TY - JOUR
AU - R. Byng
AU - S. Creanor
AU - B. Jones
AU - J. Hosking
AU - H. Plappert
AU - S. Bevan
AU - N. Britten
AU - M. Clark
AU - L. Davies
AU - J. Frost
AU - L. Gask
AU - B. Gibbons
AU - J. Gibson
AU - P. Hardy
AU - C. Hobson-Merrett
AU - P. Huxley
AU - A. Jeffery
AU - S. Marwaha
AU - T. Rawcliffe
AU - S. Reilly
AU - D. Richards
AU - R. Sayers
AU - L. Williams
AU - V. Pinfold
AU - M. Birchwood
A1 - 
AB - BACKGROUND: Individuals living with severe mental illness can have significant emotional, physical and social challenges. Collaborative care combines clinical and organisational components. AIMS: We tested whether a primary care-based collaborative care model (PARTNERS) would improve quality of life for people with diagnoses of schizophrenia, bipolar disorder or other psychoses, compared with usual care. METHOD: We conducted a general practice-based, cluster randomised controlled superiority trial. Practices were recruited from four English regions and allocated (1:1) to intervention or control. Individuals receiving limited input in secondary care or who were under primary care only were eligible. The 12-month PARTNERS intervention incorporated person-centred coaching support and liaison work. The primary outcome was quality of life as measured by the Manchester Short Assessment of Quality of Life (MANSA). RESULTS: We allocated 39 general practices, with 198 participants, to the PARTNERS intervention (20 practices, 116 participants) or control (19 practices, 82 participants). Primary outcome data were available for 99 (85.3%) intervention and 71 (86.6%) control participants. Mean change in overall MANSA score did not differ between the groups (intervention: 0.25, s.d. 0.73; control: 0.21, s.d. 0.86; estimated fully adjusted between-group difference 0.03, 95% CI -0.25 to 0.31; P = 0.819). Acute mental health episodes (safety outcome) included three crises in the intervention group and four in the control group. CONCLUSIONS: There was no evidence of a difference in quality of life, as measured with the MANSA, between those receiving the PARTNERS intervention and usual care. Shifting care to primary care was not associated with increased adverse outcomes.
AD - Community and Primary Care Research Group, University of Plymouth, UK.;Department of Health and Community Sciences, University of Exeter, UK.;Institute for Mental Health, University of Birmingham, UK.;Birmingham Clinical Trials Unit, University of Birmingham, UK.;Care Policy and Evaluation Centre, London School of Economics and Political Science, UK.;Division of Population Health, University of Manchester, UK.;Institute for Mental Health, Coventry and Warwickshire Partnership NHS Trust, UK.;The McPin Foundation, UK.;National Perinatal Epidemiology Unit, Oxford Population Health, Nuffield Department of Population Health, University of Oxford, UK.;School of Medical and Health Sciences, University of Bangor, UK.;Institute for Mental Health, University of Birmingham, UK; and Institute for Mental Health, Birmingham and Solihull Mental Health NHS Foundation Trust, UK.;Lancashire Care NHS Trust, UK.;Centre for Applied Dementia Studies, Faculty of Health Studies, University of Bradford, UK.;Health Sciences, University of Warwick, UK.
AN - 37078520
BT - Br J Psychiatry
C5 - Healthcare Disparities; Measures
CP - 6
DA - Jun
DO - 10.1192/bjp.2023.28
DP - NLM
IS - 6
JF - Br J Psychiatry
LA - eng
N2 - BACKGROUND: Individuals living with severe mental illness can have significant emotional, physical and social challenges. Collaborative care combines clinical and organisational components. AIMS: We tested whether a primary care-based collaborative care model (PARTNERS) would improve quality of life for people with diagnoses of schizophrenia, bipolar disorder or other psychoses, compared with usual care. METHOD: We conducted a general practice-based, cluster randomised controlled superiority trial. Practices were recruited from four English regions and allocated (1:1) to intervention or control. Individuals receiving limited input in secondary care or who were under primary care only were eligible. The 12-month PARTNERS intervention incorporated person-centred coaching support and liaison work. The primary outcome was quality of life as measured by the Manchester Short Assessment of Quality of Life (MANSA). RESULTS: We allocated 39 general practices, with 198 participants, to the PARTNERS intervention (20 practices, 116 participants) or control (19 practices, 82 participants). Primary outcome data were available for 99 (85.3%) intervention and 71 (86.6%) control participants. Mean change in overall MANSA score did not differ between the groups (intervention: 0.25, s.d. 0.73; control: 0.21, s.d. 0.86; estimated fully adjusted between-group difference 0.03, 95% CI -0.25 to 0.31; P = 0.819). Acute mental health episodes (safety outcome) included three crises in the intervention group and four in the control group. CONCLUSIONS: There was no evidence of a difference in quality of life, as measured with the MANSA, between those receiving the PARTNERS intervention and usual care. Shifting care to primary care was not associated with increased adverse outcomes.
PY - 2023
SN - 0007-1250 (Print);0007-1250
SP - 246
EP - 256+
ST - The effectiveness of a primary care-based collaborative care model to improve quality of life in people with severe mental illness: PARTNERS2 cluster randomised controlled trial
T1 - The effectiveness of a primary care-based collaborative care model to improve quality of life in people with severe mental illness: PARTNERS2 cluster randomised controlled trial
T2 - Br J Psychiatry
TI - The effectiveness of a primary care-based collaborative care model to improve quality of life in people with severe mental illness: PARTNERS2 cluster randomised controlled trial
U1 - Healthcare Disparities; Measures
U3 - 10.1192/bjp.2023.28
VL - 222
VO - 0007-1250 (Print);0007-1250
Y1 - 2023
ER -