TY - JOUR
AU - V. Mugada
AU - S. S. S. Allada
AU - Rvs Koppala
AU - S. R. Yarguntla
A1 - 
AB - OBJECTIVES: The multidisciplinary team approach improves adverse drug reaction (ADR) reporting and management. Our study aims to integrate a pharmacovigilance (PV) and Response Team within the general medicine department to improve ADR reporting and management. MATERIALS AND METHODS: We conducted a prospective cross-sectional study for seven months in four general medicine wards. We proposed a PV and response unit team (PRUT), comprising a nursing student, and a Doctor of Pharmacy (intern). After the team received interventional educational training, we integrated them with the physician and head nurse of each general medicine inpatient ward. We then evaluated the effectiveness of the team in ADR reporting and management using a feedback survey. RESULTS: In this study, comorbidities (30.69%) and polypharmacy (≥5 drugs) (26.25%) were major predisposing factors. Among drug-related problems in 125 patients, inappropriate drug use (28.80%) and unclear dose timing (21.60%) were predominant. Gastrointestinal disorders were common (44.73%), with dose adjustment being the top management strategy (36.84%). Over 71% supported the PRUT for improving patient safety and reducing medication errors, noting high effectiveness in consultation (85.92%) and in reducing the ADR reporting burden (87.32%). There is a statistically significant association between the level of agreement on the effectiveness of PRUT among healthcare professionals (p<0.01). Most healthcare professionals agreed on PRUT's effectiveness without any reports of low agreement levels. CONCLUSION: The PRUT effectively reported and managed ADRs. A multidisciplinary approach improves ADR reporting and management.
AD - Vignan Institute of Pharmaceutical Technology, Department of Pharmacy Practice, Duvvada, India.; Vignan Institute of Pharmaceutical Technology, Department of Pharmacology, Duvvada, India.; Vignan Institute of Pharmaceutical Technology, Department of Pharmaceutics, Duvvada, India.
AN - 40366197
BT - Turk J Pharm Sci
C5 - Opioids & Substance Use; Education & Workforce
CP - 2
DA - May 14
DO - 10.4274/tjps.galenos.2025.44902
DP - NLM
IS - 2
JF - Turk J Pharm Sci
LA - eng
N2 - OBJECTIVES: The multidisciplinary team approach improves adverse drug reaction (ADR) reporting and management. Our study aims to integrate a pharmacovigilance (PV) and Response Team within the general medicine department to improve ADR reporting and management. MATERIALS AND METHODS: We conducted a prospective cross-sectional study for seven months in four general medicine wards. We proposed a PV and response unit team (PRUT), comprising a nursing student, and a Doctor of Pharmacy (intern). After the team received interventional educational training, we integrated them with the physician and head nurse of each general medicine inpatient ward. We then evaluated the effectiveness of the team in ADR reporting and management using a feedback survey. RESULTS: In this study, comorbidities (30.69%) and polypharmacy (≥5 drugs) (26.25%) were major predisposing factors. Among drug-related problems in 125 patients, inappropriate drug use (28.80%) and unclear dose timing (21.60%) were predominant. Gastrointestinal disorders were common (44.73%), with dose adjustment being the top management strategy (36.84%). Over 71% supported the PRUT for improving patient safety and reducing medication errors, noting high effectiveness in consultation (85.92%) and in reducing the ADR reporting burden (87.32%). There is a statistically significant association between the level of agreement on the effectiveness of PRUT among healthcare professionals (p<0.01). Most healthcare professionals agreed on PRUT's effectiveness without any reports of low agreement levels. CONCLUSION: The PRUT effectively reported and managed ADRs. A multidisciplinary approach improves ADR reporting and management.
PY - 2025
SN - 1304-530X (Print); 1304-530x
SP - 83
EP - 90+
ST - Integrating a Pharmacovigilance and Response Unit Team for a Better Adverse Drug Reaction Reporting and Management: Insights from a Prospective Cross-Sectional Study
T1 - Integrating a Pharmacovigilance and Response Unit Team for a Better Adverse Drug Reaction Reporting and Management: Insights from a Prospective Cross-Sectional Study
T2 - Turk J Pharm Sci
TI - Integrating a Pharmacovigilance and Response Unit Team for a Better Adverse Drug Reaction Reporting and Management: Insights from a Prospective Cross-Sectional Study
U1 - Opioids & Substance Use; Education & Workforce
U3 - 10.4274/tjps.galenos.2025.44902
VL - 22
VO - 1304-530X (Print); 1304-530x
Y1 - 2025
ER -