TY - JOUR
KW - Adult
KW - Analgesics, Opioid
KW - Buprenorphine/analysis/urine
KW - Drug Evaluation, Preclinical/methods/statistics & numerical data
KW - Female
KW - Humans
KW - Opioid-Related Disorders/diagnosis/epidemiology
KW - Pregnancy
KW - Prenatal Care/methods/statistics & numerical data
KW - Prevalence
KW - Tennessee
AU - C. Alexander
AU - K. Breuel
AU - M. Olsen
A1 - 
AB - OBJECTIVES: To define the magnitude of buprenorphine presence in the urine drug screens of pregnant women and to assess the presence of illicit buprenorphine use versus the presence of prescribed buprenorphine use. METHODS: Initial prenatal drug screen results for all pregnant patients in our practice for a 1-year period were analyzed and tabulated. RESULTS: Buprenorphine was found in the urine drug screens of 16% of pregnant patients. The presence of buprenorphine was by far the highest for any substance associated with neonatal abstinence syndrome (NAS). We estimate that the exposure to buprenorphine of approximately one-third of individuals in our population is associated with illicit buprenorphine use. CONCLUSIONS: The high rate of NAS in our region is primarily associated with both illicit and prescribed buprenorphine rather than other substances. Buprenorphine usage at the time that prenatal care is initiated, rather than opiate use at the onset of prenatal care, is the underlying factor that must be addressed if our region is to successfully combat our high rates of NAS.
AD - From the Department of Obstetrics and Gynecology, Quillen College of Medicine, East Tennessee State University, Johnson City.; From the Department of Obstetrics and Gynecology, Quillen College of Medicine, East Tennessee State University, Johnson City.; From the Department of Obstetrics and Gynecology, Quillen College of Medicine, East Tennessee State University, Johnson City.
BT - Southern medical journal
C5 - Healthcare Disparities; Opioids & Substance Use
CP - 3
CY - United States
DO - 10.14423/SMJ.0000000000001072
IS - 3
JF - Southern medical journal
LA - eng
M1 - Journal Article
N2 - OBJECTIVES: To define the magnitude of buprenorphine presence in the urine drug screens of pregnant women and to assess the presence of illicit buprenorphine use versus the presence of prescribed buprenorphine use. METHODS: Initial prenatal drug screen results for all pregnant patients in our practice for a 1-year period were analyzed and tabulated. RESULTS: Buprenorphine was found in the urine drug screens of 16% of pregnant patients. The presence of buprenorphine was by far the highest for any substance associated with neonatal abstinence syndrome (NAS). We estimate that the exposure to buprenorphine of approximately one-third of individuals in our population is associated with illicit buprenorphine use. CONCLUSIONS: The high rate of NAS in our region is primarily associated with both illicit and prescribed buprenorphine rather than other substances. Buprenorphine usage at the time that prenatal care is initiated, rather than opiate use at the onset of prenatal care, is the underlying factor that must be addressed if our region is to successfully combat our high rates of NAS.
PP - United States
PY - 2020
SN - 1541-8243; 0038-4348
SP - 111
EP - 115
EP - 
T1 - High Prevalence of Buprenorphine in Prenatal Drug Screens in an Appalachian City
T2 - Southern medical journal
TI - High Prevalence of Buprenorphine in Prenatal Drug Screens in an Appalachian City
U1 - Healthcare Disparities; Opioids & Substance Use
U2 - 32123924
U3 - 10.14423/SMJ.0000000000001072
VL - 113
VO - 1541-8243; 0038-4348
Y1 - 2020
Y2 - Mar
ER -