TY - JOUR
KW - Analgesics, Opioid/adverse effects
KW - Female
KW - Humans
KW - Infant, Newborn
KW - Length of Stay/economics/statistics & numerical data
KW - Male
KW - Methadone/administration & dosage
KW - Neonatal Abstinence Syndrome/drug therapy
KW - Opiate Substitution Treatment/methods
KW - Pregnancy
KW - Prenatal Exposure Delayed Effects/drug therapy
KW - Retrospective Studies
KW - South Carolina
KW - Urine/chemistry
AU - Jennifer Hudson
AU - Rachel Mayo
AU - Lori Dickes
AU - Liwei Chen
AU - Windsor Westbrook Sherrill
AU - Julie Summey
AU - Bradley Dalton
AU - Kindal Dankovich
A1 - 
AB - Objective To describe medical, safety, and health care utilization outcomes associated with an early treatment model for neonatal opioid withdrawal. Study Design This is a retrospective review of 117 opioid-exposed infants born in a large regional hospital and treated in the level I nursery with methadone initiated within 48 hours of birth. Results For this cohort, mean length of stay was 8.3 days. Hospital safety events were infrequent; there were no medication errors or deaths. Within 30 days of discharge, 14% of infants visited the emergency department; 7% were readmitted. Per birth, mean hospital charges were $10,946.96; mean costs were $5,908.93. Conclusion This study is the first to describe an early treatment model in a low-acuity nursery to prevent severe neonatal opioid withdrawal. The described model may be safe, effective, low-cost, and feasible for replication.
AD - Department of Pediatrics, Greenville Health System, Greenville, South Carolina.; Department of Public Health Sciences, Clemson University, Clemson, South Carolina.; Department of Parks, Recreation, and Tourism Management, Clemson University, Clemson, South Carolina.; Department of Public Health Sciences, Clemson University, Clemson, South Carolina.; Department of Public Health Sciences, Clemson University, Clemson, South Carolina.; Department of Public Health Sciences, Clemson University, Clemson, South Carolina.; Department of Public Health Sciences, Clemson University, Clemson, South Carolina.; University of South Carolina School of Medicine Greenville, Greenville, South Carolina.
BT - American Journal of Perinatology
C5 - Financing & Sustainability; Healthcare Disparities; Opioids & Substance Use
CP - 6
CY - United States
DO - 10.1055/s-0036-1596054
IS - 6
JF - American Journal of Perinatology
LA - eng
M1 - Journal Article
N2 - Objective To describe medical, safety, and health care utilization outcomes associated with an early treatment model for neonatal opioid withdrawal. Study Design This is a retrospective review of 117 opioid-exposed infants born in a large regional hospital and treated in the level I nursery with methadone initiated within 48 hours of birth. Results For this cohort, mean length of stay was 8.3 days. Hospital safety events were infrequent; there were no medication errors or deaths. Within 30 days of discharge, 14% of infants visited the emergency department; 7% were readmitted. Per birth, mean hospital charges were $10,946.96; mean costs were $5,908.93. Conclusion This study is the first to describe an early treatment model in a low-acuity nursery to prevent severe neonatal opioid withdrawal. The described model may be safe, effective, low-cost, and feasible for replication.
PB - USA
PP - United States
PY - 2017
SN - 1098-8785; 0735-1631
SP - 576
EP - 584
EP - 
T1 - Early Treatment for Neonatal Abstinence Syndrome: A Palliative Approach
T2 - American Journal of Perinatology
TI - Early Treatment for Neonatal Abstinence Syndrome: A Palliative Approach
U1 - Financing & Sustainability; Healthcare Disparities; Opioids & Substance Use
U2 - 27907936
U3 - 10.1055/s-0036-1596054
VL - 34
VO - 1098-8785; 0735-1631
Y1 - 2017
Y2 - May
ER -