depression (β = 0.15, 95% confidence interval [CI] = 0.07-0.23) and anxiety (β = 0.21, 95% CI = 0.11-0.31) and had greater odds of a positive PHQ-2 (odds ratio [OR] = 1.50, 95% CI = 1.12-2.01) and positive GAD-2 (OR = 1.57; 95% CI = 1.32, 1.87). AD - Department of Pediatrics, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Department of Epidemiology and Prevention, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; University of Pittsburgh, Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.; Division of General Medicine and Clinical Epidemiology, Department of Medicine, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.; Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of General Internal Medicine, University of Pittsburgh, Pittsburgh, PA, USA. AN - 40914851 BT - Clin Pediatr (Phila) C5 - Healthcare Disparities DA - Sep 7 DO - 10.1177/00099228251372311 DP - NLM ET - 20250907 JF - Clin Pediatr (Phila) LA - eng N2 - Research suggests that household social risks are associated with worse mental health in adolescents, but prior studies have been limited. We evaluated the association between social risks and symptoms of depression and anxiety in adolescents 1 year later by conducting a retrospective cohort study at an integrated health system with 45 practices. Adolescents were screened for depression using the Patient Health Questionnaire-2 (PHQ-2) and anxiety using the Generalized Anxiety Disorder-2 (GAD-2). Of the 4748 adolescents, 1220 (25.7%) had at least 1 social risk, 226 (5.7%) reported symptoms of depression, and 410 (10.2%) reported symptoms of anxiety. Adolescents in households with at least 1 social risk were more likely to report symptoms of depression (β = 0.15, 95% confidence interval [CI] = 0.07-0.23) and anxiety (β = 0.21, 95% CI = 0.11-0.31) and had greater odds of a positive PHQ-2 (odds ratio [OR] = 1.50, 95% CI = 1.12-2.01) and positive GAD-2 (OR = 1.57; 95% CI = 1.32, 1.87). PY - 2025 SN - 0009-9228 SP - 99228251372311 ST - Relationship Between Household Social Risk and Symptoms of Depression and Anxiety in Adolescents: A Retrospective Cohort Study T1 - Relationship Between Household Social Risk and Symptoms of Depression and Anxiety in Adolescents: A Retrospective Cohort Study T2 - Clin Pediatr (Phila) TI - Relationship Between Household Social Risk and Symptoms of Depression and Anxiety in Adolescents: A Retrospective Cohort Study U1 - Healthcare Disparities U3 - 10.1177/00099228251372311 VO - 0009-9228 Y1 - 2025 ER -