TY - JOUR
KW - Buprenorphine/adverse effects/therapeutic use/urine
KW - Drug Interactions
KW - Humans
KW - Illicit Drugs/adverse effects/urine
KW - Opiate Substitution Treatment/methods
KW - Opioid-Related Disorders/drug therapy/urine
KW - Substance Abuse Detection/methods
KW - Urine drug testing
KW - buprenorphine
KW - definitive urine drug testing
KW - medication treatment
KW - Office-based opioid treatment
KW - opioid use disorder
KW - polysubstance use
KW - presumptive urine drug testing
KW - substance use disorders
AU - A. G. Barthwell
AU - J. Allgaier
AU - K. Egli
A1 - 
AB - Individuals who receive buprenorphine treatment for opioid use disorder in office-based settings may be at risk for, or have a history of, polysubstance use. Urine drug testing is an important clinical tool for monitoring medication adherence and patient stability; and screening for illicit drug use and dangerous drug-drug interactions. This article is intended to educate practitioners in office-based opioid treatment settings on selecting appropriate substances for a definitive drug testing panel that are known to be used concurrently, sequentially, or in combination with buprenorphine for opioid use disorder. It is also intended to educate such practitioners on selecting appropriate testing technology to reduce risks to the health and safety of patients prescribed buprenorphine for opioid use disorder. In developing this article, the author conducted a search from May 2018 through December 2017 of peer-reviewed and government-supported articles in electronic databases. The literature showed that several common substances are often abused in conjunction with certain other substances, increasing the risk of serious adverse events, including death. Whether used on their own, concurrently, sequentially, or in combination, substances of abuse carry significant health risks. Definitive urine drug testing, given its high specificity and sensitivity, can accurately identify the use of specific prescription medications and illicit substances that, especially when taken with buprenorphine or other substances, may cause harm to a patient. When testing for buprenorphine and other opioids; sedatives, hypnotics, and anxiolytics; cocaine; amphetamines; and PCP and other club drugs, providers in office-based opioid treatment settings are strongly advised to use definitive urine drug tests as the primary testing methodology. In addition, practitioners must be able to identify all other substances that a patient may be consuming, taking into consideration the patient's historical and current drugs of choice, given that concurrent use with buprenorphine or other substances may cause serious adverse events. This article highlights the pressing market demand for comprehensive, definitive urine drug testing at a more reasonable cost.
AD - a Encounter Medical Group , Oak Park , IL , USA.; b PLLC , Ideal Option , Kennewick , WA , USA.; b PLLC , Ideal Option , Kennewick , WA , USA.
BT - Critical reviews in toxicology
C5 - Opioids & Substance Use
CP - 10
CY - England
DO - 10.1080/10408444.2018.1553935
IS - 10
JF - Critical reviews in toxicology
LA - eng
M1 - Journal Article
N2 - Individuals who receive buprenorphine treatment for opioid use disorder in office-based settings may be at risk for, or have a history of, polysubstance use. Urine drug testing is an important clinical tool for monitoring medication adherence and patient stability; and screening for illicit drug use and dangerous drug-drug interactions. This article is intended to educate practitioners in office-based opioid treatment settings on selecting appropriate substances for a definitive drug testing panel that are known to be used concurrently, sequentially, or in combination with buprenorphine for opioid use disorder. It is also intended to educate such practitioners on selecting appropriate testing technology to reduce risks to the health and safety of patients prescribed buprenorphine for opioid use disorder. In developing this article, the author conducted a search from May 2018 through December 2017 of peer-reviewed and government-supported articles in electronic databases. The literature showed that several common substances are often abused in conjunction with certain other substances, increasing the risk of serious adverse events, including death. Whether used on their own, concurrently, sequentially, or in combination, substances of abuse carry significant health risks. Definitive urine drug testing, given its high specificity and sensitivity, can accurately identify the use of specific prescription medications and illicit substances that, especially when taken with buprenorphine or other substances, may cause harm to a patient. When testing for buprenorphine and other opioids; sedatives, hypnotics, and anxiolytics; cocaine; amphetamines; and PCP and other club drugs, providers in office-based opioid treatment settings are strongly advised to use definitive urine drug tests as the primary testing methodology. In addition, practitioners must be able to identify all other substances that a patient may be consuming, taking into consideration the patient's historical and current drugs of choice, given that concurrent use with buprenorphine or other substances may cause serious adverse events. This article highlights the pressing market demand for comprehensive, definitive urine drug testing at a more reasonable cost.
PP - England
PY - 2018
SN - 1547-6898; 1040-8444
SP - 829
EP - 852
EP - 
T1 - Definitive urine drug testing in office-based opioid treatment: a literature review
T2 - Critical reviews in toxicology
TI - Definitive urine drug testing in office-based opioid treatment: a literature review
U1 - Opioids & Substance Use
U2 - 30794024
U3 - 10.1080/10408444.2018.1553935
VL - 48
VO - 1547-6898; 1040-8444
Y1 - 2018
Y2 - Nov
ER -