TY - JOUR AU - R. Sippy AU - L. Efstathopoulou AU - E. Simes AU - M. Davis AU - S. Howell AU - B. Morris AU - O. Owrid AU - N. Stoll AU - P. Fonagy AU - A. Moore A1 - AB - AIMS: Developing integrated mental health services focused on the needs of children and young people is a key policy goal in England. The THRIVE Framework and its implementation programme, i-THRIVE, are widely used in England. This study examines experiences of staff using i-THRIVE, estimates its effectiveness, and assesses how local system working relationships influence programme success. METHODS: This evaluation uses a quasi-experimental design (10 implementation and 10 comparison sites.) Measurements included staff surveys and assessment of 'THRIVE-like' features of each site. Additional site-level characteristics were collected from health system reports. The effect of i-THRIVE was evaluated using a four-group propensity-score-weighted difference-in-differences model; the moderating effect of system working relationships was evaluated with a difference-in-difference-in-differences model. RESULTS: Implementation site staff were more likely to report using THRIVE and more knowledgeable of THRIVE principles than comparison site staff. The mean improvement of fidelity scores among i-THRIVE sites was 16.7, and 8.8 among comparison sites; the weighted model did not find a statistically significant difference. However, results show that strong working relationships in the local system significantly enhance the effectiveness of i-THRIVE. Sites with highly effective working relationships showed a notable improvement in 'THRIVE-like' features, with an average increase of 16.41 points (95% confidence interval: 1.69-31.13, P-value: 0.031) over comparison sites. Sites with ineffective working relationships did not benefit from i-THRIVE (-2.76, 95% confidence interval: - 18.25-12.73, P-value: 0.708). CONCLUSIONS: The findings underscore the importance of working relationship effectiveness in the successful adoption and implementation of multi-agency health policies like i-THRIVE. AD - Department of Psychiatry, University of Cambridge, Cambridge, UK.; Anna Freud, London, UK.; Department of Department of Clinical, Educational and Health Psychology, University College London, London, UK. AN - 40135635 BT - Epidemiol Psychiatr Sci C5 - Education & Workforce DA - Mar 26 DO - 10.1017/s2045796025000101 DP - NLM ET - 20250326 JF - Epidemiol Psychiatr Sci LA - eng N2 - AIMS: Developing integrated mental health services focused on the needs of children and young people is a key policy goal in England. The THRIVE Framework and its implementation programme, i-THRIVE, are widely used in England. This study examines experiences of staff using i-THRIVE, estimates its effectiveness, and assesses how local system working relationships influence programme success. METHODS: This evaluation uses a quasi-experimental design (10 implementation and 10 comparison sites.) Measurements included staff surveys and assessment of 'THRIVE-like' features of each site. Additional site-level characteristics were collected from health system reports. The effect of i-THRIVE was evaluated using a four-group propensity-score-weighted difference-in-differences model; the moderating effect of system working relationships was evaluated with a difference-in-difference-in-differences model. RESULTS: Implementation site staff were more likely to report using THRIVE and more knowledgeable of THRIVE principles than comparison site staff. The mean improvement of fidelity scores among i-THRIVE sites was 16.7, and 8.8 among comparison sites; the weighted model did not find a statistically significant difference. However, results show that strong working relationships in the local system significantly enhance the effectiveness of i-THRIVE. Sites with highly effective working relationships showed a notable improvement in 'THRIVE-like' features, with an average increase of 16.41 points (95% confidence interval: 1.69-31.13, P-value: 0.031) over comparison sites. Sites with ineffective working relationships did not benefit from i-THRIVE (-2.76, 95% confidence interval: - 18.25-12.73, P-value: 0.708). CONCLUSIONS: The findings underscore the importance of working relationship effectiveness in the successful adoption and implementation of multi-agency health policies like i-THRIVE. PY - 2025 SN - 2045-7960 (Print); 2045-7960 SP - e21 ST - Effect of a needs-based model of care on the characteristics of healthcare services in England: the i-THRIVE National Implementation Programme T1 - Effect of a needs-based model of care on the characteristics of healthcare services in England: the i-THRIVE National Implementation Programme T2 - Epidemiol Psychiatr Sci TI - Effect of a needs-based model of care on the characteristics of healthcare services in England: the i-THRIVE National Implementation Programme U1 - Education & Workforce U3 - 10.1017/s2045796025000101 VL - 34 VO - 2045-7960 (Print); 2045-7960 Y1 - 2025 ER -