TY - JOUR AU - M. F. Brunette AU - J. G. Bourassa AU - J. C. Ferron AU - K. A. Aschbrenner AU - M. M. Santos AU - M. A. Gowarty AU - S. I. Pratt A1 - AB - People with serious mental illness (SMI) are more likely to smoke and less likely to quit than the general population. More effective and accessible cessation treatments are needed to promote health and prevent disease in this disparity population. To this end, we optimized a multicomponent health promotion intervention tailored for people with SMI, Breathe Well, Live Well, and conducted a quasi-experimental program evaluation to assess program feasibility and effectiveness compared with a usual care comparison condition consisting of "The 3 As." Community mental health center staff trained as health coaches delivered eight telehealth Breathe Well, Live Well sessions over 4 months to individuals. Breathe Well, Live Well content included cognitive behavioral therapy (CBT)-based counseling, pharmacotherapy support, incentivized app use (National Cancer Institute's quitSTART), and social support person coaching. Participants were 170 integrated mental health and primary care service recipients with SMI who smoked daily; 53 Breathe Well, Live Well and 117 comparison participants were enrolled during February 2020 through July 2022. Effectiveness was measured via biologically verified abstinence; feasibility was measured via Breathe Well, Live Well intervention engagement. Participants of Breathe Well, Live Well were about three times more likely to be abstinent at follow-up compared with comparison participants. Among those still smoking, Breathe Well, Live Well participants were about five times more likely to have decreased their daily cigarette consumption by at least half. Intervention engagement was strong for pharmacotherapy, counseling, and incentivized quitSTART app use, indicating that these components were feasible to deliver by community mental health center staff. AD - Dartmouth Health, Lebanon, NH, USA.; Geisel School of Medicine at Dartmouth, Hanover, NH, USA.; New Hampshire Department of Health and Human Services, Concord, NH, USA. AN - 40575927 BT - Health Promot Pract C5 - Opioids & Substance Use; Healthcare Disparities DA - Jun 27 DO - 10.1177/15248399251348169 DP - NLM ET - 20250627 JF - Health Promot Pract LA - eng N2 - People with serious mental illness (SMI) are more likely to smoke and less likely to quit than the general population. More effective and accessible cessation treatments are needed to promote health and prevent disease in this disparity population. To this end, we optimized a multicomponent health promotion intervention tailored for people with SMI, Breathe Well, Live Well, and conducted a quasi-experimental program evaluation to assess program feasibility and effectiveness compared with a usual care comparison condition consisting of "The 3 As." Community mental health center staff trained as health coaches delivered eight telehealth Breathe Well, Live Well sessions over 4 months to individuals. Breathe Well, Live Well content included cognitive behavioral therapy (CBT)-based counseling, pharmacotherapy support, incentivized app use (National Cancer Institute's quitSTART), and social support person coaching. Participants were 170 integrated mental health and primary care service recipients with SMI who smoked daily; 53 Breathe Well, Live Well and 117 comparison participants were enrolled during February 2020 through July 2022. Effectiveness was measured via biologically verified abstinence; feasibility was measured via Breathe Well, Live Well intervention engagement. Participants of Breathe Well, Live Well were about three times more likely to be abstinent at follow-up compared with comparison participants. Among those still smoking, Breathe Well, Live Well participants were about five times more likely to have decreased their daily cigarette consumption by at least half. Intervention engagement was strong for pharmacotherapy, counseling, and incentivized quitSTART app use, indicating that these components were feasible to deliver by community mental health center staff. PY - 2025 SN - 1524-8399 (Print); 1524-8399 SP - 15248399251348169 ST - Program Evaluation for a Novel Multicomponent Smoking Cessation Intervention for Smokers With Serious Mental Illness T1 - Program Evaluation for a Novel Multicomponent Smoking Cessation Intervention for Smokers With Serious Mental Illness T2 - Health Promot Pract TI - Program Evaluation for a Novel Multicomponent Smoking Cessation Intervention for Smokers With Serious Mental Illness U1 - Opioids & Substance Use; Healthcare Disparities U3 - 10.1177/15248399251348169 VO - 1524-8399 (Print); 1524-8399 Y1 - 2025 ER -