TY - JOUR KW - Baltimore/epidemiology KW - Cost-Benefit Analysis KW - Drug Overdose/mortality/prevention & control KW - HIV Infections/economics/prevention & control KW - Harm Reduction KW - Hepatitis C/economics/prevention & control KW - Heroin Dependence/complications/economics/therapy KW - Humans KW - Models, Organizational KW - Needle-Exchange Programs/economics/organization & administration KW - Opiate Substitution Treatment/economics KW - Public Health KW - Baltimore, Maryland KW - Cost-benefit KW - cost-effectiveness KW - Heroin KW - Opiate Overdose KW - People who inject drugs KW - Supervised consumption rooms KW - Supervised injection facility AU - Amos Irwin AU - Ehsan Jozaghi AU - Brian W. Weir AU - Sean T. Allen AU - Andrew Lindsay AU - Susan G. Sherman A1 - AB - BACKGROUND: In Baltimore, MD, as in many cities throughout the USA, overdose rates are on the rise due to both the increase of prescription opioid abuse and that of fentanyl and other synthetic opioids in the drug market. Supervised injection facilities (SIFs) are a widely implemented public health intervention throughout the world, with 97 existing in 11 countries worldwide. Research has documented the public health, social, and economic benefits of SIFs, yet none exist in the USA. The purpose of this study is to model the health and financial costs and benefits of a hypothetical SIF in Baltimore. METHODS: We estimate the benefits by utilizing local health data and data on the impact of existing SIFs in models for six outcomes: prevented human immunodeficiency virus transmission, Hepatitis C virus transmission, skin and soft-tissue infection, overdose mortality, and overdose-related medical care and increased medication-assisted treatment for opioid dependence. RESULTS: We predict that for an annual cost of $1.8 million, a single SIF would generate $7.8 million in savings, preventing 3.7 HIV infections, 21 Hepatitis C infections, 374 days in the hospital for skin and soft-tissue infection, 5.9 overdose deaths, 108 overdose-related ambulance calls, 78 emergency room visits, and 27 hospitalizations, while bringing 121 additional people into treatment. CONCLUSIONS: We conclude that a SIF would be both extremely cost-effective and a significant public health and economic benefit to Baltimore City. AD - Law Enforcement Action Partnership, Silver Spring, MD, USA. Amos@LawEnforcementAction.org.; Criminal Justice Policy Foundation, Silver Spring, MD, USA. Amos@LawEnforcementAction.org.; British Columbia Centre for Disease Control, University of British Columbia, Vancouver, Canada.; School of Population and Public Health, University of British Columbia, Baltimore, MD, USA.; Department of Health, Behavior, and Society, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.; Department of Health, Behavior, and Society, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.; Department of Health, Behavior, and Society, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.; Criminal Justice Policy Foundation, Amherst College, Silver Spring, MD, USA. BT - Harm reduction journal C5 - Financing & Sustainability; Healthcare Disparities; Opioids & Substance Use CP - 1 CY - England DO - 10.1186/s12954-017-0153-2 IS - 1 JF - Harm reduction journal LA - eng M1 - Journal Article N2 - BACKGROUND: In Baltimore, MD, as in many cities throughout the USA, overdose rates are on the rise due to both the increase of prescription opioid abuse and that of fentanyl and other synthetic opioids in the drug market. Supervised injection facilities (SIFs) are a widely implemented public health intervention throughout the world, with 97 existing in 11 countries worldwide. Research has documented the public health, social, and economic benefits of SIFs, yet none exist in the USA. The purpose of this study is to model the health and financial costs and benefits of a hypothetical SIF in Baltimore. METHODS: We estimate the benefits by utilizing local health data and data on the impact of existing SIFs in models for six outcomes: prevented human immunodeficiency virus transmission, Hepatitis C virus transmission, skin and soft-tissue infection, overdose mortality, and overdose-related medical care and increased medication-assisted treatment for opioid dependence. RESULTS: We predict that for an annual cost of $1.8 million, a single SIF would generate $7.8 million in savings, preventing 3.7 HIV infections, 21 Hepatitis C infections, 374 days in the hospital for skin and soft-tissue infection, 5.9 overdose deaths, 108 overdose-related ambulance calls, 78 emergency room visits, and 27 hospitalizations, while bringing 121 additional people into treatment. CONCLUSIONS: We conclude that a SIF would be both extremely cost-effective and a significant public health and economic benefit to Baltimore City. PP - England PY - 2017 SN - 1477-7517; 1477-7517 SP - 29 T1 - Mitigating the heroin crisis in Baltimore, MD, USA: a cost-benefit analysis of a hypothetical supervised injection facility T2 - Harm reduction journal TI - Mitigating the heroin crisis in Baltimore, MD, USA: a cost-benefit analysis of a hypothetical supervised injection facility U1 - Financing & Sustainability; Healthcare Disparities; Opioids & Substance Use U2 - 28532488 U3 - 10.1186/s12954-017-0153-2 VL - 14 VO - 1477-7517; 1477-7517 Y1 - 2017 Y2 - May 12 ER -