TY - JOUR KW - Adolescent KW - Adult KW - Aged KW - Depression/psychology/therapy KW - Female KW - Follow-Up Studies KW - Humans KW - Male KW - Middle Aged KW - Obesity/psychology/therapy KW - Primary Health Care KW - Public Health AU - M. A. Lewis AU - L. K. Wagner AU - L. G. Rosas AU - N. Lv AU - E. M. Venditti AU - L. E. Steinman AU - B. J. Weiner AU - J. D. Goldhaber-Fiebert AU - M. B. Snowden AU - J. Ma A1 - AB - BACKGROUND: An integrated collaborative care intervention was used to treat primary care patients with comorbid obesity and depression in a randomized clinical trial. To increase wider uptake and dissemination, information is needed on translational potential. METHODS: The trial collected longitudinal, qualitative data at baseline, 6 months (end of intensive treatment), 12 months (end of maintenance treatment), and 24 months (end of follow-up). Semi-structured interviews (n = 142) were conducted with 54 out of 409 randomly selected trial participants and 37 other stakeholders, such as recruitment staff, intervention staff, and clinicians. Using a Framework Analysis approach, we examined themes across time and stakeholder groups according to the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework. RESULTS: At baseline, participants and other stakeholders reported being skeptical of the collaborative care approach related to some RE-AIM dimensions. However, over time they indicated greater confidence regarding the potential for future public health impact. They also provided information on barriers and actionable information to enhance program reach, effectiveness, adoption, implementation, and maintenance. CONCLUSIONS: RE-AIM provided a useful framework for understanding how to increase the impact of a collaborative and integrative approach for treating comorbid obesity and depression. It also demonstrates the utility of using the framework as a planning tool early in the evidence-generation pipeline. AD - Center for Communication Science, RTI International, Seattle, WA, United States of America.; Center for Communication Science, RTI International, Research Triangle Park, NC, United States of America.; Department of Epidemiology and Population Health, Stanford School of Medicine, Palo Alto, CA, United States of America.; Institute of Health Research and Policy, University of Illinois at Chicago, Chicago, IL, United States of America.; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America.; Health Promotion Research Center, University of Washington, Seattle, WA, United States of America.; Department of Global Health, University of Washington, Seattle, WA, United States of America.; Department of Health Services, University of Washington, Seattle, WA, United States of America.; Stanford Health Policy, Centers for Health Policy and Primary Care and Outcomes Research, Stanford University, Palo Alto, CA, United States of America.; Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle, WA, United States of America.; Institute of Health Research and Policy, University of Illinois at Chicago, Chicago, IL, United States of America.; Department of Medicine, College of Medicine, University of Illinois at Chicago, Chicago, IL, United States of America. BT - PloS one C5 - Healthcare Disparities CP - 3 DO - 10.1371/journal.pone.0248339 IS - 3 JF - PloS one LA - eng M1 - Journal Article N2 - BACKGROUND: An integrated collaborative care intervention was used to treat primary care patients with comorbid obesity and depression in a randomized clinical trial. To increase wider uptake and dissemination, information is needed on translational potential. METHODS: The trial collected longitudinal, qualitative data at baseline, 6 months (end of intensive treatment), 12 months (end of maintenance treatment), and 24 months (end of follow-up). Semi-structured interviews (n = 142) were conducted with 54 out of 409 randomly selected trial participants and 37 other stakeholders, such as recruitment staff, intervention staff, and clinicians. Using a Framework Analysis approach, we examined themes across time and stakeholder groups according to the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework. RESULTS: At baseline, participants and other stakeholders reported being skeptical of the collaborative care approach related to some RE-AIM dimensions. However, over time they indicated greater confidence regarding the potential for future public health impact. They also provided information on barriers and actionable information to enhance program reach, effectiveness, adoption, implementation, and maintenance. CONCLUSIONS: RE-AIM provided a useful framework for understanding how to increase the impact of a collaborative and integrative approach for treating comorbid obesity and depression. It also demonstrates the utility of using the framework as a planning tool early in the evidence-generation pipeline. PY - 2021 SN - 1932-6203; 1932-6203 T1 - Using RE-AIM to examine the potential public health impact of an integrated collaborative care intervention for weight and depression management in primary care: Results from the RAINBOW trial T2 - PloS one TI - Using RE-AIM to examine the potential public health impact of an integrated collaborative care intervention for weight and depression management in primary care: Results from the RAINBOW trial U1 - Healthcare Disparities U2 - 33705465 U3 - 10.1371/journal.pone.0248339 VL - 16 VO - 1932-6203; 1932-6203 Y1 - 2021 Y2 - Mar 11 ER -