TY - JOUR AU - M. Petrides AU - A. Peletidi AU - E. Nena AU - T. Constantinidis AU - C. Kontogiorgis A1 - AB - BACKGROUND: Approximately 50 million individuals across the globe are impacted by epilepsy, leading to fear, discrimination, psychiatric issues, high costs, and social stigma. Proper diagnosis and treatment could allow up to 70% of those affected to live seizure-free. Community pharmacists have significant potential to actively participate in epilepsy patient care, beyond merely dispensing medications. The objective of this study was to systematically review and assess the roles of pharmacists in epilepsy care, focusing on pharmacist-led interventions and services for patients with epilepsy. METHODS: Following PRISMA 2020 guidelines, the review included cross-sectional, retrospective cohort, and qualitative/quantitative studies on pharmacist-led epilepsy interventions in community and outpatient settings. Searches were conducted in Scopus, PubMed Central, and Science Direct for studies published through the end of 2023. Two evaluators independently reviewed and chose studies, and the data was analysed using Microsoft Excel®. Quality assessment was performed using the MMAT tool. RESULTS: Five eligible studies were included, covering 457 participants. Studies originated from the USA (n = 3), Netherlands (n = 1), and Palestine (n = 1). They evaluated pharmacist-led interventions in epilepsy, including medication adherence, quality of life, and pharmacist's integration in epilepsy care. CONCLUSION: This review underscores the possible contributions of pharmacists in epilepsy care, stressing the importance of pharmacist-led interventions to enhance medication adherence and the quality of life for individuals with epilepsy. Future research should evaluate the effectiveness and cost-effectiveness of these services, including disease management and patient education. Increasing awareness among pharmacists and patients about pharmacists' contributions is crucial for improving epilepsy care. AD - Pharmacy Programme, Department of Health Sciences, School of Life and Health Sciences, University of Nicosia, Nicosia, Cyprus.; Laboratory of Hygiene and Environmental Protection, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.; Bioactive Molecules Research Center, School of Life and Health Sciences, University of Nicosia, Nicosia, Cyprus. AN - 40224172 BT - J Pharm Policy Pract C5 - Education & Workforce CP - 1 DO - 10.1080/20523211.2025.2487046 DP - NLM ET - 20250410 IS - 1 JF - J Pharm Policy Pract LA - eng N2 - BACKGROUND: Approximately 50 million individuals across the globe are impacted by epilepsy, leading to fear, discrimination, psychiatric issues, high costs, and social stigma. Proper diagnosis and treatment could allow up to 70% of those affected to live seizure-free. Community pharmacists have significant potential to actively participate in epilepsy patient care, beyond merely dispensing medications. The objective of this study was to systematically review and assess the roles of pharmacists in epilepsy care, focusing on pharmacist-led interventions and services for patients with epilepsy. METHODS: Following PRISMA 2020 guidelines, the review included cross-sectional, retrospective cohort, and qualitative/quantitative studies on pharmacist-led epilepsy interventions in community and outpatient settings. Searches were conducted in Scopus, PubMed Central, and Science Direct for studies published through the end of 2023. Two evaluators independently reviewed and chose studies, and the data was analysed using Microsoft Excel®. Quality assessment was performed using the MMAT tool. RESULTS: Five eligible studies were included, covering 457 participants. Studies originated from the USA (n = 3), Netherlands (n = 1), and Palestine (n = 1). They evaluated pharmacist-led interventions in epilepsy, including medication adherence, quality of life, and pharmacist's integration in epilepsy care. CONCLUSION: This review underscores the possible contributions of pharmacists in epilepsy care, stressing the importance of pharmacist-led interventions to enhance medication adherence and the quality of life for individuals with epilepsy. Future research should evaluate the effectiveness and cost-effectiveness of these services, including disease management and patient education. Increasing awareness among pharmacists and patients about pharmacists' contributions is crucial for improving epilepsy care. PY - 2025 SN - 2052-3211 (Print); 2052-3211 SP - 2487046 ST - The role of pharmacists in enhancing epilepsy care: a systematic review of community and outpatient interventions T1 - The role of pharmacists in enhancing epilepsy care: a systematic review of community and outpatient interventions T2 - J Pharm Policy Pract TI - The role of pharmacists in enhancing epilepsy care: a systematic review of community and outpatient interventions U1 - Education & Workforce U3 - 10.1080/20523211.2025.2487046 VL - 18 VO - 2052-3211 (Print); 2052-3211 Y1 - 2025 ER -