TY - JOUR KW - Diagnosis, Differential KW - Diagnostic and Statistical Manual of Mental Disorders KW - Humans KW - Mental Disorders/classification/diagnosis KW - Patient Care/methods KW - Primary Health Care/methods KW - Somatoform Disorders/classification/diagnosis AU - R. C. Smith AU - F. C. Dwamena A1 - AB - Patients with medically unexplained symptoms (MUS) have little or no demonstrable disease explanation for the symptoms, and comorbid psychiatric disorders are frequent. Although common, costly, distressed, and often receiving ill-advised testing and treatments, most MUS patients go unrecognized, which precludes effective treatment. To enhance recognition, we present an emerging perspective that envisions a unitary classification for the entire spectrum of MUS where this diagnosis comprises severity, duration, and comorbidity. We then present a specific approach for making the diagnosis at each level of severity. Although our disease-based diagnosis system dictates excluding organic disease to diagnose MUS, much exclusion can occur clinically without recourse to laboratory or consultative evaluation because the majority of patients are mild. Only the less common, "difficult" patients with moderate and severe MUS require investigation to exclude organic diseases. By explicitly diagnosing and labeling all severity levels of MUS, we propose that this diagnostic approach cannot only facilitate effective treatment but also reduce the cost and morbidity from unnecessary interventions. BT - Journal of general internal medicine C5 - Medically Unexplained Symptoms CP - 5 CY - United States DO - 10.1007/s11606-006-0067-2 IS - 5 JF - Journal of general internal medicine N2 - Patients with medically unexplained symptoms (MUS) have little or no demonstrable disease explanation for the symptoms, and comorbid psychiatric disorders are frequent. Although common, costly, distressed, and often receiving ill-advised testing and treatments, most MUS patients go unrecognized, which precludes effective treatment. To enhance recognition, we present an emerging perspective that envisions a unitary classification for the entire spectrum of MUS where this diagnosis comprises severity, duration, and comorbidity. We then present a specific approach for making the diagnosis at each level of severity. Although our disease-based diagnosis system dictates excluding organic disease to diagnose MUS, much exclusion can occur clinically without recourse to laboratory or consultative evaluation because the majority of patients are mild. Only the less common, "difficult" patients with moderate and severe MUS require investigation to exclude organic diseases. By explicitly diagnosing and labeling all severity levels of MUS, we propose that this diagnostic approach cannot only facilitate effective treatment but also reduce the cost and morbidity from unnecessary interventions. PP - United States PY - 2007 SN - 1525-1497; 0884-8734 SP - 685 EP - 691 EP - T1 - Classification and diagnosis of patients with medically unexplained symptoms T2 - Journal of general internal medicine TI - Classification and diagnosis of patients with medically unexplained symptoms U1 - Medically Unexplained Symptoms U2 - 17443380 U3 - 10.1007/s11606-006-0067-2 VL - 22 VO - 1525-1497; 0884-8734 Y1 - 2007 ER -