TY - JOUR KW - drug efficacy KW - cost-effectiveness KW - adjunctive personalized psychosocial intervention treatment-resistant maintenance KW - opioid agonist therapy KW - Pragmatics KW - Randomized Controlled Trials KW - Clinical Trial KW - Empirical Study KW - Interview KW - Quantitative Study KW - Human KW - Male KW - Female KW - Adulthood (18 yrs & older) KW - Intervention KW - Costs and Cost Analysis KW - Drug Therapy KW - Opiates KW - Psychosocial Rehabilitation KW - Adjunctive Treatment KW - Treatment Resistant Disorders KW - cocaine KW - Maintenance Therapy KW - Treatment Effectiveness Evaluation KW - Precision Medicine KW - United Kingdom KW - article KW - 3383:Drug & Alcohol Rehabilitation KW - Quality-Adjusted Life Years KW - Analgesics, Opioid KW - Humans KW - Middle Aged KW - Treatment Outcome KW - Combined Modality Therapy KW - cognitive behavioral therapy KW - Cost-Benefit Analysis KW - Intention to Treat Analysis KW - opioid-related disorders KW - Adult KW - Opiate Substitution Treatment AU - John Marsden AU - Garry Stillwell AU - Kirsty James AU - James Shearer AU - Sarah Byford AU - Jennifer Hellier AU - Michael Kelleher AU - Joanna Kelly AU - Caroline Murphy AU - Luke Mitcheson A1 - AD - Addictions Department, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom john.marsden@kcl.ac.uk; Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom ; King’s Health Economics, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom ; Lambeth Addictions, South London and Maudsley NHS Mental Health Foundation Trust, London, United Kingdom ; King’s Clinical Trials Unit at King’s Health Partne, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom ; King's Clinical Trials Unit at King's Health Partners, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom ; Marsden, John,DeCrespigny Park, Denmark Hill,London,United Kingdom,SE5 8AF,Addictions Department, Institute of Psychiatry, Psychology and Neuroscience, King’s College London,john.marsden@kcl.ac.uk BT - The Lancet Psychiatry C5 - Education & Workforce; Financing & Sustainability; Opioids & Substance Use CP - 5 DO - 10.1016/S2215-0366(19)30097-5 IS - 5 JF - The Lancet Psychiatry LA - English M1 - Journal Article PB - Elsevier Science David Collingdre PY - 2019 SN - 2215-0366, 2215-0366 SP - 391 EP - 402 EP - T1 - Efficacy and cost-effectiveness of an adjunctive personalised psychosocial intervention in treatment-resistant maintenance opioid agonist therapy: A pragmatic, open-label, randomised controlled trial T2 - The Lancet Psychiatry TI - Efficacy and cost-effectiveness of an adjunctive personalised psychosocial intervention in treatment-resistant maintenance opioid agonist therapy: A pragmatic, open-label, randomised controlled trial U1 - Education & Workforce; Financing & Sustainability; Opioids & Substance Use U3 - 10.1016/S2215-0366(19)30097-5 UR - https://www.proquest.com/scholarly-journals/efficacy-cost-effectiveness-adjunctive/docview/2229358968/se-2?accountid=28100 VL - 6 VO - 2215-0366, 2215-0366 Y1 - 2019 Y2 - 05 ER -