TY - JOUR AU - M. R. Vilensky AU - N. A. Arrato AU - K. M. Carpenter A1 - AB - Pregnant women with opioid use disorder show elevated rates of comorbid mental health problems, both of which are associated with negative health outcomes for mothers and children. There is substantial evidence supporting the benefits of treatment of perinatal opioid use disorder, as well as perinatal depression and anxiety, but there are gaps in knowledge about the effectiveness of perinatal behavioral health interventions in the context of co-occurring substance use disorder. The current study seeks to address this gap by examining outcomes of a behavioral activation treatment in a group of peripartum women with opioid use disorder (N = 68). Behavioral activation has shown promise in treating co-occurring depression and substance use problems. The intervention was delivered as part of an integrated care treatment model, in which patients received co-located obstetric, substance use, and mental health care in a hospital-based clinic. Hierarchical linear modeling was used to assess change in symptoms over time. Results suggest that the group behavioral activation intervention was associated with reduced depression and anxiety symptoms, demonstrated by significant reductions in PHQ-9 and GAD-7 scores over the course of treatment. Moreover, there were indications that increased attendance was associated with further reductions in depressive symptoms. Results contribute to understanding the effectiveness of behavioral activation in the context of peripartum opioid use disorder. Findings also add to the evidence supporting integrated care models and offer a potential blueprint for improving outcomes and reducing barriers to care in this population. AD - Department of Psychiatry and Behavioral Health, The Ohio State University, Columbus, OH, USA. Michael.Vilensky@osumc.edu.; Department of Psychology, The Ohio State University, Columbus, OH, USA.; Department of Psychiatry and Behavioral Health, The Ohio State University, Columbus, OH, USA. AN - 38753283 BT - J Clin Psychol Med Settings C5 - Healthcare Disparities; Opioids & Substance Use CP - 1 DA - Mar DO - 10.1007/s10880-023-09984-y DP - NLM ET - 20240516 IS - 1 JF - J Clin Psychol Med Settings LA - eng N2 - Pregnant women with opioid use disorder show elevated rates of comorbid mental health problems, both of which are associated with negative health outcomes for mothers and children. There is substantial evidence supporting the benefits of treatment of perinatal opioid use disorder, as well as perinatal depression and anxiety, but there are gaps in knowledge about the effectiveness of perinatal behavioral health interventions in the context of co-occurring substance use disorder. The current study seeks to address this gap by examining outcomes of a behavioral activation treatment in a group of peripartum women with opioid use disorder (N = 68). Behavioral activation has shown promise in treating co-occurring depression and substance use problems. The intervention was delivered as part of an integrated care treatment model, in which patients received co-located obstetric, substance use, and mental health care in a hospital-based clinic. Hierarchical linear modeling was used to assess change in symptoms over time. Results suggest that the group behavioral activation intervention was associated with reduced depression and anxiety symptoms, demonstrated by significant reductions in PHQ-9 and GAD-7 scores over the course of treatment. Moreover, there were indications that increased attendance was associated with further reductions in depressive symptoms. Results contribute to understanding the effectiveness of behavioral activation in the context of peripartum opioid use disorder. Findings also add to the evidence supporting integrated care models and offer a potential blueprint for improving outcomes and reducing barriers to care in this population. PY - 2025 SN - 1068-9583 (Print); 1068-9583 SP - 19 EP - 26+ ST - Effectiveness of a Behavioral Activation Intervention for Peripartum Women with Opioid Use Disorder T1 - Effectiveness of a Behavioral Activation Intervention for Peripartum Women with Opioid Use Disorder T2 - J Clin Psychol Med Settings TI - Effectiveness of a Behavioral Activation Intervention for Peripartum Women with Opioid Use Disorder U1 - Healthcare Disparities; Opioids & Substance Use U3 - 10.1007/s10880-023-09984-y VL - 32 VO - 1068-9583 (Print); 1068-9583 Y1 - 2025 ER -