TY - JOUR
AU - P. Liu
AU - P. T. Korthuis
AU - B. M. Buchheit
A1 - 
AB - Opioid use disorder continues to drive overdose deaths in many countries, including the United States. Illicit fentanyl and its analogues have emerged as key contributors to the complications and mortality associated with opioid use disorder. Medications for opioid use disorder treatment, such as methadone and buprenorphine, are safe and substantially reduce opioid use, infectious complications, and mortality risk, but remain underutilized. Polysubstance use and emerging substances such as xylazine and designer benzodiazepines create additional treatment challenges. Recent clinical and policy innovations in treatment delivery, including telemedicine, bridge clinics, and expanded models for accessing methadone have the potential to increase access to life-saving care for people living with opioid use disorder.
AD - Section of Addiction, Division of General Internal Medicine & Geriatrics, Department of Medicine, Oregon Health & Science University, Portland, Oregon, USA; email: buchheit@ohsu.edu.; Oregon Health & Science University-Portland State University School of Public Health, Portland, Oregon, USA.; Department of Family Medicine, Oregon Health & Science University, Portland, Oregon, USA.
AN - 37827194
BT - Annu Rev Med
C5 - Opioids & Substance Use
DA - Jan 29
DO - 10.1146/annurev-med-050522-033924
DP - NLM
ET - 20231012
JF - Annu Rev Med
LA - eng
N2 - Opioid use disorder continues to drive overdose deaths in many countries, including the United States. Illicit fentanyl and its analogues have emerged as key contributors to the complications and mortality associated with opioid use disorder. Medications for opioid use disorder treatment, such as methadone and buprenorphine, are safe and substantially reduce opioid use, infectious complications, and mortality risk, but remain underutilized. Polysubstance use and emerging substances such as xylazine and designer benzodiazepines create additional treatment challenges. Recent clinical and policy innovations in treatment delivery, including telemedicine, bridge clinics, and expanded models for accessing methadone have the potential to increase access to life-saving care for people living with opioid use disorder.
PY - 2024
SN - 0066-4219
SP - 83
EP - 97+
ST - Novel Therapeutic and Program-Based Approaches to Opioid Use Disorders
T1 - Novel Therapeutic and Program-Based Approaches to Opioid Use Disorders
T2 - Annu Rev Med
TI - Novel Therapeutic and Program-Based Approaches to Opioid Use Disorders
U1 - Opioids & Substance Use
U3 - 10.1146/annurev-med-050522-033924
VL - 75
VO - 0066-4219
Y1 - 2024
ER -