TY - JOUR KW - Case-Control Studies KW - Delivery of Health Care, Integrated/organization & administration KW - Humans KW - Israel KW - Nigeria KW - United Kingdom KW - United States KW - Vietnam KW - EPIS framework KW - Global healthcare KW - integrated care KW - Multiple case study AU - N. A. Stadnick AU - E. Sadler AU - J. Sandall AU - C. F. Turienzo AU - I. M. Bennett AU - J. Borkan AU - B. Oladeji AU - O. Gureje AU - G. A. Aarons AU - M. Sklar A1 - AB - BACKGROUND: Integrated care is the coordination of general and behavioral health and is a highly promising and practical approach to improving healthcare delivery and patient outcomes. While there is growing interest and investment in integrated care implementation internationally, there are no formal guidelines for integrated care implementation applicable to diverse healthcare systems. Furthermore, there is a complex interplay of factors at multiple levels of influence that are necessary for successful implementation of integrated care in health systems. METHODS: Guided by the Exploration, Preparation, Implementation, Sustainment (EPIS) framework (Aarons et al., 2011), a multiple case study design was used to address two research objectives: 1) To highlight current integrated care implementation efforts through seven international case studies that target a range of healthcare systems, patient populations and implementation strategies and outcomes, and 2) To synthesize the shared and unique challenges and successes across studies using the EPIS framework. RESULTS: The seven reported case studies represent integrated care implementation efforts from five countries and continents (United States, United Kingdom, Vietnam, Israel, and Nigeria), target a range of clinical populations and care settings, and span all phases of the EPIS framework. Qualitative synthesis of these case studies illuminated common outer context, inner context, bridging and innovation factors that were key drivers of implementation. CONCLUSIONS: We propose an agenda that outlines priority goals and related strategies to advance integrated care implementation research. These goals relate to: 1) the role of funding at multiple levels of implementation, 2) meaningful collaboration with stakeholders across phases of implementation and 3) clear communication to stakeholders about integrated care implementation. TRIAL REGISTRATION: Not applicable. AD - Department of Psychiatry, University of California San Diego, La Jolla, USA. nstadnick@ucsd.edu.; Child and Adolescent Services Research Center, San Diego, USA. nstadnick@ucsd.edu.; Health Service & Population Research Department, Centre for Implementation Science, King's College London, London, UK.; Department of Nursing, Midwifery and Health, School of Health Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.; Department of Women and Children's Health, School of Life Course Sciences, Faculty of Life Sciences & Medicine, King's College London, London, UK.; Department of Women and Children's Health, School of Life Course Sciences, Faculty of Life Sciences & Medicine, King's College London, London, UK.; Department of Family Medicine, University of Washington, Seattle, USA.; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, USA.; Department of Global Health, University of Washington, Seattle, USA.; Department of Family Medicine, Brown University, Providence, USA.; Department of Psychiatry, College of Medicine, University of Ibadan, Ibadan, Nigeria.; Department of Psychiatry, College of Medicine, University of Ibadan, Ibadan, Nigeria.; Department of Psychiatry, University of California San Diego, La Jolla, USA.; Child and Adolescent Services Research Center, San Diego, USA.; Department of Psychiatry, University of California San Diego, La Jolla, USA.; Child and Adolescent Services Research Center, San Diego, USA. BT - BMC health services research C5 - Education & Workforce CP - 1 CY - England DO - 10.1186/s12913-019-4661-5 IS - 1 JF - BMC health services research LA - eng M1 - Journal Article N2 - BACKGROUND: Integrated care is the coordination of general and behavioral health and is a highly promising and practical approach to improving healthcare delivery and patient outcomes. While there is growing interest and investment in integrated care implementation internationally, there are no formal guidelines for integrated care implementation applicable to diverse healthcare systems. Furthermore, there is a complex interplay of factors at multiple levels of influence that are necessary for successful implementation of integrated care in health systems. METHODS: Guided by the Exploration, Preparation, Implementation, Sustainment (EPIS) framework (Aarons et al., 2011), a multiple case study design was used to address two research objectives: 1) To highlight current integrated care implementation efforts through seven international case studies that target a range of healthcare systems, patient populations and implementation strategies and outcomes, and 2) To synthesize the shared and unique challenges and successes across studies using the EPIS framework. RESULTS: The seven reported case studies represent integrated care implementation efforts from five countries and continents (United States, United Kingdom, Vietnam, Israel, and Nigeria), target a range of clinical populations and care settings, and span all phases of the EPIS framework. Qualitative synthesis of these case studies illuminated common outer context, inner context, bridging and innovation factors that were key drivers of implementation. CONCLUSIONS: We propose an agenda that outlines priority goals and related strategies to advance integrated care implementation research. These goals relate to: 1) the role of funding at multiple levels of implementation, 2) meaningful collaboration with stakeholders across phases of implementation and 3) clear communication to stakeholders about integrated care implementation. TRIAL REGISTRATION: Not applicable. PP - England PY - 2019 SN - 1472-6963; 1472-6963 SP - 899 T1 - Comparative case studies in integrated care implementation from across the globe: a quest for action T2 - BMC health services research TI - Comparative case studies in integrated care implementation from across the globe: a quest for action U1 - Education & Workforce U2 - 31775740 U3 - 10.1186/s12913-019-4661-5 VL - 19 VO - 1472-6963; 1472-6963 Y1 - 2019 Y2 - Nov 27 ER -