TY - JOUR
AU - C. Parker
AU - E. Whalen
AU - M. A. Smith
AU - J. Becerra
AU - L. Stevens
AU - C. M. Avitabile
AU - A. Brown
AU - M. Cash
AU - E. O. Jackson
AU - J. McSweeney
AU - K. Miller-Reed
AU - J. T. Reyes
AU - C. Sheppard
AU - M. P. Mullen
A1 - 
AB - Children with chronic diseases, including pulmonary hypertension (PH), have an increased risk of anxiety and depression (AD), impacting mental health (MH), and quality of life (QoL). We sought to characterize the prevalence of AD in pediatric PH and identify associated factors. We developed a prospective cross-sectional study with 10 Pediatric Pulmonary Hypertension Network (PPHNet) centers. Eligible subjects aged 12-21, diagnosed with PH, and English or Spanish speaking, completed validated AD screening questionnaires during routine outpatient clinic visits. Caregivers provided socioeconomic status (SES) data and MH history via survey. Patient demographics and clinical characteristics were analyzed using standard descriptive statistics. Eighty-eight patients were enrolled (female = 54, 61%). Forty-six (51.7%) identified at least mild symptoms of AD. Females were more likely to report AD than males (OR 2.67, 95% CI 1.11-6.61, p = 0.030). There were no significant associations between AD and PH severity, MH history, family dynamics, SES status, race, or ethnicity. Twenty-seven of those patients (58.7%) received MH education/counseling by MH professionals; ten (21.7%) were referred to MH providers, and nine patients (19.6%) were assessed for suicide safety. Adolescents with PH have a high prevalence of AD. Female patients had increased AD compared to male patients; no other predictors were linked to the prevalence of AD. Routine AD screening should be integrated into outpatient PH clinic visits with a focus on psychosocial support for young females diagnosed with PH.
AD - Department of Nursing University of California, San Francisco San Francisco California USA.; Department of Pulmonary Medicine Texas Children's Hospital Houston Texas USA.; Department of Pediatrics University of California San Francisco Benioff Children's Hospital San Francisco California USA.; Department of Pediatrics University of Pennsylvania Perelman School of Medicine, Division of Cardiology, The Children's Hospital of Philadelphia Philadelphia Pennsylvania USA.; Division of Pulmonary Medicine, Department of Pediatrics Vanderbilt Children's Hospital Nashville Tennessee USA.; Department of Cardiology Cincinnati Children's Hospital Cincinnati Ohio USA.; Department of Cardiology Seattle Children's Hospital Seattle Washington USA.; Patient Care Operations and Department of Cardiology Boston Children's Hospital Boston Massachusetts USA.; Department of Cardiology Children's Hospital of Colorado Aurora Colorado USA.; Division of Cardiology, The Hospital for Sick Children University of Toronto Toronto Ontario Canada.; Department of Pediatric Cardiac Intensive Care Stollery Children's Hospital Edmonton Alberta Canada.; Department of Pediatrics Harvard Medical School Boston Massachusetts USA.
AN - 40567293
BT - Pulm Circ
C5 - Healthcare Disparities; Medically Unexplained Symptoms
CP - 2
DA - Apr
DO - 10.1002/pul2.70117
DP - NLM
ET - 20250624
IS - 2
JF - Pulm Circ
LA - eng
N2 - Children with chronic diseases, including pulmonary hypertension (PH), have an increased risk of anxiety and depression (AD), impacting mental health (MH), and quality of life (QoL). We sought to characterize the prevalence of AD in pediatric PH and identify associated factors. We developed a prospective cross-sectional study with 10 Pediatric Pulmonary Hypertension Network (PPHNet) centers. Eligible subjects aged 12-21, diagnosed with PH, and English or Spanish speaking, completed validated AD screening questionnaires during routine outpatient clinic visits. Caregivers provided socioeconomic status (SES) data and MH history via survey. Patient demographics and clinical characteristics were analyzed using standard descriptive statistics. Eighty-eight patients were enrolled (female = 54, 61%). Forty-six (51.7%) identified at least mild symptoms of AD. Females were more likely to report AD than males (OR 2.67, 95% CI 1.11-6.61, p = 0.030). There were no significant associations between AD and PH severity, MH history, family dynamics, SES status, race, or ethnicity. Twenty-seven of those patients (58.7%) received MH education/counseling by MH professionals; ten (21.7%) were referred to MH providers, and nine patients (19.6%) were assessed for suicide safety. Adolescents with PH have a high prevalence of AD. Female patients had increased AD compared to male patients; no other predictors were linked to the prevalence of AD. Routine AD screening should be integrated into outpatient PH clinic visits with a focus on psychosocial support for young females diagnosed with PH.
PY - 2025
SN - 2045-8932 (Print); 2045-8932
SP - e70117
ST - Anxiety and Depression Screening of Youth in Pediatric Pulmonary Hypertension Clinic: A Multi-Center, Cross-Sectional Study
T1 - Anxiety and Depression Screening of Youth in Pediatric Pulmonary Hypertension Clinic: A Multi-Center, Cross-Sectional Study
T2 - Pulm Circ
TI - Anxiety and Depression Screening of Youth in Pediatric Pulmonary Hypertension Clinic: A Multi-Center, Cross-Sectional Study
U1 - Healthcare Disparities; Medically Unexplained Symptoms
U3 - 10.1002/pul2.70117
VL - 15
VO - 2045-8932 (Print); 2045-8932
Y1 - 2025
ER -