TY - JOUR KW - Buprenorphine, Naloxone Drug Combination KW - Drug Combinations KW - Humans KW - Narcotic Antagonists KW - Opioid-Related Disorders/drug therapy KW - Substance Withdrawal Syndrome/etiology AU - Eric Urnoski A1 - AB - Combination buprenorphine-naloxone is a cornerstone of outpatient treatment for substance use disorder, and is more widely accessible in primary care. Because oral buprenorphine has been diverted and abused for its euphoric properties, a combination formulation was developed and will trigger withdrawal symptoms if injected IV. AD - Eric Urnoski is a clinical pharmacist in critical care at Crozer-Chester Medical Center in Upland, Pa. The author has disclosed no potential conflicts of interest, financial or otherwise. BT - JAAPA : official journal of the American Academy of Physician Assistants C5 - Opioids & Substance Use CP - 11 CY - United States DO - 10.1097/01.JAA.0000525919.14882.ed IS - 11 JF - JAAPA : official journal of the American Academy of Physician Assistants LA - eng M1 - Journal Article N2 - Combination buprenorphine-naloxone is a cornerstone of outpatient treatment for substance use disorder, and is more widely accessible in primary care. Because oral buprenorphine has been diverted and abused for its euphoric properties, a combination formulation was developed and will trigger withdrawal symptoms if injected IV. PP - United States PY - 2017 SN - 1547-1896; 0893-7400 SP - 44 EP - 45 EP - T1 - Why is buprenorphine coformulated with naloxone? T2 - JAAPA : official journal of the American Academy of Physician Assistants TI - Why is buprenorphine coformulated with naloxone? U1 - Opioids & Substance Use U2 - 29064938 U3 - 10.1097/01.JAA.0000525919.14882.ed VL - 30 VO - 1547-1896; 0893-7400 Y1 - 2017 Y2 - Nov ER -