TY - JOUR AU - A. M. Stroud AU - S. H. Curtis AU - I. B. Weir AU - J. J. Stout AU - B. A. Barry AU - W. V. Bobo AU - A. P. Athreya AU - R. R. Sharp A1 - AB - BACKGROUND: As artificial intelligence (AI) tools are integrated more widely in psychiatric medicine, it is important to consider the impact these tools will have on clinical practice. OBJECTIVE: This study aimed to characterize physician perspectives on the potential impact AI tools will have in psychiatric medicine. METHODS: We interviewed 42 physicians (21 psychiatrists and 21 family medicine practitioners). These interviews used detailed clinical case scenarios involving the use of AI technologies in the evaluation, diagnosis, and treatment of psychiatric conditions. Interviews were transcribed and subsequently analyzed using qualitative analysis methods. RESULTS: Physicians highlighted multiple potential benefits of AI tools, including potential support for optimizing pharmaceutical efficacy, reducing administrative burden, aiding shared decision-making, and increasing access to health services, and were optimistic about the long-term impact of these technologies. This optimism was tempered by concerns about potential near-term risks to both patients and themselves including misguiding clinical judgment, increasing clinical burden, introducing patient harms, and creating legal liability. CONCLUSIONS: Our results highlight the importance of considering specialist perspectives when deploying AI tools in psychiatric medicine. AD - Biomedical Ethics Program, Mayo Clinic, Rochester, MN, United States.; Alix School of Medicine, Mayo Clinic, Rochester, MN, United States.; Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, United States.; Department of Behavioral Sciences & Social Medicine, College of Medicine, Florida State University, Tallahassee, FL, United States.; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, United States. AN - 39928397 BT - JMIR Ment Health C5 - Education & Workforce; HIT & Telehealth DA - Feb 10 DO - 10.2196/64414 DP - NLM ET - 20250210 JF - JMIR Ment Health LA - eng N2 - BACKGROUND: As artificial intelligence (AI) tools are integrated more widely in psychiatric medicine, it is important to consider the impact these tools will have on clinical practice. OBJECTIVE: This study aimed to characterize physician perspectives on the potential impact AI tools will have in psychiatric medicine. METHODS: We interviewed 42 physicians (21 psychiatrists and 21 family medicine practitioners). These interviews used detailed clinical case scenarios involving the use of AI technologies in the evaluation, diagnosis, and treatment of psychiatric conditions. Interviews were transcribed and subsequently analyzed using qualitative analysis methods. RESULTS: Physicians highlighted multiple potential benefits of AI tools, including potential support for optimizing pharmaceutical efficacy, reducing administrative burden, aiding shared decision-making, and increasing access to health services, and were optimistic about the long-term impact of these technologies. This optimism was tempered by concerns about potential near-term risks to both patients and themselves including misguiding clinical judgment, increasing clinical burden, introducing patient harms, and creating legal liability. CONCLUSIONS: Our results highlight the importance of considering specialist perspectives when deploying AI tools in psychiatric medicine. PY - 2025 SN - 2368-7959 SP - e64414 ST - Physician Perspectives on the Potential Benefits and Risks of Applying Artificial Intelligence in Psychiatric Medicine: Qualitative Study T1 - Physician Perspectives on the Potential Benefits and Risks of Applying Artificial Intelligence in Psychiatric Medicine: Qualitative Study T2 - JMIR Ment Health TI - Physician Perspectives on the Potential Benefits and Risks of Applying Artificial Intelligence in Psychiatric Medicine: Qualitative Study U1 - Education & Workforce; HIT & Telehealth U3 - 10.2196/64414 VL - 12 VO - 2368-7959 Y1 - 2025 ER -