TY - JOUR
KW - Adult
KW - Anxiety/psychology
KW - Bayes Theorem
KW - Comorbidity
KW - Depression/psychology
KW - Factor Analysis, Statistical
KW - Female
KW - Humans
KW - Iran/epidemiology
KW - Male
KW - medically unexplained symptoms
KW - Mental Health
KW - Middle Aged
KW - Neuroticism
KW - Personality
KW - Prevalence
KW - Primary Health Care
KW - Psychophysiologic Disorders/epidemiology/psychology
KW - Regression Analysis
KW - Stress, Psychological/psychology
KW - Surveys and Questionnaires
KW - Bayesian regularized quantile regression
KW - Personality traits
KW - Somatic symptom
AU - S. Mostafaei
AU - K. Kabir
AU - A. Kazemnejad
AU - A. Feizi
AU - M. Mansourian
AU - Hassanzadeh Keshteli
AU - H. Afshar
AU - S. M. Arzaghi
AU - Rasekhi Dehkordi
AU - P. Adibi
AU - F. Ghadirian
A1 - 
AB - BACKGROUND: Somatic syndrome is one of the remarkably prevalent issues in primary health care and subspecialty settings. We aimed to elucidate multidimensional associations between somatic symptoms with major mental problems and personality traits in the framework of the quantile regression model with a Bayesian approach. METHODS: A total of 4763 employees at Isfahan University of Medical Sciences and Health Services in Isfahan province, Iran, filled out four validated questionnaires including Hospital Anxiety and Depression Scale (HADS), NEO Questionnaire, General Health Questionnaire (GHQ) and PHQ-15 for somatic symptom severity. In addition, Functional Gastrointestinal Disorders (FGIDs) were determined using Rome IV criteria. Exploratory Factor Analysis (EFA) and Bayesian regularized quantile regression with adaptive LASSO penalization were applied for reduced dimension of somatic symptoms and variable selection and parameter estimation, respectively. RESULTS: The 25 major somatic symptoms were grouped into four factors including general, upper gastrointestinal, lower gastrointestinal and respiratory by EFA. Stress, depression, and anxiety had significant effects on all of the four extracted factors. The effect of anxiety in each four extracted factors was more than stress and depression. Neuroticism and agreeableness had significant effects on all of the four extracted factors, generally (p < 0.05). CONCLUSIONS: Given the high prevalence of somatic symptoms and psychosomatic complaints in correlation with the diverse range of mental co-morbidities, developing more detailed diagnostic tools and methods is crucial; nonetheless, it seems that providing better interdisciplinary approaches in general medical practice is groundwork.
AD - Department of Community Medicine, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran. shayan.mostafaei@kums.ac.ir.; Epidemiology and Biostatistics Unit, Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran. shayan.mostafaei@kums.ac.ir.; Department of Community Medicine, Faculty of Medicine, Non-communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran.; Department of Biostatistics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.; Department of Epidemiology and Biostatistics, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran.; Department of Epidemiology and Biostatistics, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran.; Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.; Department of Medicine, University of Alberta, Edmonton, AB, Canada.; Psychosomatic Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.; Elderly Health Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.; Department of Biostatistics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.; Department of Medicine, University of Alberta, Edmonton, AB, Canada.; Department of Psychiatric Nursing, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran. f-ghadirianb@tums.ac.ir.; International Network of Integrated Nursing (INICN), Universal Scientific Education and Research (USERN), Tehran, Iran. f-ghadirianb@tums.ac.ir.
BT - BMC psychiatry
C5 - Education & Workforce; Healthcare Disparities; Measures; Medically Unexplained Symptoms
CP - 1
CY - England
DO - 10.1186/s12888-019-2189-1
IS - 1
JF - BMC psychiatry
LA - eng
M1 - Journal Article
N2 - BACKGROUND: Somatic syndrome is one of the remarkably prevalent issues in primary health care and subspecialty settings. We aimed to elucidate multidimensional associations between somatic symptoms with major mental problems and personality traits in the framework of the quantile regression model with a Bayesian approach. METHODS: A total of 4763 employees at Isfahan University of Medical Sciences and Health Services in Isfahan province, Iran, filled out four validated questionnaires including Hospital Anxiety and Depression Scale (HADS), NEO Questionnaire, General Health Questionnaire (GHQ) and PHQ-15 for somatic symptom severity. In addition, Functional Gastrointestinal Disorders (FGIDs) were determined using Rome IV criteria. Exploratory Factor Analysis (EFA) and Bayesian regularized quantile regression with adaptive LASSO penalization were applied for reduced dimension of somatic symptoms and variable selection and parameter estimation, respectively. RESULTS: The 25 major somatic symptoms were grouped into four factors including general, upper gastrointestinal, lower gastrointestinal and respiratory by EFA. Stress, depression, and anxiety had significant effects on all of the four extracted factors. The effect of anxiety in each four extracted factors was more than stress and depression. Neuroticism and agreeableness had significant effects on all of the four extracted factors, generally (p < 0.05). CONCLUSIONS: Given the high prevalence of somatic symptoms and psychosomatic complaints in correlation with the diverse range of mental co-morbidities, developing more detailed diagnostic tools and methods is crucial; nonetheless, it seems that providing better interdisciplinary approaches in general medical practice is groundwork.
PP - England
PY - 2019
SN - 1471-244X; 1471-244X
SP - 207
T1 - Explanation of somatic symptoms by mental health and personality traits: application of Bayesian regularized quantile regression in a large population study
T2 - BMC psychiatry
TI - Explanation of somatic symptoms by mental health and personality traits: application of Bayesian regularized quantile regression in a large population study
U1 - Education & Workforce; Healthcare Disparities; Measures; Medically Unexplained Symptoms
U2 - 31269925
U3 - 10.1186/s12888-019-2189-1
VL - 19
VO - 1471-244X; 1471-244X
Y1 - 2019
Y2 - Jul 3
ER -